Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth.
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Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growthComputational modeling of interactions between multiple myeloma and the bone microenvironmentCanonical Wnt pathway inhibitor ICG-001 induces cytotoxicity of multiple myeloma cells in Wnt-independent mannerOsteoblastogenesis and tumor growth in myeloma.Advances in the understanding of myeloma bone disease and tumour growth.Fibroblast activation protein protects bortezomib-induced apoptosis in multiple myeloma cells through β-catenin signaling pathwayMultiple myeloma mesenchymal stromal cells: Contribution to myeloma bone disease and therapeuticsCYR61/CCN1 overexpression in the myeloma microenvironment is associated with superior survival and reduced bone diseasePredicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesisConsequences of daily administered parathyroid hormone on myeloma growth, bone disease, and molecular profiling of whole myelomatous bone.Wnt3a expression is associated with epithelial-mesenchymal transition and promotes colon cancer progressionβ-catenin SUMOylation is involved in the dysregulated proliferation of myeloma cellsCharacterization of the molecular mechanism of the bone-anabolic activity of carfilzomib in multiple myeloma.Human placenta-derived adherent cells prevent bone loss, stimulate bone formation, and suppress growth of multiple myeloma in bonePharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft modelRole of decorin in the antimyeloma effects of osteoblasts.Characterization of Wnt/beta-catenin signalling in osteoclasts in multiple myeloma.Genetic polymorphisms of EPHX1, Gsk3beta, TNFSF8 and myeloma cell DKK-1 expression linked to bone disease in myelomaThe proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivo.The role of Dickkopf-1 in bone development, homeostasis, and diseaseWNT/beta-catenin signaling is involved in regulation of osteoclast differentiation by human immunodeficiency virus protease inhibitor ritonavir: relationship to human immunodeficiency virus-linked bone mineral lossBortezomib induces osteoblast differentiation via Wnt-independent activation of beta-catenin/TCF signaling.Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma.The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growth.Cancer phenotype as the outcome of an evolutionary game between normal and malignant cellsDickkopf-1: a suitable target for the management of myeloma bone disease.Tumor-host cell interactions in the bone disease of myeloma.Proteasome inhibitors and bone disease.Preclinical models of multiple myeloma: a critical appraisal.The ecology of cancer from an evolutionary game theory perspective.The osteoblastic niche in the context of multiple myeloma.The WNT system: background and its role in bone.Wnt/β-catenin signaling in bone marrow niche.MAF protein mediates innate resistance to proteasome inhibition therapy in multiple myeloma.Relationship between abnormal osteoblasts and cellular immunity in multiple myeloma.Transcriptomic profile induced in bone marrow mesenchymal stromal cells after interaction with multiple myeloma cells: implications in myeloma progression and myeloma bone disease.Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin.Pathogenesis of bone disease in multiple myeloma: from bench to bedside.Myeloma cells inhibit non-canonical wnt co-receptor ror2 expression in human bone marrow osteoprogenitor cells: effect of wnt5a/ror2 pathway activation on the osteogenic differentiation impairment induced by myeloma cells.Wnt signaling in multiple myeloma: a central player in disease with therapeutic potential.
P2860
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P2860
Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth.
@ast
Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth.
@en
type
label
Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth.
@ast
Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth.
@en
prefLabel
Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth.
@ast
Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth.
@en
P2860
P1433
P1476
Wnt3a signaling within bone inhibits multiple myeloma bone disease and tumor growth.
@en
P2093
John D Shaughnessy
Ya-Wei Qiang
P2860
P304
P356
10.1182/BLOOD-2007-10-120253
P407
P577
2008-03-14T00:00:00Z