Role of interfacial amino acid residues in assembly, stability, and conformation of a spherical virus capsid.
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Packaging capacity of adeno-associated virus serotypes: impact of larger genomes on infectivity and postentry steps.Structural Characterization of H-1 Parvovirus: Comparison of Infectious Virions to Empty CapsidsVirulent variants emerging in mice infected with the apathogenic prototype strain of the parvovirus minute virus of mice exhibit a capsid with low avidity for a primary receptor.Intra- and inter-subunit disulfide bond formation is nonessential in adeno-associated viral capsidsVP2 cleavage and the leucine ring at the base of the fivefold cylinder control pH-dependent externalization of both the VP1 N terminus and the genome of minute virus of mice.Mechanical disassembly of single virus particles reveals kinetic intermediates predicted by theory.Dynamic pathways for viral capsid assemblyAnalysis of SAT type foot-and-mouth disease virus capsid proteins and the identification of putative amino acid residues affecting virus stability.Synonymous mutations reduce genome compactness in icosahedral ssRNA viruses.DNA-mediated anisotropic mechanical reinforcement of a virus.A theoretical model for the dynamic structure of hepatitis B nucleocapsidMutations at the base of the icosahedral five-fold cylinders of minute virus of mice induce 3'-to-5' genome uncoating and critically impair entry functions.Langevin dynamics simulation of polymer-assisted virus-like assembly.Tyrosine cross-linking reveals interfacial dynamics in adeno-associated viral capsids during infectionMechanical elasticity as a physical signature of conformational dynamics in a virus particleManipulation of the mechanical properties of a virus by protein engineering.Rational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditionsVirus engineering: functionalization and stabilization.Three-dimensional structure of foot-and-mouth disease virus and its biological functions.Cryo-EM maps reveal five-fold channel structures and their modification by gatekeeper mutations in the parvovirus minute virus of mice (MVM) capsid.Structural basis for biologically relevant mechanical stiffening of a virus capsid by cavity-creating or spacefilling mutations.SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased ThermostabilityAAV-ID: A Rapid and Robust Assay for Batch-to-Batch Consistency Evaluation of AAV Preparations.A slender tract of glycine residues is required for translocation of the VP2 protein N-terminal domain through the parvovirus MVM capsid channel to initiate infection.Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus.Viral oncolysis that targets Raf-1 signaling control of nuclear transport.Systematic study of the genetic response of a variable virus to the introduction of deleterious mutations in a functional capsid region.Engineering viable foot-and-mouth disease viruses with increased thermostability as a step in the development of improved vaccines.Nuclear export of the nonenveloped parvovirus virion is directed by an unordered protein signal exposed on the capsid surface.Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions.Deterministic, compensatory mutational events in the capsid of foot-and-mouth disease virus in response to the introduction of mutations found in viruses from persistent infections.Structural Analysis of a Temperature-Induced Transition in a Viral Capsid Probed by HDX-MS.Functional relevance of amino acid residues involved in interactions with ordered nucleic acid in a spherical virus.Mutational analysis of narrow pores at the fivefold symmetry axes of adeno-associated virus type 2 capsids reveals a dual role in genome packaging and activation of phospholipase A2 activityExpression and subcellular targeting of canine parvovirus capsid proteins in baculovirus-transduced NLFK cells.Visualization of the externalized VP2 N termini of infectious human parvovirus B19.Quantitatively probing propensity for structural transitions in engineered virus nanoparticles by single-molecule mechanical analysis.Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assemblyProtoparvovirus Cell Entry.Beyond icosahedral symmetry in packings of proteins in spherical shells.
P2860
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P2860
Role of interfacial amino acid residues in assembly, stability, and conformation of a spherical virus capsid.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Role of interfacial amino acid ...... n of a spherical virus capsid.
@en
type
label
Role of interfacial amino acid ...... n of a spherical virus capsid.
@en
prefLabel
Role of interfacial amino acid ...... n of a spherical virus capsid.
@en
P2093
P2860
P356
P1476
Role of interfacial amino acid ...... n of a spherical virus capsid.
@en
P2093
Aura Carreira
José María Almendral
Juan Reguera
Laura Riolobos
Mauricio G Mateu
P2860
P304
P356
10.1073/PNAS.0307748101
P407
P577
2004-02-23T00:00:00Z