The herpes simplex virus Us11 open reading frame encodes a sequence-specific RNA-binding protein
about
Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5A herpesvirus genetic element which affects translation in the absence of the viral GADD34 functionAssociation of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptidesBinding of herpes simplex virus-1 US11 to specific RNA sequencesThe C-terminal region but not the Arg-X-Pro repeat of Epstein-Barr virus protein EB2 is required for its effect on RNA splicing and transportThe herpes simplex virus US11 protein effectively compensates for the gamma1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2.RNAs extracted from herpes simplex virus 1 virions: apparent selectivity of viral but not cellular RNAs packaged in virions.Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1Herpes simplex virus tegument protein US11 interacts with conventional kinesin heavy chain.Epstein-Barr virus mRNA export factor EB2 is essential for production of infectious virus.In vivo replication of an ICP34.5 second-site suppressor mutant following corneal infection correlates with in vitro regulation of eIF2 alpha phosphorylation.The herpes simplex virus type 1 US11 protein binds the coterminal UL12, UL13, and UL14 RNAs and regulates UL13 expression in vivo.Structure and function in the herpes simplex virus 1 RNA-binding protein U(s)11: mapping of the domain required for ribosomal and nucleolar association and RNA binding in vitroAssemblons: nuclear structures defined by aggregation of immature capsids and some tegument proteins of herpes simplex virus 1Characterization of the products of the U(L)43 gene of herpes simplex virus 1: potential implications for regulation of gene expression by antisense transcriptionSuppression of the phenotype of gamma(1)34.5- herpes simplex virus 1: failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the alpha47 gene.Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis.A herpes simplex virus 1 US11-expressing cell line is resistant to herpes simplex virus infection at a step in viral entry mediated by glycoprotein DIdentification of a new transcriptional unit that yields a gene product within the unique sequences of the short component of the herpes simplex virus 1 genome.The herpes simplex virus 1 RNA binding protein US11 is a virion component and associates with ribosomal 60S subunitsHerpes simplex virus 1 RNA-binding protein US11 negatively regulates the accumulation of a truncated viral mRNA.Alternatively spliced mRNAs predicted to yield frame-shift proteins and stable intron 1 RNAs of the herpes simplex virus 1 regulatory gene alpha 0 accumulate in the cytoplasm of infected cells.Suppression of PACT-induced type I interferon production by herpes simplex virus 1 Us11 protein.Evolution and diversity in human herpes simplex virus genomes.HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation.Phosphorylation site mutations affect herpes simplex virus type 1 ICP0 function.Neurons versus herpes simplex virus: the innate immune interactions that contribute to a host-pathogen standoffExpression, purification of herpes simplex virus type 1 US11 protein, and production of US11 polyclonal antibody.Characterization of RNA determinants recognized by the arginine- and proline-rich region of Us11, a herpes simplex virus type 1-encoded double-stranded RNA binding protein that prevents PKR activation.RNA binding by the herpes simplex virus type 1 nucleocytoplasmic shuttling protein UL47 is mediated by an N-terminal arginine-rich domain that also functions as its nuclear localization signal.A conserved carboxy-terminal domain in the major tegument structural protein VP22 facilitates virion packaging of a chimeric protein during productive herpes simplex virus 1 infection.Herpes Simplex Virus 1 Inhibits TANK-Binding Kinase 1 through Formation of the Us11-Hsp90 Complex.
P2860
Q24304261-75AFC2F3-3649-4432-8158-062D80AE35C4Q24562045-C378B6B6-9E02-42E1-95A5-A83BD5A3917CQ24683333-EBB2B447-0A81-44C4-885E-8949CD0E36DCQ24816239-142DC779-63AB-4D63-A34A-1F1843BF1FC4Q33647481-6132B9D9-7E4D-4C80-964F-45EB061F0A0EQ33785225-8BDD0B38-83E8-46DF-AF3E-000BCFD7E4B5Q33853688-ADA54790-FB57-493E-BCF3-06D97B85DEEDQ34302130-E1A0DE19-EAB8-419B-8BB0-4FEEB48A0DF1Q34333855-728D15B7-07F6-4BC0-9603-2B21CF20F1FEQ34347652-3A15352F-F8B7-4391-B9B9-EAC5C8D7964CQ34858111-E4EF6113-5FE3-43FC-91F4-F2C3BA8BF473Q35000995-66D26E2B-E57E-4C25-B0A0-4AD434DC55A8Q35859934-26A57DD0-6C4C-4C43-AB61-5639F2E34CB5Q35864562-2C53ED6C-7C39-4050-B4E5-B98198357DA0Q35871964-B8104F51-5A34-4C09-AB63-5379C0535FF3Q35890099-A053AB98-4A8C-4CB6-B8D4-B2ABA97AA05EQ36350435-FC271780-65D0-40A3-BB40-0A99ECACE062Q36633169-42F0DAB8-5EFF-4564-966B-7CECF35641ABQ36649937-FDAA4065-4897-4E9A-8B00-0AB10AE1CDD3Q36698109-C64DF85C-71E3-4E97-B596-CE1B2FD1E0F7Q36820840-32B870A2-BAB0-484F-869B-137B3DB1F166Q37242656-620E4FBD-017E-477A-8025-6E85D266CD6CQ37336854-7E8257B4-08CB-421C-87F0-57A65697D283Q37547447-6DFAD618-9FB6-4BF6-B8D2-00D635C29383Q37571288-CD508499-B058-4485-BE63-F5A20C854B16Q37743081-A968F5E4-8664-41EF-AED0-F32FBCFBCF00Q38554939-51F251DC-A7DF-42A1-8079-8D898A9C2E74Q39157648-97C7915D-197A-4427-9498-20517ACC44F5Q39686292-69320549-5C04-4664-8376-9A88B4402E00Q40196922-8329EC16-112D-4C83-B2C7-4A1F056EFDCEQ42065188-2B42D0CE-C8F8-47D1-A523-743A9263C57FQ54111191-13BC96DA-18DA-4BCD-9FD5-1C2E9775DD92
P2860
The herpes simplex virus Us11 open reading frame encodes a sequence-specific RNA-binding protein
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
The herpes simplex virus Us11 ...... e-specific RNA-binding protein
@ast
The herpes simplex virus Us11 ...... e-specific RNA-binding protein
@en
type
label
The herpes simplex virus Us11 ...... e-specific RNA-binding protein
@ast
The herpes simplex virus Us11 ...... e-specific RNA-binding protein
@en
prefLabel
The herpes simplex virus Us11 ...... e-specific RNA-binding protein
@ast
The herpes simplex virus Us11 ...... e-specific RNA-binding protein
@en
P2860
P1433
P1476
The herpes simplex virus Us11 ...... e-specific RNA-binding protein
@en
P2093
R J Roller
P2860
P304
P407
P577
1990-07-01T00:00:00Z