RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells.
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The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNSDesigning siRNA that distinguish between genes that differ by a single nucleotideBrain site-specific gene expression analysis in Alzheimer's disease patients.Enhancement of allele discrimination by introduction of nucleotide mismatches into siRNA in allele-specific gene silencing by RNAi.Nuclear export of misfolded SOD1 mediated by a normally buried NES-like sequence reduces proteotoxicity in the nucleus.A high-throughput screen to identify inhibitors of SOD1 transcription.Neuroprotection for amyotrophic lateral sclerosis: role of stem cells, growth factors, and gene therapy.Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis.Viral-based modelling and correction of neurodegenerative diseases by RNA interference.Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets?Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cellsABC transporter-driven pharmacoresistance in Amyotrophic Lateral Sclerosis.Selective increase of two ABC drug efflux transporters at the blood-spinal cord barrier suggests induced pharmacoresistance in ALS.Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1(G93A) Mice and Nonhuman Primates.In vivo and in vitro knockdown of FREP2 gene expression in the snail Biomphalaria glabrata using RNA interference.Modulating the expression of disease genes with RNA-based therapy.Allele-specific silencing of the dominant disease allele in sialuria by RNA interference.RNAi: a potential new class of therapeutic for human genetic disease.Silencing human genetic diseases with oligonucleotide-based therapies.High content analysis in amyotrophic lateral sclerosis.Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference.Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model.
P2860
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P2860
RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
RNA interference-mediated sile ...... cultured neuroblastoma cells.
@en
type
label
RNA interference-mediated sile ...... cultured neuroblastoma cells.
@en
prefLabel
RNA interference-mediated sile ...... cultured neuroblastoma cells.
@en
P2093
P2860
P356
P1476
RNA interference-mediated sile ...... cultured neuroblastoma cells.
@en
P2093
Aleksey G Kazantsev
Michele M Maxwell
Piera Pasinelli
P2860
P304
P356
10.1073/PNAS.0308726100
P407
P577
2004-02-23T00:00:00Z