Murine gammaherpesvirus 68 cyclin D homologue is required for efficient reactivation from latency.
about
Viral cyclins mediate separate phases of infection by integrating functions of distinct mammalian cyclinsA gammaherpesviral internal repeat contributes to latency amplification.Induction of protective immunity against murine gammaherpesvirus 68 infection in the absence of viral latency.Ex vivo stimulation of B cells latently infected with gammaherpesvirus 68 triggers reactivation from latencySimian homologues of human herpesvirus 8Activation of the Kaposi's sarcoma-associated herpesvirus major latency locus by the lytic switch protein RTA (ORF50).Viral latency and its regulation: lessons from the gamma-herpesviruses.Evolutionary aspects of oncogenic herpesvirusesGamma interferon blocks gammaherpesvirus reactivation from latency.The cyclin-dependent kinase inhibitor roscovitine inhibits the transactivating activity and alters the posttranslational modification of herpes simplex virus type 1 ICP0.Persistent gamma-herpesvirus infections: what can we learn from an experimental mouse model?Maintenance of gammaherpesvirus latency requires viral cyclin in the absence of B lymphocytes.The latency-associated nuclear antigen homolog of herpesvirus saimiri inhibits lytic virus replication.Mechanisms of Kaposi's Sarcoma-Associated Herpesvirus Latency and ReactivationSelective gene expression of latent murine gammaherpesvirus 68 in B lymphocytes.Evidence for CDK-dependent and CDK-independent functions of the murine gammaherpesvirus 68 v-cyclin.A Conserved Gammaherpesvirus Cyclin Specifically Bypasses Host p18(INK4c) To Promote Reactivation from Latency.A secreted chemokine binding protein encoded by murine gammaherpesvirus-68 is necessary for the establishment of a normal latent load.Identification of the in vivo role of a viral bcl-2Gamma-herpesvirus latency is preferentially maintained in splenic germinal center and memory B cellsH2AX phosphorylation is important for LANA-mediated Kaposi's sarcoma-associated herpesvirus episome persistence.Identification of an Rta responsive promoter involved in driving gammaHV68 v-cyclin expression during virus replication.Murine gammaherpesvirus 68 infection of gamma interferon-deficient mice on a BALB/c background results in acute lethal pneumonia that is dependent on specific viral genes.Cyclin-cyclin-dependent kinase regulatory response is linked to substrate recognition.The human cytomegalovirus UL82 gene product (pp71) accelerates progression through the G1 phase of the cell cycle.Critical role for a high-affinity chemokine-binding protein in gamma-herpesvirus-induced lethal meningitisCritical role of CD4 T cells in an antibody-independent mechanism of vaccination against gammaherpesvirus latency.Independence of herpesvirus-induced T cell lymphoma from viral cyclin D homologue.Host Tumor Suppressor p18INK4c functions as a potent cell-intrinsic inhibitor of γHV68 reactivation and pathogenesis.
P2860
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P2860
Murine gammaherpesvirus 68 cyclin D homologue is required for efficient reactivation from latency.
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2000 nî lūn-bûn
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name
Murine gammaherpesvirus 68 cyc ...... ent reactivation from latency.
@ast
Murine gammaherpesvirus 68 cyc ...... ent reactivation from latency.
@en
type
label
Murine gammaherpesvirus 68 cyc ...... ent reactivation from latency.
@ast
Murine gammaherpesvirus 68 cyc ...... ent reactivation from latency.
@en
prefLabel
Murine gammaherpesvirus 68 cyc ...... ent reactivation from latency.
@ast
Murine gammaherpesvirus 68 cyc ...... ent reactivation from latency.
@en
P2093
P2860
P1433
P1476
Murine gammaherpesvirus 68 cyc ...... ent reactivation from latency.
@en
P2093
P2860
P304
P356
10.1128/JVI.74.15.7016-7023.2000
P577
2000-08-01T00:00:00Z