The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection.
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Herpes simplex virus IE63 (ICP27) protein interacts with spliceosome-associated protein 145 and inhibits splicing prior to the first catalytic stepMolecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine.Herpes simplex virus type 1 immediate-early protein ICP27 is required for efficient incorporation of ICP0 and ICP4 into virionsBovine Herpes Virus 1 (BHV-1) and Herpes Simplex Virus Type 1 (HSV-1) Promote Survival of Latently Infected Sensory Neurons, in Part by Inhibiting ApoptosisHerpes simplex virus type 1 entry is inhibited by the cobalt chelate complex CTC-96Mta has properties of an RNA export protein and increases cytoplasmic accumulation of Epstein-Barr virus replication gene mRNA.Isolation and characterization of a functional cDNA encoding ICP0 from herpes simplex virus type 1Analysis of the phosphorylation sites of herpes simplex virus type 1 regulatory protein ICP27.Towards an understanding of the herpes simplex virus type 1 latency-reactivation cycleRegulation of viral gene expression by duck enteritis virus UL54.Control of VP16 translation by the herpes simplex virus type 1 immediate-early protein ICP27.HSV-1 ICP27 induces apoptosis by promoting Bax translocation to mitochondria through interacting with 14-3-3θ.HSV-1 ICP27 represses NF-κB activity by regulating Daxx sumoylationPersistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins.Herpesvirus mRNAs are sorted for export via Crm1-dependent and -independent pathwaysHerpes simplex virus ICP27 induces cytoplasmic accumulation of unspliced polyadenylated alpha-globin pre-mRNA in infected HeLa cells.Processing of alpha-globin and ICP0 mRNA in cells infected with herpes simplex virus type 1 ICP27 mutants.The conserved carboxyl-terminal half of herpes simplex virus type 1 regulatory protein ICP27 is dispensable for viral growth in the presence of compensatory mutationsAccumulation of herpes simplex virus type 1 early and leaky-late proteins correlates with apoptosis prevention in infected human HEp-2 cells.Identification and transcriptional analyses of the UL3 and UL4 genes of equine herpesvirus 1, homologs of the ICP27 and glycoprotein K genes of herpes simplex virus.HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part I. HSV-1 structure, replication and pathogenesis.UL54-null pseudorabies virus is attenuated in mice but productively infects cells in cultureDirect stimulation of translation by the multifunctional herpesvirus ICP27 protein.Mapping of functional regions in the amino-terminal portion of the herpes simplex virus ICP27 regulatory protein: importance of the leucine-rich nuclear export signal and RGG Box RNA-binding domain.Herpes simplex virus type 1 and bovine herpesvirus 1 latency.Barrier to auto integration factor becomes dephosphorylated during HSV-1 Infection and Can Act as a host defense by impairing viral DNA replication and gene expressionMultiple roles of Epstein-Barr virus SM protein in lytic replication.Intracellular localization of the herpes simplex virus type 1 major transcriptional regulatory protein, ICP4, is affected by ICP27Evaluation of colocalization interactions between the IE110, IE175, and IE63 transactivator proteins of herpes simplex virus within subcellular punctate structuresRegulatory function of the equine herpesvirus 1 ICP27 gene product.Arginine-rich regions succeeding the nuclear localization region of the herpes simplex virus type 1 regulatory protein ICP27 are required for efficient nuclear localization and late gene expressionFunctional interactions between herpes simplex virus immediate-early proteins during infection: gene expression as a consequence of ICP27 and different domains of ICP4.The C-terminal repressor region of herpes simplex virus type 1 ICP27 is required for the redistribution of small nuclear ribonucleoprotein particles and splicing factor SC35; however, these alterations are not sufficient to inhibit host cell splicinAn activity specified by the osteosarcoma line U2OS can substitute functionally for ICP0, a major regulatory protein of herpes simplex virus type 1Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis.Herpes simplex virus trans-regulatory protein ICP27 stabilizes and binds to 3' ends of labile mRNA.Herpes simplex ICP27 mutant viruses exhibit reduced expression of specific DNA replication genesOverexpression of the herpes simplex virus type 1 immediate-early regulatory protein, ICP27, is responsible for the aberrant localization of ICP0 and mutant forms of ICP4 in ICP4 mutant virus-infected cells.Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22.Human cytomegalovirus tegument protein pp71 (ppUL82) enhances the infectivity of viral DNA and accelerates the infectious cycle.
P2860
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P2860
The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
The repressing and enhancing f ...... ssion very early in infection.
@ast
The repressing and enhancing f ...... ssion very early in infection.
@en
type
label
The repressing and enhancing f ...... ssion very early in infection.
@ast
The repressing and enhancing f ...... ssion very early in infection.
@en
prefLabel
The repressing and enhancing f ...... ssion very early in infection.
@ast
The repressing and enhancing f ...... ssion very early in infection.
@en
P2860
P1433
P1476
The repressing and enhancing f ...... ssion very early in infection.
@en
P2093
P A Schaffer
P2860
P304
P407
P577
1990-07-01T00:00:00Z