about
Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivityVRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damagePBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21Oncogenic Intra-p53 Family Member Interactions in Human CancersMutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.More targets, more pathways and more clues for mutant p53.Algorithms for network-based identification of differential regulators from transcriptome data: a systematic evaluationExploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models.Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cellsMutant p53 gain-of-function in cancer.Impedimetric detection of mutant p53 biomarker-driven metastatic breast cancers under hyposmotic pressurePro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy.Grp1-associated scaffold protein regulates skin homeostasis after ultraviolet irradiation.Homozygous mdm2 SNP309 cancer cells with compromised transcriptional elongation at p53 target genes are sensitive to induction of p53-independent cell death.Molecular mechanism of mutant p53 stabilization: the role of HSP70 and MDM2.Sarcomas in TP53 germline mutation carriers: a review of the IARC TP53 database.Preferential binding of hot spot mutant p53 proteins to supercoiled DNA in vitro and in cells.REACTIN: regulatory activity inference of transcription factors underlying human diseases with application to breast cancer.Bioinformatics analysis of the serine and glycine pathway in cancer cellsUpregulation of the mitochondrial transport protein, Tim50, by mutant p53 contributes to cell growth and chemoresistanceToca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis.Comparison of effects of p53 null and gain-of-function mutations on salivary tumors in MMTV-Hras transgenic mice.Transcription factors and molecular epigenetic marks underlying EpCAM overexpression in ovarian cancerA computational model incorporating neural stem cell dynamics reproduces glioma incidence across the lifespan in the human populationTopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.Clinical implications of miRNAs in the pathogenesis, diagnosis and therapy of pancreatic cancer.MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of functionNucleolar GTP-binding Protein-1 (NGP-1) Promotes G1 to S Phase Transition by Activating Cyclin-dependent Kinase Inhibitor p21 Cip1/Waf1.Mutant p53: one name, many proteins.The Expression and Correlation of iNOS and p53 in Oral Squamous Cell CarcinomaΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammationExpression and significance of CHIP in canine mammary gland tumors.Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase AxlMutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expressionBench to bedside and back again: molecular mechanisms of alpha-catenin function and roles in tumorigenesis.Induction of genetic instability by gain-of-function p53 cancer mutants.The dark side of a tumor suppressor: anti-apoptotic p53.Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.Predicting disease progression after nephrectomy for localized renal cell carcinoma: the utility of prognostic models and molecular biomarkers.Expression of TP53 mutation-associated microRNAs predicts clinical outcome in head and neck squamous cell carcinoma patients.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Mutant p53: an oncogenic transcription factor.
@ast
Mutant p53: an oncogenic transcription factor.
@en
type
label
Mutant p53: an oncogenic transcription factor.
@ast
Mutant p53: an oncogenic transcription factor.
@en
prefLabel
Mutant p53: an oncogenic transcription factor.
@ast
Mutant p53: an oncogenic transcription factor.
@en
P2093
P2860
P356
P1433
P1476
Mutant p53: an oncogenic transcription factor.
@en
P2093
Blandino G
Dell'Orso S
Di Agostino S
Fontemaggi G
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210296
P407
P577
2007-04-01T00:00:00Z
P5875
P6179
1017331576