Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth - Wikidata - awgldk - TriplyDB

Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

http://www.wikidata.org/entity/Q36807644

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Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism Di-(2-Ethylhexyl)-Phthalate (DEHP) Causes Impaired Adipocyte Function and Alters Serum Metabolites Vaspin inhibits kallikrein 7 by serpin mechanism Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity Morbid obesity attenuates the skeletal abnormalities associated with leptin deficiency in mice Hormone replacement therapy and physical function in healthy older men. Time to talk hormones?The Role of the Growth Hormone/Insulin-Like Growth Factor System in Visceral Adiposity.TSH compensates thyroid-specific IGF-I receptor knockout and causes papillary thyroid hyperplasia Elevated levels of insulin-like growth factor (IGF)-I in serum rescue the severe growth retardation of IGF-I null mice.Targeted deletion of somatotroph insulin-like growth factor-I signaling in a cell-specific knockout mouse model Insulin and insulin-like growth factor-1 receptors act as ligand-specific amplitude modulators of a common pathway regulating gene transcription.Divergent roles of growth factors in the GnRH regulation of puberty in mice.Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex.mTOR complex 2 in adipose tissue negatively controls whole-body growth Expression profiling of preadipocyte microRNAs by deep sequencing on chicken lines divergently selected for abdominal fatness.Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner.Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling.Weight Loss Upregulates the Small GTPase DIRAS3 in Human White Adipose Progenitor Cells, Which Negatively Regulates Adipogenesis and Activates Autophagy via Akt-mTOR Inhibition.Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.Adipocyte-released insulin-like growth factor-1 is regulated by glucose and fatty acids and controls breast cancer cell growth in vitro.Does the pituitary somatotrope play a primary role in regulating GH output in metabolic extremes?Lessons on conditional gene targeting in mouse adipose tissue Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.Relative growth hormone deficiency and cortisol excess are associated with increased cardiovascular risk markers in obese adolescent girls.Gut microbiota induce IGF-1 and promote bone formation and growth.Altered somatotroph feedback regulation improves metabolic efficiency and limits adipose deposition in male mice.Insulin growth factor binding proteins as therapeutic targets in type 2 diabetes.Macrophage and adipocyte IGF1 maintain adipose tissue homeostasis during metabolic stresses A Review of Cell-Based Strategies for Soft Tissue Reconstruction.Prenatal notch1 receptor blockade by protein delta homolog 1 (DLK1) modulates adipocyte size in vivo.Metabolic recovery of lipodystrophy, liver steatosis, and pancreatic β cell proliferation after the withdrawal of OSI-906.Differential organ phenotypes after postnatal Igf1r gene conditional deletion induced by tamoxifen in UBC-CreERT2; Igf1r fl/fl double transgenic mice.Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling.Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression.Gut Microbiota and IGF-1.Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin.Repin1 deficiency in adipose tissue improves whole-body insulin sensitivity, and lipid metabolism.

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P2860

Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

http://www.wikidata.org/entity/Q36807644

description

2008 nî lūn-bûn

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2008年の論文

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name

Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

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Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

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Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

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Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

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Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

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Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

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Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

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Karen Ruschke

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Matthias Kern

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Thomas Wunderlich

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Wilhelm Krone

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P2860

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

Expression and characterization of a functional human insulin-like growth factor I receptor

Extended longevity in mice lacking the insulin receptor in adipose tissue

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo.

Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance.

Minireview: tissue-specific versus generalized gene targeting of the igf1 and igf1r genes and their roles in insulin-like growth factor physiology.

Muscle-specific inactivation of the IGF-I receptor induces compensatory hyperplasia in skeletal muscle

Biology of insulin-like growth factors in development.

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2074-2082

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10.2337/DB07-1538

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8

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57

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Matthias Blüher

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2008-04-28T00:00:00Z

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5409576

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18443199

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2494689

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