A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys.
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Protective efficacy of centralized and polyvalent envelope immunogens in an attenuated equine lentivirus vaccineSang Froid in a time of trouble: is a vaccine against HIV possible?Consensus HIV-1 FSU-A integrase gene variants electroporated into mice induce polyfunctional antigen-specific CD4+ and CD8+ T cellsMapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the Step studyDemonstration of cross-protective vaccine immunity against an emerging pathogenic Ebolavirus SpeciesHIV-1 vaccine development after STEP.Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys.Mosaic HIV-1 vaccines expand the breadth and depth of cellular immune responses in rhesus monkeys.Update on animal models for HIV research.Cross-reactive potential of human T-lymphocyte responses in HIV-1 infectionThe antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate.Similar T-cell immune responses induced by group M consensus env immunogens with wild-type or minimum consensus variable regions.Broad and cross-clade CD4+ T-cell responses elicited by a DNA vaccine encoding highly conserved and promiscuous HIV-1 M-group consensus peptides.The immune response during acute HIV-1 infection: clues for vaccine development.Allosteric induction of the CD4-bound conformation of HIV-1 Gp120.Focus and breadth of cellular immune responses elicited by a heterologous insert prime-boost vaccine regimen in rhesus monkeys.Comparison of Immunogenicity in Rhesus Macaques of Transmitted-Founder, HIV-1 Group M Consensus, and Trivalent Mosaic Envelope Vaccines Formulated as a DNA Prime, NYVAC, and Envelope Protein BoostInclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge.High-throughput quantitative real-time polymerase chain reaction array for absolute and relative quantification of rhesus macaque types I, II, and III interferon and their subtypesA Synthetic Porcine Reproductive and Respiratory Syndrome Virus Strain Confers Unprecedented Levels of Heterologous Protection.Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages.Hepatitis C genotype 1 mosaic vaccines are immunogenic in mice and induce stronger T-cell responses than natural strains.Breadth of cellular and humoral immune responses elicited in rhesus monkeys by multi-valent mosaic and consensus immunogens.Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1Rhesus macaques vaccinated with consensus envelopes elicit partially protective immune responses against SHIV SF162p4 challenge.Current understanding of HIV-associated neurocognitive disorders pathogenesis.Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccinationMinor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response.T-cell vaccine strategies for human immunodeficiency virus, the virus with a thousand faces.X4 human immunodeficiency virus type 1 gp120 down-modulates expression and immunogenicity of codelivered antigens.HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis.DNA vaccines: a rational design against parasitic diseases.Lessons learned from HIV vaccine clinical efficacy trials.Glycosylation site-specific analysis of clade C HIV-1 envelope proteins.Detailed characterization of antibody responses against HIV-1 group M consensus gp120 in rabbits.Immunogenicity of NYVAC prime-protein boost HIV-1 envelope vaccination and SHIV challenge of nonhuman primates.
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P2860
A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A centralized gene-based HIV-1 ...... e responses in rhesus monkeys.
@en
type
label
A centralized gene-based HIV-1 ...... e responses in rhesus monkeys.
@en
prefLabel
A centralized gene-based HIV-1 ...... e responses in rhesus monkeys.
@en
P2093
P2860
P50
P356
P1476
A centralized gene-based HIV-1 ...... e responses in rhesus monkeys.
@en
P2093
Norman L Letvin
Sampa Santra
P2860
P304
10489-10494
P356
10.1073/PNAS.0803352105
P407
P577
2008-07-23T00:00:00Z