about
A large repertoire of parasite epitopes matched by a large repertoire of host immune receptors in an invertebrate host/parasite modelAPOBEC3 proteins mediate the clearance of foreign DNA from human cellsOptimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brainGenetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivoThe RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substratesOncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switchingEndonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regionsHoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutationMicroRNA-155 suppresses activation-induced cytidine deaminase-mediated Myc-Igh translocationDNA mismatch repair: molecular mechanism, cancer, and ageingEssential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytesThe germinal center antibody response in health and diseaseMutations, kataegis and translocations in B cells: understanding AID promiscuous activityCan Peto's paradox be used as the null hypothesis to identify the role of evolution in natural resistance to cancer? A critical reviewAntibody Affinity Maturation in Fishes-Our Current UnderstandingKinetic models reveal the in vivo mechanisms of mutagenesis in microbes and manMolecular programming of B cell memoryThe APOBEC3 family of retroelement restriction factorsTranscriptional stalling in B-lymphocytes: a mechanism for antibody diversification and maintenance of genomic integrityDNA triplet repeat expansion and mismatch repairRelated Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationMSH2/MSH6 complex promotes error-free repair of AID-induced dU:G mispairs as well as error-prone hypermutation of A:T sitesActivation-induced deoxycytidine deaminase (AID) co-transcriptional scanning at single-molecule resolution.Hepatitis C Virus (HCV)-Induced Immunoglobulin Hypermutation Reduces the Affinity and Neutralizing Activities of Antibodies against HCV Envelope ProteinMechanism of somatic hypermutation at the WA motif by human DNA polymerase η.Reshaping Antibody DiversityAID targeting is dependent on RNA polymerase II pausing.Spt2p defines a new transcription-dependent gross chromosomal rearrangement pathway.DNA Damage: From Chronic Inflammation to Age-Related DeteriorationSnaps and mends: DNA breaks and chromosomal translocationsAID/APOBEC deaminases and cancerMolecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancerConvergent transcription at intragenic super-enhancers targets AID-initiated genomic instabilityAID targeting: old mysteries and new challengesBase excision repairSimultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesionsMutation of POLB causes lupus in miceSimultaneous in vitro characterisation of DNA deaminase function and associated DNA repair pathwaysProcessive DNA demethylation via DNA deaminase-induced lesion resolution
P2860
Q21562261-3A8F2316-7DB4-46B5-B4C1-97CB24EE802AQ24294583-9D5DE178-0C84-4B66-89FC-36C1B6BC2ED6Q24297481-4C183734-4260-4ED7-9145-5180DA5388DBQ24299862-ADE9D3B3-73A2-48A2-A851-26377F7D29AEQ24305160-35C66D33-AC63-4A31-9C8C-9E2186956D5AQ24337929-4DAC86ED-5DB6-4AB4-BA86-5A007786E135Q24569801-6C2E5316-96CC-4376-893B-6E33FCB8566BQ24623341-B0F28234-4AD0-4D63-AA54-01C99F9557FEQ24645030-9B3409D4-422F-46F0-A443-63C5D7A058CFQ24646923-9919466A-AF00-4058-93F3-DEC5697FD2E5Q24647002-84CFF8F1-D64F-46B1-839F-78559960B8B7Q24649590-6878F1C9-25C1-433C-B9E5-3CD1394B11E5Q26745929-1BC09347-B7C7-48E8-BC85-43EF8505BAA1Q26768663-6E11C84A-7756-4AB5-B2FD-9A38C99E5979Q26779417-0E5F3C2F-9598-4D41-9DFC-A5C214F8FEC3Q26799165-4EA49CC2-AA1F-499E-8060-C95C03535520Q26829150-2C93FA96-4CB9-4664-8261-5AD95140682AQ26829944-C36F5790-338B-47F2-AB9A-8F49AB2EC156Q26862780-3C802822-0ADD-453D-866B-51B662DF4C00Q26862917-18839C65-C6D3-4FC9-B338-A31E7821140DQ26996542-F7412764-5D61-4ADB-BC15-26366F3F2C62Q27000758-34D266DB-46DD-417F-AE90-0E237BF7914DQ27324793-3272121D-5046-4D2A-BB58-05E86CFED789Q27337984-CC19045F-BFE4-4F70-84E4-9F5174987700Q27486411-720E85B4-B4EE-4604-9984-8925F05E335DQ27677864-5CB3B1A4-D4BD-4EE0-8495-4B1925F134F7Q27678538-F42C12F5-F06A-45B1-A2ED-C877B9014E58Q27692655-F056429D-16AC-482F-B21D-9966E507D2F0Q27938023-778D168A-13B6-474E-BCB0-A869709E3959Q28078628-939B1495-F8D7-496A-A40D-9FC5456B5F3AQ28082525-67279EA8-48D5-4B91-9C36-21B983DFCD6DQ28085553-45B4189E-DB24-48EA-9260-A584B9E459C8Q28088790-3128649D-C7C1-4BD2-B917-9560F4F8E4D9Q28253489-8CC22A77-8EED-47AA-ADC5-271287ED2EFAQ28265992-6842EDC5-BD5E-4C07-9277-56E699C8E4B4Q28288115-B032C205-A0CE-41EF-8313-50931D2077A9Q28475702-85C34AB7-9CC3-4E79-9C6D-8CF2A104A174Q28513579-DA2B430C-33C2-458F-82A7-D51097C07EFFQ28536559-BFBDBC1E-E4E0-4F5F-89C3-674373E95463Q28540726-50636B38-BC7A-464D-98B5-3BCBE9485BA1
P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Molecular mechanisms of antibody somatic hypermutation.
@en
type
label
Molecular mechanisms of antibody somatic hypermutation.
@en
prefLabel
Molecular mechanisms of antibody somatic hypermutation.
@en
P1476
Molecular mechanisms of antibody somatic hypermutation
@en
P2093
Michael S Neuberger
P356
10.1146/ANNUREV.BIOCHEM.76.061705.090740
P577
2007-01-01T00:00:00Z