Temperature-sensitive vaccinia virus mutants identify a gene with an essential role in viral replication.
about
The genome of Melanoplus sanguinipes entomopoxvirusMembers of a novel family of mammalian protein kinases complement the DNA-negative phenotype of a vaccinia virus ts mutant defective in the B1 kinaseIdentification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5ROrigin-independent plasmid replication occurs in vaccinia virus cytoplasmic factories and requires all five known poxvirus replication factorsBarrier to Autointegration Factor (BANF1): interwoven roles in nuclear structure, genome integrity, innate immunity, stress responses and progeriaPoxvirus DNA replicationPoxviral B1 kinase overcomes barrier to autointegration factor, a host defense against virus replicationTyrosine phosphorylation of A17 during vaccinia virus infection: involvement of the H1 phosphatase and the F10 kinase.Clustered charge-to-alanine mutagenesis of the vaccinia virus H5 gene: isolation of a dominant, temperature-sensitive mutant with a profound defect in morphogenesisA protein kinase activity associated with Epstein-Barr virus BGLF4 phosphorylates the viral early antigen EA-D in vitro.Role of vaccinia virus A20R protein in DNA replication: construction and characterization of temperature-sensitive mutants.Regulation of viral intermediate gene expression by the vaccinia virus B1 protein kinase.Protein kinase Cδ regulates vaccinia-related kinase 1 in DNA damage-induced apoptosis.Evaluation of the role of the vaccinia virus uracil DNA glycosylase and A20 proteins as intrinsic components of the DNA polymerase holoenzyme.Barrier to auto integration factor becomes dephosphorylated during HSV-1 Infection and Can Act as a host defense by impairing viral DNA replication and gene expressionBiochemical and genetic analysis of the vaccinia virus d5 protein: Multimerization-dependent ATPase activity is required to support viral DNA replicationVaccinia protein kinase 2: a second essential serine/threonine protein kinase encoded by vaccinia virus.Vaccinia virus gene H5R encodes a protein that is phosphorylated by the multisubstrate vaccinia virus B1R protein kinase.The vaccinia virus D5 protein, which is required for DNA replication, is a nucleic acid-independent nucleoside triphosphatase.The vaccinia virus H5R gene encodes late gene transcription factor 4: purification, cloning, and overexpression.Mitotic histone H3 phosphorylation by vaccinia-related kinase 1 in mammalian cells.Genetic characterization of the vaccinia virus DNA polymerase: cytosine arabinoside resistance requires a variable lesion conferring phosphonoacetate resistance in conjunction with an invariant mutation localized to the 3'-5' exonuclease domain.African swine fever virus encodes a serine protein kinase which is packaged into virions.Genetic characterization of the vaccinia virus DNA polymerase: identification of point mutations conferring altered drug sensitivities and reduced fidelity.The vaccinia virus B1R gene product is a serine/threonine protein kinase.Vaccinia virus B1 kinase: phenotypic analysis of temperature-sensitive mutants and enzymatic characterization of recombinant proteins.Viral serine/threonine protein kinasesThe dual-specificity phosphatase encoded by vaccinia virus, VH1, is essential for viral transcription in vivo and in vitro.Characterization of the single-stranded DNA binding protein encoded by the vaccinia virus I3 gene.Deletion of the Vaccinia Virus B1 Kinase Reveals Essential Functions of This Enzyme Complemented Partly by the Homologous Cellular Kinase VRK2.Vaccinia Virus B1 Kinase Is Required for Postreplicative Stages of the Viral Life Cycle in a BAF-Independent Manner in U2OS Cells.Cell- and virus-mediated regulation of the barrier-to-autointegration factor's phosphorylation state controls its DNA binding, dimerization, subcellular localization, and antipoxviral activity.Barrier to autointegration factor (BAF) inhibits vaccinia virus intermediate transcription in the absence of the viral B1 kinase.Clustered charge-to-alanine mutagenesis of the vaccinia virus A20 gene: temperature-sensitive mutants have a DNA-minus phenotype and are defective in the production of processive DNA polymerase activity.Cidofovir inhibits genome encapsidation and affects morphogenesis during the replication of vaccinia virus.Inhibition of vaccinia virus replication by two small interfering RNAs targeting B1R and G7L genes and their synergistic combination with cidofovir.Adenosine N1-oxide inhibits vaccinia virus replication by blocking translation of viral early mRNAs.Temperature-sensitive mutants with lesions in the vaccinia virus F10 kinase undergo arrest at the earliest stage of virion morphogenesis.A poxvirus protein with a RING finger motif binds zinc and localizes in virus factories.Genetic and cell biological characterization of the vaccinia virus A30 and G7 phosphoproteins.
P2860
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P2860
Temperature-sensitive vaccinia virus mutants identify a gene with an essential role in viral replication.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Temperature-sensitive vaccinia ...... ial role in viral replication.
@ast
Temperature-sensitive vaccinia ...... ial role in viral replication.
@en
type
label
Temperature-sensitive vaccinia ...... ial role in viral replication.
@ast
Temperature-sensitive vaccinia ...... ial role in viral replication.
@en
prefLabel
Temperature-sensitive vaccinia ...... ial role in viral replication.
@ast
Temperature-sensitive vaccinia ...... ial role in viral replication.
@en
P2093
P2860
P1433
P1476
Temperature-sensitive vaccinia ...... tial role in viral replication
@en
P2093
M K Anderson
P Traktman
R E Rempel
P2860
P304
P407
P577
1990-02-01T00:00:00Z