Herpes simplex virus type 1 immediate-early protein Vmw110 reactivates latent herpes simplex virus type 2 in an in vitro latency system.
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ICP0 antagonizes ICP4-dependent silencing of the herpes simplex virus ICP0 geneFunctional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory proteinA novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory proteinHerpes simplex virus latency-associated transcript is a stable intronFunctional inaccessibility of quiescent herpes simplex virus genomesThe molecular basis of herpes simplex virus latencyHSV-1 ICP0: paving the way for viral replicationIsolation and characterization of a functional cDNA encoding ICP0 from herpes simplex virus type 1Role of nuclear factor Y in stress-induced activation of the herpes simplex virus type 1 ICP0 promoterICP0 induces the accumulation of colocalizing conjugated ubiquitin.Herpes simplex virus tegument ICP0 is capsid associated, and its E3 ubiquitin ligase domain is important for incorporation into virions.Herpes simplex virus VP16, but not ICP0, is required to reduce histone occupancy and enhance histone acetylation on viral genomes in U2OS osteosarcoma cells.Genetic studies exposing the splicing events involved in herpes simplex virus type 1 latency-associated transcript production during lytic and latent infection.Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins.Persistence and expression of the herpes simplex virus genome in the absence of immediate-early proteins.The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoformsOptimized viral dose and transient immunosuppression enable herpes simplex virus ICP0-null mutants To establish wild-type levels of latency in vivo.Murine gammaherpesvirus 68 cyclin D homologue is required for efficient reactivation from latency.Truncation of the C-terminal acidic transcriptional activation domain of herpes simplex virus VP16 renders expression of the immediate-early genes almost entirely dependent on ICP0Role of herpes simplex virus ICP0 in the transactivation of genes introduced by infection or transfection: a reappraisal.ICP0 is required for efficient reactivation of herpes simplex virus type 1 from neuronal latency.Efficient activation of viral genomes by levels of herpes simplex virus ICP0 insufficient to affect cellular gene expression or cell survival.ICP0, ICP4, or VP16 expressed from adenovirus vectors induces reactivation of latent herpes simplex virus type 1 in primary cultures of latently infected trigeminal ganglion cells.Novel roles of cytoplasmic ICP0: proteasome-independent functions of the RING finger are required to block interferon-stimulated gene production but not to promote viral replication.Rapid in vivo reactivation of herpes simplex virus in latently infected murine ganglionic neurons after transient hyperthermia.Herpes latency, meningitis, radiculomyelopathy and disseminated infection.The cellular localization pattern of Varicella-Zoster virus ORF29p is influenced by proteasome-mediated degradationThe cyclin-dependent kinase inhibitor roscovitine inhibits the transactivating activity and alters the posttranslational modification of herpes simplex virus type 1 ICP0.HSV-1 genome subnuclear positioning and associations with host-cell PML-NBs and centromeres regulate LAT locus transcription during latency in neurons.ICP0 is not required for efficient stress-induced reactivation of herpes simplex virus type 1 from cultured quiescently infected neuronal cells.The herpes simplex virus immediate-early ubiquitin ligase ICP0 induces degradation of the ICP0 repressor protein E2FBP1.Herpes simplex virus ICP0 promotes both histone removal and acetylation on viral DNA during lytic infection.Experimental investigation of herpes simplex virus latencyDevelopment of a novel cell-based assay to monitor the transactivation activity of the HSV-1 protein ICP0.Evaluation of colocalization interactions between the IE110, IE175, and IE63 transactivator proteins of herpes simplex virus within subcellular punctate structuresExtracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency.An activity specified by the osteosarcoma line U2OS can substitute functionally for ICP0, a major regulatory protein of herpes simplex virus type 1Attenuation of DNA-dependent protein kinase activity and its catalytic subunit by the herpes simplex virus type 1 transactivator ICP0.Herpes simplex virus immediate-early proteins ICP0 and ICP4 activate the endogenous human alpha-globin gene in nonerythroid cells.
P2860
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P2860
Herpes simplex virus type 1 immediate-early protein Vmw110 reactivates latent herpes simplex virus type 2 in an in vitro latency system.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Herpes simplex virus type 1 im ...... in an in vitro latency system.
@en
type
label
Herpes simplex virus type 1 im ...... in an in vitro latency system.
@en
prefLabel
Herpes simplex virus type 1 im ...... in an in vitro latency system.
@en
P2093
P2860
P1433
P1476
Herpes simplex virus type 1 im ...... in an in vitro latency system.
@en
P2093
C M Preston
R A Harris
R D Everett
S Silverstein
P2860
P304
P407
P577
1989-08-01T00:00:00Z