The mechanism of Hsp70 chaperones: (entropic) pulling the models together.
about
DEAD-box proteins as RNA helicases and chaperonesEngineering and Evolution of Molecular Chaperones and Protein Disaggregases with Enhanced ActivityMetazoan Hsp70-based protein disaggregases: emergence and mechanismsMediators and mechanisms of heat shock protein 70 based cytoprotection in obstructive nephropathyTargeting heat shock proteins to modulate α-synuclein toxicityWt-1 Expression Linked to Nitric Oxide Availability during Neonatal Obstructive NephropathyHsp70 nucleotide exchange factor Fes1 is essential for ubiquitin-dependent degradation of misfolded cytosolic proteins.Allostery in the Hsp70 chaperone proteinsProteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasisCellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disordersIn vivo generation of neurotoxic prion protein: role for hsp70 in accumulation of misfolded isoformsHsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells.BiP clustering facilitates protein folding in the endoplasmic reticulumHeat shock protein 70 is upregulated in the intestine of intrauterine growth retardation piglets.Molecular chaperones are nanomachines that catalytically unfold misfolded and alternatively folded proteins.The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free systemSingle-molecule spectroscopy reveals chaperone-mediated expansion of substrate protein.Proteomic changes in the rat brain induced by homogenous irradiation and by the bystander effect resulting from high energy synchrotron X-ray microbeams.Quantifying the role of chaperones in protein translocation by computational modeling.Hsp70 clears misfolded kinases that partitioned into distinct quality-control compartments.Multi-layered molecular mechanisms of polypeptide holding, unfolding and disaggregation by HSP70/HSP110 chaperonesQuantitative proteomics of heat-treated human cells show an across-the-board mild depletion of housekeeping proteins to massively accumulate few HSPsMolecular Chaperones of Leishmania: Central Players in Many Stress-Related and -Unrelated Physiological Processes.Mapping the conformation of a client protein through the Hsp70 functional cycle.Cotranslational response to proteotoxic stress by elongation pausing of ribosomes.The Genomes of Three Uneven Siblings: Footprints of the Lifestyles of Three Trichoderma Species.Structural frameworks for considering microbial protein- and nucleic acid-dependent motor ATPases.Clathrin-coat disassembly illuminates the mechanisms of Hsp70 force generationThe E3 ubiquitin ligase UBE3C enhances proteasome processivity by ubiquitinating partially proteolyzed substrates.The role of molecular chaperones in human misfolding diseases.Molecular chaperones as rational drug targets for Parkinson's disease therapeutics.Molecular chaperones and associated cellular clearance mechanisms against toxic protein conformers in Parkinson's disease.Molecular chaperones as enzymes that catalytically unfold misfolded polypeptides.How hsp70 molecular machines interact with their substrates to mediate diverse physiological functions.Structural mechanisms of chaperone mediated protein disaggregation.The role of molecular chaperones in clathrin mediated vesicular trafficking.The redox switch that regulates molecular chaperones.Induction of heat shock proteins in differentiated human neuronal cells following co-application of celastrol and arimoclomol.The remarkable multivalency of the Hsp70 chaperones.Release factor eRF3 mediates premature translation termination on polylysine-stalled ribosomes in Saccharomyces cerevisiae.
P2860
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P2860
The mechanism of Hsp70 chaperones: (entropic) pulling the models together.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The mechanism of Hsp70 chaperones: (entropic) pulling the models together.
@en
type
label
The mechanism of Hsp70 chaperones: (entropic) pulling the models together.
@en
prefLabel
The mechanism of Hsp70 chaperones: (entropic) pulling the models together.
@en
P1476
The mechanism of Hsp70 chaperones: (entropic) pulling the models together.
@en
P2093
Paolo De Los Rios
Pierre Goloubinoff
P304
P356
10.1016/J.TIBS.2007.06.008
P577
2007-07-12T00:00:00Z