The recent medicinal chemistry development of Jak2 tyrosine kinase small molecule inhibitors.
about
JAK2 Inhibition: Reviewing a New Therapeutical Option in Myeloproliferative NeoplasmsResearch and progress on ClC‑2 (Review).The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis.A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growthRedox regulation of Janus kinase: The elephant in the room.Upregulation of the large conductance voltage- and Ca2+-activated K+ channels by Janus kinase 2.Enhancing specificity in the Janus kinases: a study on the thienopyridine JAK2 selective mechanism combined molecular dynamics simulation.Downregulation of KCNQ4 by Janus kinase 2.Down-regulation of the epithelial Na⁺ channel ENaC by Janus kinase 2.Down-regulation of the myoinositol transporter SMIT by JAK2.Downregulation of the creatine transporter SLC6A8 by JAK2.
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P2860
The recent medicinal chemistry development of Jak2 tyrosine kinase small molecule inhibitors.
description
2010 nî lūn-bûn
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
@zh-hk
2010年論文
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2010年論文
@zh-tw
2010年论文
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2010年论文
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2010年论文
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name
The recent medicinal chemistry ...... ase small molecule inhibitors.
@ast
The recent medicinal chemistry ...... ase small molecule inhibitors.
@en
type
label
The recent medicinal chemistry ...... ase small molecule inhibitors.
@ast
The recent medicinal chemistry ...... ase small molecule inhibitors.
@en
prefLabel
The recent medicinal chemistry ...... ase small molecule inhibitors.
@ast
The recent medicinal chemistry ...... ase small molecule inhibitors.
@en
P2093
P2860
P1476
The recent medicinal chemistry ...... ase small molecule inhibitors.
@en
P2093
P2860
P304
P356
10.2174/092986710794182953
P577
2010-01-01T00:00:00Z