Laforin confers cancer resistance to energy deprivation-induced apoptosis.
about
Laforin is required for the functional activation of malin in endoplasmic reticulum stress resistance in neuronal cellsIncreased endoplasmic reticulum stress and decreased proteasomal function in lafora disease models lacking the phosphatase laforinLaforin, a dual specificity phosphatase involved in Lafora disease, is present mainly as monomeric form with full phosphatase activityLaforin prevents stress-induced polyglucosan body formation and Lafora disease progression in neurons.Deletions and missense mutations of EPM2A exacerbate unfolded protein response and apoptosis of neuronal cells induced by endoplasm reticulum stressActivating transcription factor 2 and c-Jun-mediated induction of FoxP3 for experimental therapy of mammary tumor in the mouse.Silencing of elongation factor-2 kinase potentiates the effect of 2-deoxy-D-glucose against human glioma cells through blunting of autophagy.
P2860
Q24320315-5AEC6680-1450-4B8E-8566-2A31572E1544Q33468448-3CE961F7-5309-422A-B26A-DA21F3F7B333Q34009801-EB3A6AAB-8B6C-43BB-BAC8-D6F625CD7A6BQ37043068-003FEA49-4AB2-480B-8E72-E0FB3C4CF308Q37239891-B3296845-679F-4F53-BDF3-443161718BAEQ37344195-A43F3A7B-B2D7-47DC-910C-3479DEED00D3Q39879662-D4097F23-0480-47B8-9036-5455210881E3
P2860
Laforin confers cancer resistance to energy deprivation-induced apoptosis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Laforin confers cancer resistance to energy deprivation-induced apoptosis.
@ast
Laforin confers cancer resistance to energy deprivation-induced apoptosis.
@en
type
label
Laforin confers cancer resistance to energy deprivation-induced apoptosis.
@ast
Laforin confers cancer resistance to energy deprivation-induced apoptosis.
@en
prefLabel
Laforin confers cancer resistance to energy deprivation-induced apoptosis.
@ast
Laforin confers cancer resistance to energy deprivation-induced apoptosis.
@en
P2093
P2860
P1433
P1476
Laforin confers cancer resistance to energy deprivation-induced apoptosis.
@en
P2093
P2860
P304
P356
10.1158/0008-5472.CAN-07-6314
P407
P577
2008-06-01T00:00:00Z