Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts.
about
The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteinsHuman telomerase and its regulationControl of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1A biomarker that identifies senescent human cells in culture and in aging skin in vivoHuman cyclin E, a nuclear protein essential for the G1-to-S phase transitionRoles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapiesRegulation of the Telomerase Reverse Transcriptase Subunit through Epigenetic MechanismsInactivation of p53 and life span extension of human diploid fibroblasts by mot-2Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activityTelomere length predicts replicative capacity of human fibroblastsCritically short telomeres in acute myeloid leukemia with loss or gain of parts of chromosomes.Chromosome telomere integrity of human solid neoplasms.A reassessment of the telomere hypothesis of senescence.Role of telomerase in cellular proliferation and cancer.Human telomeres maintain their overhang length at senescence.Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence.Telomerase. A target for anticancer therapy.The role of senescence and immortalization in carcinogenesis.Barley telomeres shorten during differentiation but grow in callus culture.The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence.Induction of duplication reversion in human fibroblasts, by wild-type and mutated SV40 T antigen, covaries with the ability to induce host DNA synthesis.Culture, immortalization, and characterization of human meibomian gland epithelial cells.Role of SV40 integration site at chromosomal interval 1q21.1 in immortalized CRL2504 cells.Establishment of Hertwig's epithelial root sheath/epithelial rests of Malassez cell line from human periodontium.HuR uses AUF1 as a cofactor to promote p16INK4 mRNA decay.Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function.Homologous recombination in human telomerase-positive and ALT cells occurs with the same frequency.Differential gene expression in SV40-mediated immortalization of human fibroblasts.Senescence: does it all happen at the ends?Role of telomeres and telomerase in cancerCoordinated interactions of multiple POT1-TPP1 proteins with telomere DNA.Activation of telomerase in a human tumorSenescence of immortal human fibroblasts by the introduction of normal human chromosome 6Inhibition of prostate cancer cell colony formation by the flavonoid quercetin correlates with modulation of specific regulatory genes.Molecular changes with in vitro cellular senescence.Gene expression in quiescent and senescent fibroblasts.Characterization of human vascular smooth muscle cells transformed by the early genetic region of SV40 virus.Successful immortalization of endometrial glandular cells with normal structural and functional characteristics.Adenovirus type 12 early region 1B 54K protein significantly extends the life span of normal mammalian cells in culture
P2860
Q24313641-8F85166E-3749-4DA4-8AA7-8676601B1ADFQ24533247-05005C24-E343-4338-BB66-119B95288C32Q24540711-32AB4759-2E77-4441-89B8-4A59703AFB62Q24562644-B56671B7-C65E-4E91-982E-4AD2B7EBF03FQ24652527-9E6A6746-92DE-4EA6-A5A7-E5D86175A7A8Q26744271-8DDA3958-5DF5-446C-8375-4BE06FA493B3Q26744572-69403318-2B89-4E06-B023-2A6AE38B41BCQ28145704-CBDCE228-7693-4FFD-8219-49A2C3418FB9Q29615388-F11C0B00-FF99-4568-BBEE-5DCD1A80915BQ29615745-AC007B7F-3E79-40DF-B26C-36E84A4FF8DFQ33226956-A29FA2B0-81FD-4DEC-A3C2-93870410EB9CQ33278724-1D9DDDB8-12B5-468E-820C-4F274891AD5DQ33536846-3805B819-23C9-4007-85B7-FD24E258DA02Q33653970-BC43BD27-0EF7-44F5-8C77-1A329B14DDDFQ33707650-014C063E-AA91-4BEB-8173-7838A6760799Q33719354-462AD7C4-6FDD-4EAA-8EB7-70C67E74C003Q33833328-A801FD02-639C-4849-B6AC-A9DF6C515664Q33846221-01B4FB8A-972A-4FDE-9B4D-53D7BBDE8AF8Q33853382-1A45574B-F8C2-4B1B-BD8F-2852CC248ED5Q33889383-657076F0-5F7E-40FC-A8A7-097726A3A227Q33969339-38471684-DB30-4BDF-8C8D-FE87C37BF8E4Q33970521-1D087330-775D-4F2C-A4AA-691C917D25EDQ34022565-A61FA178-A2B8-4E62-887D-6B47BB47B2C4Q34035772-4D9B4034-AB80-4839-9834-E22726C5B1F8Q34043029-50BB0270-77C7-4353-8B1E-968956C3B8C2Q34045640-B67973FA-5704-4634-B4CF-8DD34758FD5DQ34194696-C8C9A197-24B6-420C-97B6-43862AF81F1BQ34250567-AF1FAAB3-D669-4FA8-B6F3-6504FC5E571CQ34428570-2E5103EE-165F-4010-AAED-A6DA96D9C97EQ34535679-9A3D75E4-A4A1-4CBC-A266-E9961FC8CB51Q34633162-DD89E349-76C5-47D7-BFC4-DCCAF4FF0BFCQ34686602-C4B6F49E-35A4-4148-BC22-803BA951E029Q35141128-E2A48719-6315-4637-85F6-E1F312A6EB17Q35472884-ACFEF31C-036E-4216-B89D-574C3DA12BEFQ35541796-1CBB18FD-DA3D-4E33-954A-69FFB5E6F6C6Q35656594-878BFE11-F739-4386-AC19-A29DF32AED2AQ35656600-BE15BCBE-CEBA-4BCA-97AE-0527E97A50C2Q35830821-6A47617F-5E6A-4C1A-A36D-AB19619FC654Q35843291-79901194-9B42-4F1C-B548-6022B811465EQ35891411-62185BAC-A0B7-4A33-8007-7D85DC10860A
P2860
Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Reversible cellular senescence ...... mal human diploid fibroblasts.
@ast
Reversible cellular senescence ...... mal human diploid fibroblasts.
@en
type
label
Reversible cellular senescence ...... mal human diploid fibroblasts.
@ast
Reversible cellular senescence ...... mal human diploid fibroblasts.
@en
prefLabel
Reversible cellular senescence ...... mal human diploid fibroblasts.
@ast
Reversible cellular senescence ...... mal human diploid fibroblasts.
@en
P2093
P2860
P356
P1476
Reversible cellular senescence ...... mal human diploid fibroblasts.
@en
P2093
O M Pereira-Smith
W E Wright
P2860
P304
P356
10.1128/MCB.9.7.3088
P407
P577
1989-07-01T00:00:00Z