Definition of the sequence requirements for binding of the EBNA-1 protein to its palindromic target sites in Epstein-Barr virus DNA
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Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic miceThe cellular proteins that bind specifically to the Epstein-Barr virus origin of plasmid DNA replication belong to a gene familyThe Role of Gammaherpesviruses in Cancer PathogenesisPotential cellular functions of Epstein-Barr Nuclear Antigen 1 (EBNA1) of Epstein-Barr VirusDiscovery of selective inhibitors against EBNA1 via high throughput in silico virtual screeningHuman RPA (hSSB) interacts with EBNA1, the latent origin binding protein of Epstein-Barr virusEpstein-Barr virus latency switch in human B-cells: a physico-chemical model.EBNA1 regulates cellular gene expression by binding cellular promotersDevelopment of a high-throughput screen for inhibitors of Epstein-Barr virus EBNA1.Epstein-Barr virus nuclear antigen 1 does not induce lymphoma in transgenic FVB mice.The Epstein-Barr virus major latent promoter Qp is constitutively active, hypomethylated, and methylation sensitiveFunctional analyses of the EBNA1 origin DNA binding protein of Epstein-Barr virus.The minimal replicator of Epstein-Barr virus oriP.Repression of Epstein-Barr virus EBNA-1 gene transcription by pRb during restricted latencyThe replicator of the Epstein-Barr virus latent cycle origin of DNA replication, oriP, is composed of multiple functional elements.DNA binding and modulation of gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirusEpstein-Barr nuclear antigen 1 binds and destabilizes nucleosomes at the viral origin of latent DNA replication.Epstein-Barr virus nuclear antigen 1 activates transcription from episomal but not integrated DNA and does not alter lymphocyte growthConstitutive binding of EBNA1 protein to the Epstein-Barr virus replication origin, oriP, with distortion of DNA structure during latent infection.The spacing between adjacent binding sites in the family of repeats affects the functions of Epstein-Barr nuclear antigen 1 in transcription activation and stable plasmid maintenanceHuman origin recognition complex binds to the region of the latent origin of DNA replication of Epstein-Barr virus.Functional dissection of latency-associated nuclear antigen 1 of Kaposi's sarcoma-associated herpesvirus involved in latent DNA replication and transcription of terminal repeats of the viral genome.Mitotic chromosome-binding activity of latency-associated nuclear antigen 1 is required for DNA replication from terminal repeat sequence of Kaposi's sarcoma-associated herpesvirusIdentification of a conserved non-protein-coding genomic element that plays an essential role in Alphabaculovirus pathogenesisCooperative assembly of EBNA1 on the Epstein-Barr virus latent origin of replicationLive-cell imaging reveals multiple interactions between Epstein-Barr virus nuclear antigen 1 and cellular chromatin during interphase and mitosisThe AT-hook DNA binding ability of the Epstein Barr virus EBNA1 protein is necessary for the maintenance of viral genomes in latently infected cells.Effect of number and position of EBNA-1 binding sites in Epstein-Barr virus oriP on the sites of initiation, barrier formation, and termination of replicationSeparation of the complex DNA binding domain of EBNA-1 into DNA recognition and dimerization subdomains of novel structure.EBNA1 can link the enhancer element to the initiator element of the Epstein-Barr virus plasmid origin of DNA replication.Reciprocal regulation of the Epstein-Barr virus BamHI-F promoter by EBNA-1 and an E2F transcription factor.The affinity of EBNA1 for its origin of DNA synthesis is a determinant of the origin's replicative efficiency.Functional domains of Epstein-Barr virus nuclear antigen EBNA-1.Interaction of Epstein-Barr virus nuclear antigen 1 with the viral latent origin of replication.EBNA1 distorts oriP, the Epstein-Barr virus latent replication origin.The Epstein-Barr virus nuclear protein 1 promoter active in type I latency is autoregulated.The plasmid replicon of Epstein-Barr virus: mechanistic insights into efficient, licensed, extrachromosomal replication in human cells.The Epstein-Barr virus Zta transactivator: a member of the bZIP family with unique DNA-binding specificity and a dimerization domain that lacks the characteristic heptad leucine zipper motif.Analysis of a replication initiation sequence from the adenosine deaminase region of the mouse genomeEpstein-Barr Nuclear Antigen 1 modulates replication of oriP-plasmids by impeding replication and transcription fork migration through the family of repeats.
P2860
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P2860
Definition of the sequence requirements for binding of the EBNA-1 protein to its palindromic target sites in Epstein-Barr virus DNA
description
1990 nî lūn-bûn
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1990年の論文
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1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
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1990年论文
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name
Definition of the sequence req ...... ites in Epstein-Barr virus DNA
@ast
Definition of the sequence req ...... ites in Epstein-Barr virus DNA
@en
type
label
Definition of the sequence req ...... ites in Epstein-Barr virus DNA
@ast
Definition of the sequence req ...... ites in Epstein-Barr virus DNA
@en
prefLabel
Definition of the sequence req ...... ites in Epstein-Barr virus DNA
@ast
Definition of the sequence req ...... ites in Epstein-Barr virus DNA
@en
P2093
P2860
P1433
P1476
Definition of the sequence req ...... ites in Epstein-Barr virus DNA
@en
P2093
D R Rawlins
G S Hayward
R F Ambinder
S D Hayward
P2860
P304
P407
P577
1990-05-01T00:00:00Z