Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine.
about
Cloning and characterization of a family of proteins associated with MplNovel small molecule activators of the Trk family of receptor tyrosine kinasesPeptides identify multiple hotspots within the ligand binding domain of the TNF receptor 2A surrogate-based approach for post-genomic partner identificationRole of romiplostim in splenectomized and nonsplenectomized patients with immune thrombocytopeniaLong-term safety and efficacy of romiplostim for treatment of immune thrombocytopeniaFc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeuticsDrugs derived from phage display: from candidate identification to clinical practiceSmall-molecule inhibitors of protein-protein interactions: progressing towards the dreamSearch and discovery strategies for biotechnology: the paradigm shift.Phage-displayed peptide libraries.A novel peptide, THALWHT, for the targeting of human airway epithelia.Identification of a neuritogenic ligand of the neural cell adhesion molecule using a combinatorial library of synthetic peptides.A rheumatoid factor specific mimotope identified by a peptide display library.Phage-displayed peptides bind to the malarial protein apical membrane antigen-1 and inhibit the merozoite invasion of host erythrocytes.Characterization of a novel NCAM ligand with a stimulatory effect on neurite outgrowth identified by screening a combinatorial peptide library.A potent dimeric peptide antagonist of interleukin-5 that binds two interleukin-5 receptor alpha chainsA peptide mimetic of human interferon (IFN)-beta.Selective recognition of peptide sequences by glutathione transferases: a possible mechanism for modulation of cellular stress-induced signaling pathways.DiSSiMiL: Diverse Small Size Mini-Libraries applied to simple and rapid epitope mapping of a monoclonal antibody.Selection of peptides and synthesis of pentameric peptabody molecules reacting specifically with ErbB-2 receptor.Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7.Phage display of random peptide libraries: applications, limits, and potential.The use of phage display in the study of receptors and their ligands.Combinatorial peptide libraries: mining for cell-binding peptides.The role of the hinge region of the luteinizing hormone receptor in hormone interaction and signal generation.Chemical genetics: ligand-based discovery of gene function.Coiled coil miniprotein randomization on phage leads to charge pattern mimicry of the receptor recognition determinant of interleukin 5.Peptide mimics of the CTLA4-binding domain stimulate T-cell proliferation.A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor.Identification of antiviral mimetic peptides with interferon alpha-2b-like activity from a random peptide library using a novel functional biopanning method.Alternative binding proteins: biological activity and therapeutic potential of cystine-knot miniproteins.Pharmacokinetics, pharmacodynamics, and safety of administering pegylated recombinant megakaryocyte growth and development factor to newborn rhesus monkeys.Thrombopoietin as a drug: biologic expectations, clinical realities, and future directions.A rationally designed agonist antibody fragment that functionally mimics thrombopoietinHaematopoietic stem and progenitor cell-targeted therapies for thrombocytopenia.New insights and therapeutics for immune-mediated thrombocytopenia.A ligand peptide motif selected from a cancer patient is a receptor-interacting site within human interleukin-11.Pharmacodynamics and pharmacokinetics of the novel thrombopoietin mimetic peptide RWJ-800088 in humans.Thrombopoietin and platelet production in chronic immune thrombocytopenia.
P2860
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P2860
Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine.
@en
type
label
Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine.
@en
prefLabel
Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine.
@en
P2093
P1433
P1476
Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine.
@en
P2093
Baccanari DP
Balasubramanian P
Barrett RW
Mattheakis LC
P304
P356
10.1126/SCIENCE.276.5319.1696
P407
P577
1997-06-01T00:00:00Z