Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis
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Breakdown of Epithelial Barrier Integrity and Overdrive Activation of Alveolar Epithelial Cells in the Pathogenesis of Acute Respiratory Distress Syndrome and Lung FibrosisMatrix biology of idiopathic pulmonary fibrosis: a workshop report of the national heart, lung, and blood instituteMechanisms of alveolar epithelial injury, repair, and fibrosisPulmonary fibrosis: patterns and perpetratorsModulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosisTargeting the isoprenoid pathway to abrogate progression of pulmonary fibrosisGenetically manipulated mouse models of lung disease: potential and pitfallsRegulation of myofibroblast differentiation by poly(ADP-ribose) polymerase 1Allosteric modulation of beta1 integrin function induces lung tissue repairFibrotic myofibroblasts manifest genome-wide derangements of translational controlLigand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition.Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary fibrosis.Tetraspanin CD151 protects against pulmonary fibrosis by maintaining epithelial integritybeta1-Integrin-collagen interaction suppresses FoxO3a by the coordination of Akt and PP2APathologic caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis.Pathogenesis of idiopathic pulmonary fibrosisDiminished prostaglandin E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosismiR-210 promotes IPF fibroblast proliferation in response to hypoxia.Lipopolysaccharide induces lung fibroblast proliferation through Toll-like receptor 4 signaling and the phosphoinositide3-kinase-Akt pathwayMicroRNA-96 inhibits FoxO3a function in IPF fibroblasts on type I collagen matrix.Roles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice.Reactive response of fibrocytes to vocal fold mucosal injury in ratSignaling pathways in the epithelial origins of pulmonary fibrosisFoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas.PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis.Integrating mechanisms of pulmonary fibrosisIPF fibroblasts are desensitized to type I collagen matrix-induced cell death by suppressing low autophagy via aberrant Akt/mTOR kinasesPlasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungsPathological alteration of FoxO3a activity promotes idiopathic pulmonary fibrosis fibroblast proliferation on type i collagen matrixIntegrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of AktReemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis.The Akt inhibitor, triciribine, ameliorates chronic hypoxia-induced vascular pruning and TGFβ-induced pulmonary fibrosis.Pathologic Regulation of Collagen I by an Aberrant Protein Phosphatase 2A/Histone Deacetylase C4/MicroRNA-29 Signal Axis in Idiopathic Pulmonary Fibrosis FibroblastsReduced FoxO3a expression causes low autophagy in idiopathic pulmonary fibrosis fibroblasts on collagen matrices.Low α(2)β(1) integrin function enhances the proliferation of fibroblasts from patients with idiopathic pulmonary fibrosis by activation of the β-catenin pathway.Down-regulation of USP13 mediates phenotype transformation of fibroblasts in idiopathic pulmonary fibrosisEvaluation of PTEN immunoexpression in oral submucous fibrosis: role in pathogenesis and malignant transformationmiR-31 is a negative regulator of fibrogenesis and pulmonary fibrosis.Molecular and cellular mechanisms of pulmonary fibrosis.Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction.
P2860
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P2860
Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Pathological integrin signalin ...... idiopathic pulmonary fibrosis
@ast
Pathological integrin signalin ...... idiopathic pulmonary fibrosis
@en
type
label
Pathological integrin signalin ...... idiopathic pulmonary fibrosis
@ast
Pathological integrin signalin ...... idiopathic pulmonary fibrosis
@en
prefLabel
Pathological integrin signalin ...... idiopathic pulmonary fibrosis
@ast
Pathological integrin signalin ...... idiopathic pulmonary fibrosis
@en
P2093
P2860
P356
P1476
Pathological integrin signalin ...... idiopathic pulmonary fibrosis
@en
P2093
Craig Henke
Deanna Diebold
Jill Kleidon
John Nerva
Mark Peterson
Richard Nho
Svetlana Avdulov
P2860
P304
P356
10.1084/JEM.20080001
P407
P577
2008-06-09T00:00:00Z