Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function. - Wikidata - awgldk - TriplyDB

Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function.

Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function.

http://www.wikidata.org/entity/Q34194696

about

IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress Adenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction.Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis Acute activation of AMP-activated protein kinase prevents H2O2-induced premature senescence in primary human keratinocytes Activation of AMP-activated protein kinase by 3,3'-Diindolylmethane (DIM) is associated with human prostate cancer cell death in vitro and in vivo The LKB1-AMPK pathway: metabolism and growth control in tumour suppression Development of a human mitochondrial oligonucleotide microarray (h-MitoArray) and gene expression analysis of fibroblast cell lines from 13 patients with isolated F1Fo ATP synthase deficiency.Radiation induces senescence and a bystander effect through metabolic alterations PP2A mediated AMPK inhibition promotes HSP70 expression in heat shock response Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart Hypoxia, RONS and energy metabolism in articular cartilage.Cytosolic malate dehydrogenase regulates senescence in human fibroblasts.Enhanced proliferation of cultured human vascular smooth muscle cells linked to increased function of RNA-binding protein HuR LKB1 preserves genome integrity by stimulating BRCA1 expression.Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging 3'UTR elements inhibit Ras-induced C/EBPβ post-translational activation and senescence in tumour cells Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer Age-related changes in AMP-activated protein kinase after stroke Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells.Combined activation of the energy and cellular-defense pathways may explain the potent anti-senescence activity of methylene blue.Growth inhibition by miR-519 via multiple p21-inducing pathways.Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis Absence of AMPKα2 accelerates cellular senescence via p16 induction in mouse embryonic fibroblasts.Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.Temozolomide induces senescence but not apoptosis in human melanoma cells.Proteasome inhibitor PS-341 (VELCADE) induces stabilization of the TRAIL receptor DR5 mRNA through the 3'-untranslated region.From Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence.Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence.Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS.Diphosphoinositol polyphosphates: metabolic messengers?Piperine regulates UCP1 through the AMPK pathway by generating intracellular lactate production in muscle cells.The Role of Adenosine Signaling in Headache: A Review.SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model.Mitochondria in vascular disease.Reprofiling a classical anthelmintic, pyrvinium pamoate, as an anti-cancer drug targeting mitochondrial respiration.Cellular polarity in aging: role of redox regulation and nutrition.Role of AMP-activated protein kinase in cancer therapy.RNA-binding proteins as molecular links between cancer and neurodegeneration.

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P2860

Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function.

http://www.wikidata.org/entity/Q34194696

description

2003 nî lūn-bûn

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2003 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2003 թվականի մայիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Increased AMP:ATP ratio and AM ...... inked to reduced HuR function.

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Increased AMP:ATP ratio and AM ...... inked to reduced HuR function.

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Increased AMP:ATP ratio and AM ...... inked to reduced HuR function.

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type

label

Increased AMP:ATP ratio and AM ...... inked to reduced HuR function.

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Increased AMP:ATP ratio and AM ...... inked to reduced HuR function.

@en

Increased AMP:ATP ratio and AM ...... inked to reduced HuR function.

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prefLabel

Increased AMP:ATP ratio and AM ...... inked to reduced HuR function.

@ast

Increased AMP:ATP ratio and AM ...... inked to reduced HuR function.

@en

Increased AMP:ATP ratio and AM ...... inked to reduced HuR function.

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Journal of Biological Chemistry

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Increased AMP:ATP ratio and AM ...... inked to reduced HuR function.

@en

P2093

Wengong Wang

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Xiaoling Yang

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P2860

Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

AMP-activated kinase regulates cytoplasmic HuR.

HuR regulates p21 mRNA stabilization by UV light

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1

AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location

AU-rich elements: characterization and importance in mRNA degradation

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27016-27023

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scholarly article

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10.1074/JBC.M300318200

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29

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278

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Isabel López de Silanes

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2003-05-01T00:00:00Z

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12730239

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