Arginine-rich regions succeeding the nuclear localization region of the herpes simplex virus type 1 regulatory protein ICP27 are required for efficient nuclear localization and late gene expression
about
Land use, macroalgae, and a tumor-forming disease in marine turtlesICP27 interacts with the RNA export factor Aly/REF to direct herpes simplex virus type 1 intronless mRNAs to the TAP export pathway.Discovery of a novel single-stranded DNA virus from a sea turtle fibropapilloma by using viral metagenomicsMta has properties of an RNA export protein and increases cytoplasmic accumulation of Epstein-Barr virus replication gene mRNA.Hsc70 focus formation at the periphery of HSV-1 transcription sites requires ICP27.Analysis of the phosphorylation sites of herpes simplex virus type 1 regulatory protein ICP27.ICP27 phosphorylation site mutants display altered functional interactions with cellular export factors Aly/REF and TAP/NXF1 but are able to bind herpes simplex virus 1 RNAICP27 recruits Aly/REF but not TAP/NXF1 to herpes simplex virus type 1 transcription sites although TAP/NXF1 is required for ICP27 export.Human circovirus TT virus genotype 6 expresses six proteins following transfection of a full-length cloneThe adenovirus E4-6/7 protein directs nuclear localization of E2F-4 via an arginine-rich motif.The human herpesvirus 8 homolog of Epstein-Barr virus SM protein (KS-SM) is a posttranscriptional activator of gene expressionIdentification of an export control sequence and a requirement for the KH domains in ICP27 from herpes simplex virus type 1Accumulation of herpes simplex virus type 1 early and leaky-late proteins correlates with apoptosis prevention in infected human HEp-2 cells.Epstein-Barr virus SM protein interacts with mRNA in vivo and mediates a gene-specific increase in cytoplasmic mRNA.Nucleolar localization elements in U8 snoRNA differ from sequences required for rRNA processingFunctional analysis of Epstein-Barr virus SM protein: identification of amino acids essential for structure, transactivation, splicing inhibition, and virion productionArginine methylation of the RGG box does not appear to regulate ICP27 import during herpes simplex virus infection.ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motifProtein arginine methyltransferase 1-directed methylation of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen.Multiple roles of Epstein-Barr virus SM protein in lytic replication.The C-terminal repressor region of herpes simplex virus type 1 ICP27 is required for the redistribution of small nuclear ribonucleoprotein particles and splicing factor SC35; however, these alterations are not sufficient to inhibit host cell splicinThe herpes simplex virus type 1 regulatory protein ICP27 coimmunoprecipitates with anti-Sm antiserum, and the C terminus appears to be required for this interactionHerpes simplex ICP27 mutant viruses exhibit reduced expression of specific DNA replication genesThe RGG box motif of the herpes simplex virus ICP27 protein mediates an RNA-binding activity and determines in vivo methylation.The structure of the folded domain from the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer.Critical role for arginine methylation in adenovirus-infected cells.Herpes simplex virus ICP27 increases translation of a subset of viral late mRNAs.Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing.A SUMO-targeted ubiquitin ligase is involved in the degradation of the nuclear pool of the SUMO E3 ligase Siz1.Global analysis of herpes simplex virus type 1 transcription using an oligonucleotide-based DNA microarray.The immediate-early gene product encoded by open reading frame 57 of herpesvirus saimiri modulates gene expression at a posttranscriptional level.The open reading frame (ORF) 50a gene product regulates ORF 57 gene expression in herpesvirus saimiri.The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylationCytoplasm-to-nucleus translocation of a herpesvirus tegument protein during cell divisionThe open reading frame 57 gene product of herpesvirus saimiri shuttles between the nucleus and cytoplasm and is involved in viral RNA nuclear export.ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation.Regulation of herpes simplex virus poly (A) site usage and the action of immediate-early protein IE63 in the early-late switch.Herpes simplex virus type 1 protein IE63 affects the nuclear export of virus intron-containing transcripts.Immediate-early expression of the herpes simplex virus type 1 ICP27 transcript is not critical for efficient replication in vitro or in vivoShuttling of the herpes simplex virus type 1 regulatory protein ICP27 between the nucleus and cytoplasm mediates the expression of late proteins.
P2860
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P2860
Arginine-rich regions succeeding the nuclear localization region of the herpes simplex virus type 1 regulatory protein ICP27 are required for efficient nuclear localization and late gene expression
description
1995 nî lūn-bûn
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1995年の論文
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1995年学术文章
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1995年学术文章
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name
Arginine-rich regions succeedi ...... ation and late gene expression
@ast
Arginine-rich regions succeedi ...... ation and late gene expression
@en
type
label
Arginine-rich regions succeedi ...... ation and late gene expression
@ast
Arginine-rich regions succeedi ...... ation and late gene expression
@en
prefLabel
Arginine-rich regions succeedi ...... ation and late gene expression
@ast
Arginine-rich regions succeedi ...... ation and late gene expression
@en
P2860
P1433
P1476
Arginine-rich regions succeedi ...... ation and late gene expression
@en
P2093
M K Hibbard
R M Sandri-Goldin
P2860
P304
P407
P577
1995-08-01T00:00:00Z