E2A expression, nuclear localization, and in vivo formation of DNA- and non-DNA-binding species during B-cell development.
about
Fetal Alz-50 clone 1, a novel zinc finger protein, binds a specific DNA sequence and acts as a transcriptional regulatorPhosphorylation of E47 as a potential determinant of B-cell-specific activityHelix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cellsB-cell-specific DNA binding by an E47 homodimerGradient of E2A activity in B-cell development.Novel regulation of the helix-loop-helix protein Id1 by S5a, a subunit of the 26 S proteasomeMeis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteinsIdentification of the E2A gene products as regulatory targets of the G1 cyclin-dependent kinases.Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic miceGenomic cloning and promoter analysis of aortic preferentially expressed gene-1. Identification of a vascular smooth muscle-specific promoter mediated by an E box motif.Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system.Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability.Restricted expression of E2A protein in primary human tissues correlates with proliferation and differentiation.Various modes of basic helix-loop-helix protein-mediated regulation of murine leukemia virus transcription in lymphoid cell lines.Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus.The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis.Regulation of the pro-B-cell-specific enhancer of the Id1 gene involves the C/EBP family of proteins.Pan/E2A expression precedes immunoglobulin heavy-chain expression during B lymphopoiesis in nontransformed cells, and Pan/E2A proteins are not detected in myeloid cellsInduction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1Displacement of an E-box-binding repressor by basic helix-loop-helix proteins: implications for B-cell specificity of the immunoglobulin heavy-chain enhancer.Transformation of bone marrow B-cell progenitors by E2a-Hlf requires coexpression of Bcl-2.Substitution of basic amino acids in the basic region stabilizes DNA binding by E12 homodimersIdentification of cyclin D3 as a direct target of E2A using DamID.Pod1 induces myofibroblast differentiation in mesenchymal progenitor cells from mouse kidney.ABCB1 over-expression and drug-efflux in acute lymphoblastic leukemia cell lines with t(17;19) and E2A-HLF expression.Hematopoietic lineage commitment: role of transcription factors.Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable.Basic helix-loop-helix proteins in murine type C retrovirus transcriptional regulation.Repression of the immunoglobulin heavy chain 3' enhancer by helix-loop-helix protein Id3 via a functionally important E47/E12 binding site: implications for developmental control of enhancer function.SETDB2 Links E2A-PBX1 to Cell-Cycle Dysregulation in Acute Leukemia through CDKN2C Repression.
P2860
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P2860
E2A expression, nuclear localization, and in vivo formation of DNA- and non-DNA-binding species during B-cell development.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
E2A expression, nuclear locali ...... ies during B-cell development.
@en
type
label
E2A expression, nuclear locali ...... ies during B-cell development.
@en
prefLabel
E2A expression, nuclear locali ...... ies during B-cell development.
@en
P2093
P2860
P356
P1476
E2A expression, nuclear locali ...... ies during B-cell development.
@en
P2093
P2860
P304
P356
10.1128/MCB.13.12.7321
P407
P577
1993-12-01T00:00:00Z