A specific enzyme-linked immunosorbent assay for measuring beta-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease
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Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brainLeptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's diseaseDays to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomersAlzheimer's disease and insulin resistance: translating basic science into clinical applicationsPlatelets and Alzheimer's disease: Potential of APP as a biomarkerA window into the heterogeneity of human cerebrospinal fluid Aβ peptidesSynaptopathies: synaptic dysfunction in neurological disorders - A review from students to studentsBeta-amyloid deposition in chronic traumatic encephalopathyFerulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic miceAmyloid beta from axons and dendrites reduces local spine number and plasticity.The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy.Evaluating amyloid-β oligomers in cerebrospinal fluid as a biomarker for Alzheimer's diseaseBrain interstitial oligomeric amyloid β increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease.Evaluation of neural damage in Duchenne muscular dystrophy patients.Saliva levels of Abeta1-42 as potential biomarker of Alzheimer's disease: a pilot study.A vaccine with Aβ oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer's diseaseThe Alzheimer's disease mitochondrial cascade hypothesisNeuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease.The future of blood-based biomarkers for Alzheimer's disease.Soluble amyloid beta levels are elevated in the white matter of Alzheimer's patients, independent of cortical plaque severity.Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice.d-serine levels in Alzheimer's disease: implications for novel biomarker developmentBiomarkers of the dementia.Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.Characterization of oligomer formation of amyloid-beta peptide using a split-luciferase complementation assayELISA measurement of specific non-antigen-bound antibodies to Aβ1-42 monomer and soluble oligomers in sera from Alzheimer's disease, mild cognitively impaired, and noncognitively impaired subjectsSOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer diseaseSoluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's diseaseSignal loss due to oligomerization in ELISA analysis of amyloid-beta can be recovered by a novel sample pre-treatment method.Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice.The aqueous phase of Alzheimer's disease brain contains assemblies built from ∼4 and ∼7 kDa Aβ species.Reliable Measurements of the β-Amyloid Pool in Blood Could Help in the Early Diagnosis of AD.APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease.Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls.New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF.Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis.Monoclonal antibody with conformational specificity for a toxic conformer of amyloid β42 and its application toward the Alzheimer's disease diagnosis.Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer's disease.Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains.Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate.
P2860
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P2860
A specific enzyme-linked immunosorbent assay for measuring beta-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
A specific enzyme-linked immun ...... atients with Alzheimer disease
@en
type
label
A specific enzyme-linked immun ...... atients with Alzheimer disease
@en
prefLabel
A specific enzyme-linked immun ...... atients with Alzheimer disease
@en
P2093
P2860
P1433
P1476
A specific enzyme-linked immun ...... atients with Alzheimer disease
@en
P2093
Dennis J Selkoe
Dominic M Walsh
Ganesh Shankar
Imelda M Smith
Weiming Xia
P2860
P304
P356
10.1001/ARCHNEUROL.2008.565
P577
2009-02-01T00:00:00Z