Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments.
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The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathwayLabeling of fusion proteins with synthetic fluorophores in live cellsCharacterization of the intracellular deproteinized relaxed circular DNA of hepatitis B virus: an intermediate of covalently closed circular DNA formationTranscriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptationMolecular heterogeneity in glioblastoma: potential clinical implicationsMolecular cloning and functional analysis of a human cDNA encoding an Escherichia coli AlkB homolog, a protein involved in DNA alkylation damage repairNuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agentsInduction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen speciesMolecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatusRemoval of O6-methylguanine from plant DNA in vivo is accelerated under conditions of clastogenic adaptation.Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors.Aspirin inhibits the SHH/GLI1 signaling pathway and sensitizes malignant glioma cells to temozolomide therapy.Comprehensive analysis of MGMT promoter methylation: correlation with MGMT expression and clinical response in GBMO6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction.PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.Diet-induced obesity modulates epigenetic responses to ionizing radiation in mice.Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations.Strategic down-regulation of DNA polymerase beta by antisense RNA sensitizes mammalian cells to specific DNA damaging agents.Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in LungSelf-destruction and tolerance in resistance of mammalian cells to alkylation damage.Combined analysis of O6-methylguanine-DNA methyltransferase protein expression and promoter methylation provides optimized prognostication of glioblastoma outcome.MGMT: a personal perspective.rhoB encoding a UV-inducible Ras-related small GTP-binding protein is regulated by GTPases of the Rho family and independent of JNK, ERK, and p38 MAP kinase.Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes.Targeting O⁶-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy.Progression of O⁶-methylguanine-DNA methyltransferase and temozolomide resistance in cancer research.Temozolomide in combination with carbon ion or photon irradiation in glioblastoma multiforme cell lines - does scheduling matter?Influence of DNA repair on nonlinear dose-responses for mutation.Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage.MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma.Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts.Contribution of O6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: new insights gained from studies of genetically engineered mammalian cell lines.The ras-related small GTP-binding protein RhoB is immediate-early inducible by DNA damaging treatments.p53-Mediated down-regulation of the human DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) via interaction with Sp1 transcription factor.MGMT as a potential stratification marker in relapsed high-grade glioma of children: the HIT-GBM experience.MGMT promoter methylation in non-neoplastic brain.Prognostic impact of O6-methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation: a prospective patient cohort.MGMT in primary and recurrent human glioblastomas after radiation and chemotherapy and comparison with p53 status and clinical outcome.Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of MGMT and BCL-XL.The proline rich domain of p53 is dispensable for MGMT-dependent DNA repair and cell survival following alkylation damage.
P2860
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P2860
Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Inducibility of the DNA repair ...... ls by DNA-damaging treatments.
@ast
Inducibility of the DNA repair ...... ls by DNA-damaging treatments.
@en
type
label
Inducibility of the DNA repair ...... ls by DNA-damaging treatments.
@ast
Inducibility of the DNA repair ...... ls by DNA-damaging treatments.
@en
prefLabel
Inducibility of the DNA repair ...... ls by DNA-damaging treatments.
@ast
Inducibility of the DNA repair ...... ls by DNA-damaging treatments.
@en
P2093
P2860
P356
P1476
Inducibility of the DNA repair ...... ls by DNA-damaging treatments.
@en
P2093
P2860
P304
P356
10.1128/MCB.11.9.4660
P407
P577
1991-09-01T00:00:00Z