Individual Cas phosphorylation sites are dispensable for processive phosphorylation by Src and anchorage-independent cell growth
about
Phosphorylation mechanism and structure of serine-arginine protein kinasesSilencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell deathJNK Signaling: Regulation and Functions Based on Complex Protein-Protein PartnershipsAssociation of the breast cancer antiestrogen resistance protein 1 (BCAR1) and BCAR3 scaffolding proteins in cell signaling and antiestrogen resistanceA pre-metazoan origin of the CRK gene family and co-opted signaling networkLack of Csk-mediated negative regulation in a unicellular SRC kinase.The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein CasReengineering the signaling properties of a Src family kinase.The evolutionarily conserved arrangement of domains in SRC family kinases is important for substrate recognition.Signaling properties of a non-metazoan Src kinase and the evolutionary history of Src negative regulationCooperative activation of Src family kinases by SH3 and SH2 ligands.Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.Synthesis of functional signaling domains by combinatorial polymerization of phosphorylation motifs.SRC induces podoplanin expression to promote cell migrationIn vitro membrane reconstitution of the T-cell receptor proximal signaling network.Myristoylation and membrane binding regulate c-Src stability and kinase activityPKA and CDK5 can phosphorylate specific serines on the intracellular domain of podoplanin (PDPN) to inhibit cell motilityProcessive phosphorylation: mechanism and biological importanceEzrin Is Associated with Disease Progression in Ovarian Carcinoma.SRC points the way to biomarkers and chemotherapeutic targets.Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14AND-34/BCAR3 regulates adhesion-dependent p130Cas serine phosphorylation and breast cancer cell growth pattern.The ubiquitin-proteasome system regulates focal adhesions at the leading edge of migrating cells.The miR-24-3p/p130Cas: a novel axis regulating the migration and invasion of cancer cells.Cas utilizes Nck2 to activate Cdc42 and regulate cell polarization during cell migration in response to wound healing.Mechanism of dephosphorylation of the SR protein ASF/SF2 by protein phosphatase 1.Crk and CrkL adaptor proteins: networks for physiological and pathological signalingCoordinate suppression of Sdpr and Fhl1 expression in tumors of the breast, kidney, and prostate.Versatile regulation of multisite protein phosphorylation by the order of phosphate processing and protein-protein interactions.SRC utilizes Cas to block gap junctional communication mediated by connexin43.
P2860
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P2860
Individual Cas phosphorylation sites are dispensable for processive phosphorylation by Src and anchorage-independent cell growth
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Individual Cas phosphorylation ...... horage-independent cell growth
@ast
Individual Cas phosphorylation ...... horage-independent cell growth
@en
type
label
Individual Cas phosphorylation ...... horage-independent cell growth
@ast
Individual Cas phosphorylation ...... horage-independent cell growth
@en
prefLabel
Individual Cas phosphorylation ...... horage-independent cell growth
@ast
Individual Cas phosphorylation ...... horage-independent cell growth
@en
P2093
P2860
P356
P1476
Individual Cas phosphorylation ...... horage-independent cell growth
@en
P2093
Gary S Goldberg
Parag Patwardhan
W Todd Miller
Yongquan Shen
P2860
P304
20689-20697
P356
10.1074/JBC.M602311200
P407
P577
2006-05-17T00:00:00Z