Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling comp
about
The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycleClinical significance of T cell metabolic reprogramming in cancerThe Nrf2/HO-1 Axis in Cancer Cell Growth and ChemoresistanceDietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC InhibitionEpigenetic regulation of Keap1-Nrf2 signalingReactive oxygen production induced by the gut microbiota: pharmacotherapeutic implicationsSmall molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agentsCoordinated regulation of Nrf2 and histone H3 serine 10 phosphorylation in arsenite-activated transcription of the human heme oxygenase-1 geneThe Keap1-Nrf2 system in cancers: stress response and anabolic metabolismMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseaseEffect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liverHDAC inhibitors increase NRF2-signaling in tumour cells and blunt the efficacy of co-adminstered cytotoxic agentsOrganic extracts from African dust storms stimulate oxidative stress and induce inflammatory responses in human lung cells through Nrf2 but not NF-κBIndividual expression features of GPX2, NQO1 and SQSTM1 transcript variants induced by hydrogen peroxide treatment in HeLa cells.Robust selection of cancer survival signatures from high-throughput genomic data using two-fold subsamplingTranscriptome profiles of carcinoma-in-situ and invasive non-small cell lung cancer as revealed by SAGEPirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium.The Activity of SN33638, an Inhibitor of AKR1C3, on Testosterone and 17β-Estradiol Production and Function in Castration-Resistant Prostate Cancer and ER-Positive Breast Cancer.Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of actionHigh levels of Nrf2 determine chemoresistance in type II endometrial cancerNrf2 null enhances UVB-induced skin inflammation and extracellular matrix damages.Glucose reintroduction triggers the activation of Nrf2 during experimental ischemia reperfusion.Differential modulation of keratin expression by sulforaphane occurs via Nrf2-dependent and -independent pathways in skin epithelia.Targeting nrf2 signaling to combat chemoresistance.The role of miR-34a in the hepatoprotective effect of hydrogen sulfide on ischemia/reperfusion injury in young and old rats.Nitric oxide storage and transport in cells are mediated by glutathione S-transferase P1-1 and multidrug resistance protein 1 via dinitrosyl iron complexes.Optimization of fluorescently labeled Nrf2 peptide probes and the development of a fluorescence polarization assay for the discovery of inhibitors of Keap1-Nrf2 interaction.Metabolism of [6]-shogaol in mice and in cancer cells.Biological role of aldo-keto reductases in retinoic Acid biosynthesis and signaling.4-Acetoxyphenol Prevents RPE Oxidative Stress-Induced Necrosis by Functioning as an NRF2 Stabilizer.Pre-clinical activity of PR-104 as monotherapy and in combination with sorafenib in hepatocellular carcinoma.NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies.Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity.UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesisAn integrative approach for the identification of prognostic and predictive biomarkers in rectal cancerAberrant Keap1 methylation in breast cancer and association with clinicopathological features.Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles.Bach1 Induces Endothelial Cell Apoptosis and Cell-Cycle Arrest through ROS Generation.MicroRNA-93 regulates NRF2 expression and is associated with breast carcinogenesis.Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma.
P2860
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P2860
Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling comp
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Characterization of the cancer ...... as well as redox-cycling comp
@en
type
label
Characterization of the cancer ...... as well as redox-cycling comp
@en
prefLabel
Characterization of the cancer ...... as well as redox-cycling comp
@en
P2093
P2860
P50
P356
P1433
P1476
Characterization of the cancer ...... as well as redox-cycling comp
@en
P2093
A Kenneth MacLeod
Larry G Higgins
Simon M Plummer
P2860
P304
P356
10.1093/CARCIN/BGP176
P407
P577
2009-07-16T00:00:00Z