Human cytomegalovirus late protein encoded by ie2: a trans-activator as well as a repressor of gene expression.
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Transcriptional regulation of the human cytomegalovirus US11 early gene.Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant.Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.RelB-p50 NF-kappa B complexes are selectively induced by cytomegalovirus immediate-early protein 1: differential regulation of Bcl-x(L) promoter activity by NF-kappa B family membersEffective inhibition of human cytomegalovirus gene expression and replication by a ribozyme derived from the catalytic RNA subunit of RNase P from Escherichia coli.The IE2 60-kilodalton and 40-kilodalton proteins are dispensable for human cytomegalovirus replication but are required for efficient delayed early and late gene expression and production of infectious virus.Human cytomegalovirus UL102 geneMultiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infectionA cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2.The human cytomegalovirus 86-kilodalton major immediate-early protein interacts physically and functionally with histone acetyltransferase P/CAF.Viable human cytomegalovirus recombinant virus with an internal deletion of the IE2 86 gene affects late stages of viral replicationHuman cytomegalovirus IE72 protein interacts with the transcriptional repressor hDaxx to regulate LUNA gene expression during lytic infection.Human cytomegalovirus IE2 86 and IE2 40 proteins differentially regulate UL84 protein expression posttranscriptionally in the absence of other viral gene products.Development of cell lines that provide tightly controlled temporal translation of the human cytomegalovirus IE2 proteins for complementation and functional analyses of growth-impaired and nonviable IE2 mutant viruses.Contribution of GADD45 family members to cell death suppression by cellular Bcl-xL and cytomegalovirus vMIA.Translational regulation of the human cytomegalovirus pp28 (UL99) late geneIdentification of domains within the human cytomegalovirus major immediate-early 86-kilodalton protein and the retinoblastoma protein required for physical and functional interaction with each other.Internal deletions of IE2 86 and loss of the late IE2 60 and IE2 40 proteins encoded by human cytomegalovirus affect the levels of UL84 protein but not the amount of UL84 mRNA or the loading and distribution of the mRNA on polysomesHuman cytomegalovirus DNA replication requires transcriptional activation via an IE2- and UL84-responsive bidirectional promoter element within oriLyt.Small internal deletions in the human cytomegalovirus IE2 gene result in nonviable recombinant viruses with differential defects in viral gene expression.The carboxyl-terminal region of human cytomegalovirus IE1491aa contains an acidic domain that plays a regulatory role and a chromatin-tethering domain that is dispensable during viral replication.Induction of the RelB NF-kappaB subunit by the cytomegalovirus IE1 protein is mediated via Jun kinase and c-Jun/Fra-2 AP-1 complexes.The human cytomegalovirus UL112-113 locus can activate the full Kaposi's sarcoma-associated herpesvirus lytic replication cycle
P2860
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P2860
Human cytomegalovirus late protein encoded by ie2: a trans-activator as well as a repressor of gene expression.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Human cytomegalovirus late pro ...... repressor of gene expression.
@ast
Human cytomegalovirus late pro ...... repressor of gene expression.
@en
type
label
Human cytomegalovirus late pro ...... repressor of gene expression.
@ast
Human cytomegalovirus late pro ...... repressor of gene expression.
@en
prefLabel
Human cytomegalovirus late pro ...... repressor of gene expression.
@ast
Human cytomegalovirus late pro ...... repressor of gene expression.
@en
P2093
P1476
Human cytomegalovirus late pro ...... repressor of gene expression.
@en
P2093
Jenkins DE
Martens CL
Mocarski ES
P304
P356
10.1099/0022-1317-75-9-2337
P407
P478
75 ( Pt 9)
P577
1994-09-01T00:00:00Z