Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.
about
Analysis of TP53 mutation spectra reveals the fingerprint of the potent environmental carcinogen, aristolochic acidBalkan endemic nephropathy: an update on its aetiologyDNA adductomicsMechanisms of enzyme-catalyzed reduction of two carcinogenic nitro-aromatics, 3-nitrobenzanthrone and aristolochic acid I: Experimental and theoretical approachesOrganic compounds in water extracts of coal: links to Balkan endemic nephropathyAn Integrated View of Aristolochic Acid Nephropathy: Update of the LiteratureMolecular characterization of preneoplastic lesions provides insight on the development of renal tumors.TP53 mutations in human cancers: origins, consequences, and clinical useAntineoplastic agents. 573. isolation and structure of papilistatin from the papilionid butterfly Byasa polyeuctes termessaLimitations and plausibility of the Pliocene lignite hypothesis in explaining the etiology of Balkan endemic nephropathyBenzo[a]pyrene, aflatoxine B₁ and acetaldehyde mutational patterns in TP53 gene using a functional assay: relevance to human cancer aetiologyContribution of biotransformation enzymes to the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions, difficult answersAssociation of a bitter taste receptor mutation with Balkan Endemic Nephropathy (BEN).«Suspects» in etiology of endemic nephropathy: aristolochic acid versus mycotoxinsBalkan endemic nephropathy-current status and future perspectives.Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2.A reassessment of risk associated with dietary intake of ochratoxin A based on a lifetime exposure modelNew Approaches for Biomonitoring Exposure to the Human Carcinogen Aristolochic Acid.A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches.Prediction and Characterisation of the System Effects of Aristolochic Acid: A Novel Joint Network Analysis towards Therapeutic and Toxicological Mechanisms.Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism.Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1.Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivoChronic kidney disease and cancer: a troubling connectionp53 mutations as fingerprints for aristolochic acid: an environmental carcinogen in endemic (Balkan) nephropathy.Human formalin-fixed paraffin-embedded tissues: an untapped specimen for biomonitoring of carcinogen DNA adducts by mass spectrometry.Increased mortality risk for cancers of the kidney and other urinary organs among Chinese herbalistsbeta-Naphthoflavone protects mice from aristolochic acid-I-induced acute kidney injury in a CYP1A dependent mechanism.Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model.Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid.Establishment of immortalized mesenchymal stem cells derived from the submandibular glands of tdTomato transgenic mice.Adenine versus guanine DNA adducts of aristolochic acids: role of the carcinogen-purine linkage in the differential global genomic repair propensity.JNK-dependent AP-1 activation is required for aristolochic acid-induced TGF-β1 synthesis in human renal proximal epithelial cells.Metabolic activation of diesel exhaust carcinogens in primary and immortalized human TP53 knock-in (Hupki) mouse embryo fibroblasts.Y27632 attenuates the aristolochic acid-promoted invasion and migration of human urothelial cancer TSGH cells in vitro and inhibits the growth of xenografts in vivo.Reduced kidney levels of lysophosphatidic acids in rats after chronic administration of aristolochic acid: Its possible protective role in renal fibrosisImpact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone.The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats.Preventing aristolochic acid nephropathy.Proteomics investigation on aristolochic acid nephropathy: a case study on rat kidney tissues.
P2860
Q27021933-B653A353-DBC6-499F-8594-1F5E81BD7A85Q28079308-5A81A009-27A5-4BF6-B00F-BC4C29F2564AQ28384534-50B63DF6-3979-4406-B4DF-63DE6124FCB9Q28390347-DDDC7626-F231-4C28-8E91-482F55126D8EQ28660859-B8A0D834-7676-400F-851B-C4A131F96325Q30238670-B1613F6E-C1AF-4355-8201-422A62635FF4Q33498333-67FA452E-F3D1-4B11-951F-D1753152FC8BQ33685392-C702F9A3-005B-4364-961A-74BB583BC91BQ33710637-25CA14BB-BE82-437A-8F62-1C2C89BF3203Q34065208-278421EF-DAD9-43DD-9DA6-D68BBFAEEBECQ34154683-4E8BEA3A-7E25-4411-A38C-D13999C2445DQ34359592-DB888865-BC3F-4ADC-872F-87581858523CQ34439063-2E973681-1CBD-4A48-9687-3908D52142ADQ35155823-55FE5D93-E191-4FD3-A1FE-43919546C5B6Q35452465-3FDC2E8B-D93F-4BA2-A21C-6B4CBFB88462Q35685368-173CE03E-E2AD-4ED9-846C-D70E7892A398Q35847068-4403B923-EEBF-40DE-A37F-50FA19CAB8F0Q36041371-67CD299B-7DA8-4A89-AB92-3D0E9396623DQ36324758-F62495EC-8C97-4724-A6EC-411D6AF1E128Q36333565-E58C25F0-87A0-4007-8E7F-6A2B2293F1EBQ36564307-C35EDC6E-0470-48CE-8620-E4968E790784Q36667086-81FC83A3-A2E6-45F9-8860-DAFEA9A34730Q36721027-E08E0F54-8E2A-4C42-B530-925AC52BA7D6Q36773023-5CB267FF-A837-4F09-8946-E9B2B9C62D94Q37311820-5CF07727-9A7B-4056-BA26-D744B65E771FQ37523243-AC4CC22E-B78E-49D8-8B97-D34FFEEB2E25Q37583172-71BADC28-9D69-4030-A29F-0C9A3499404DQ37729300-6A7F30D1-975D-4373-A447-A656488FEFD0Q37765653-F94B9DDD-0B35-4E7E-A0DF-2D2582008AEAQ38154957-DF165E60-6D1C-4A34-ACE5-FD4EFD29D62FQ38815512-158610EB-9E95-4A38-B5A2-827EBA166C53Q38984760-C7286513-34A6-477D-A94B-86EDA8D6B293Q39375030-01E5DC81-6341-4C57-9696-81BEEF426A36Q39393226-59FA9988-B87C-471D-9B97-CD2BA96BE949Q39498880-DB16EC74-A79D-4648-AC54-C22CD3FC46F6Q41680429-9DE3628B-B4CB-481B-9BF1-C72CD3A76D09Q42157886-8F41027D-5107-4493-AF46-23F1AA201CD9Q42704240-E867CDB7-23F2-42D9-8923-E9F7DD7E001EQ43132918-10177F59-0883-41A9-8E82-2183BD237B76Q44217954-131E372E-4CE8-49CE-8718-6032A54B60E8
P2860
Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Aristolochic acid mutagenesis: ...... -associated urothelial cancer.
@ast
Aristolochic acid mutagenesis: ...... -associated urothelial cancer.
@en
type
label
Aristolochic acid mutagenesis: ...... -associated urothelial cancer.
@ast
Aristolochic acid mutagenesis: ...... -associated urothelial cancer.
@en
prefLabel
Aristolochic acid mutagenesis: ...... -associated urothelial cancer.
@ast
Aristolochic acid mutagenesis: ...... -associated urothelial cancer.
@en
P2093
P50
P356
P1433
P1476
Aristolochic acid mutagenesis: ...... y-associated urothelial cancer
@en
P2093
Heinz H Schmeiser
Jochen vom Brocke
Joelle L Nortier
Maria L Simões
Monica Hollstein
P304
P356
10.1093/CARCIN/BGM082
P407
P577
2007-04-13T00:00:00Z