Transcriptional regulation and expression of CYP3A4 in hepatocytes.
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Genetic predictors of interindividual variability in hepatic CYP3A4 expressionThree-dimensional Huh7 cell culture system for the study of Hepatitis C virus infectionEnhancement of CYP3A4 activity in Hep G2 cells by lentiviral transfection of hepatocyte nuclear factor-1 alphaGenome-wide discovery of drug-dependent human liver regulatory elementsRifampicin Does not Significantly Affect the Expression of Small Heterodimer Partner in Primary Human HepatocytesThe influence of standardized Valeriana officinalis extract on the CYP3A1 gene expression by nuclear receptors in in vivo model.No correlation of hsa-miR-148a with expression of PXR or CYP3A4 in human livers from Chinese Han population.Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism.Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 geneIntrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in men.The role of CYP3A4 mRNA transcript with shortened 3'-untranslated region in hepatocyte differentiation, liver development, and response to drug induction.Hypolipidemic agent Z-guggulsterone: metabolism interplays with induction of carboxylesterase and bile salt export pumpThe Epoxyeicosatrienoic Acid Pathway Enhances Hepatic Insulin Signaling and is Repressed in Insulin-Resistant Mouse Liver.Molecular and macromolecular alterations of recombinant adenoviral vectors do not resolve changes in hepatic drug metabolism during infectionMolecular mechanisms underlying chemical liver injury.Inflammation and CYP3A4-mediated drug metabolism in advanced cancer: impact and implications for chemotherapeutic drug dosing.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy.Long-term virus-induced alterations of CYP3A-mediated drug metabolism: a look at the virology, immunology and molecular biology of a multi-faceted problem.The effect of microRNAs in the regulation of human CYP3A4: a systematic study using a mathematical modelThe missing linkage: what pharmacogenetic associations are left to find in CYP3A?Mechanisms of ketamine-involved regulation of cytochrome P450 gene expression.Ambient tonicity and intestinal cytochrome CYP3A.Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids.The effect and clinical consequences of hypoxia on cytochrome P450, membrane carrier proteins activity and expression.Toxicological implications of modulation of gene expression by microRNAs.Post-translational and post-transcriptional modifications of pregnane X receptor (PXR) in regulation of the cytochrome P450 superfamily.Cytochrome P450 enzyme regulation by glucocorticoids and consequences in terms of drug interaction.Interethnic differences in pharmacokinetics of antibacterials.Phenotypic regulation of liver cells in a biofunctionalized three-dimensional hydrogel platform.Hsa-miR-27a is involved in the regulation of CYP3A4 expression in human livers from Chinese Han population.Modulation of CYP3A4 activity and induction of apoptosis, necrosis and senescence by the anti-tumour imidazoacridinone C-1311 in human hepatoma cells.Towards personalized medicine with a three-dimensional micro-scale perfusion-based two-chamber tissue model systemMicroarray Analysis of Differentially-Expressed Genes Encoding CYP450 and Phase II Drug Metabolizing Enzymes in Psoriasis and Melanoma.Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study.Systematical analysis of impacts of heat stress on the proliferation, apoptosis and metabolism of mouse hepatocyte.U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells.Effect of triacontanol on the pharmacokinetics of docetaxel in rats associated with induction of cytochrome P450 3A1/2.Study of the upregulation of the activity of cytochrome P450 3A isoforms by Astragalus injection and Astragalus granules in rats and in cells.
P2860
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P2860
Transcriptional regulation and expression of CYP3A4 in hepatocytes.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Transcriptional regulation and expression of CYP3A4 in hepatocytes.
@ast
Transcriptional regulation and expression of CYP3A4 in hepatocytes.
@en
type
label
Transcriptional regulation and expression of CYP3A4 in hepatocytes.
@ast
Transcriptional regulation and expression of CYP3A4 in hepatocytes.
@en
prefLabel
Transcriptional regulation and expression of CYP3A4 in hepatocytes.
@ast
Transcriptional regulation and expression of CYP3A4 in hepatocytes.
@en
P50
P1476
Transcriptional regulation and expression of CYP3A4 in hepatocytes
@en
P2093
M José Gómez-Lechón
P304
P356
10.2174/138920007779815986
P407
P577
2007-02-01T00:00:00Z