Carboxyl-terminal determinants of Abelson protein important for lymphoma induction.
about
Mutations affecting the MA portion of the v-Abl protein reveal a conserved role of Gag in Abelson murine leukemia virus (MLV) and Moloney MLVp53 mediates apoptotic crisis in primary Abelson virus-transformed pre-B cells.p53 deficiency increases transformation by v-Abl and rescues the ability of a C-terminally truncated v-Abl mutant to induce pre-B lymphoma in vivo.Decreased virus population diversity in p53-null mice infected with weakly oncogenic Abelson virus.The extreme carboxyl terminus of v-Abl is required for lymphoid cell transformation by Abelson virus.Gag influences transformation by Abelson murine leukemia virus and suppresses nuclear localization of the v-Abl proteinBCR-ABL and v-abl oncogenes induce distinct patterns of thymic lymphoma involving different lymphocyte subsets.Ras complements the carboxyl terminus of v-Abl protein in lymphoid transformation.An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia chromosome-positive human leukemias
P2860
Q28754439-B2396D87-2682-4765-AEF3-EA3F17772E94Q33958575-AE8FCD23-D428-4FA2-92DF-2A63106FC076Q33961551-95785B1C-9F7B-4AD4-A1AD-1B6A53D79AD1Q33987503-D3FF8853-BF2A-49E4-953A-D9E9C0623AB9Q34859191-BF3CB3D0-1813-4B36-B43B-D395D6FA81B5Q35947927-F51D6CD7-5E50-435E-BF0C-3AD787E22B63Q36653547-D2BE0416-0880-4D0A-80F4-48B45D1CD4CEQ38362429-0430F499-F5BF-4A4F-8260-B777EBAB6144Q40872589-AA11AFC3-259B-44AC-B4B0-CEBEFDEA1406
P2860
Carboxyl-terminal determinants of Abelson protein important for lymphoma induction.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Carboxyl-terminal determinants of Abelson protein important for lymphoma induction.
@en
type
label
Carboxyl-terminal determinants of Abelson protein important for lymphoma induction.
@en
prefLabel
Carboxyl-terminal determinants of Abelson protein important for lymphoma induction.
@en
P2093
P2860
P1433
P1476
Carboxyl-terminal determinants of Abelson protein important for lymphoma induction.
@en
P2093
N Rosenberg
R C Huebner
P2860
P304
P407
P577
1991-12-01T00:00:00Z