Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing.
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Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerPhosphorylation of CLIP-170 by Plk1 and CK2 promotes timely formation of kinetochore-microtubule attachmentsCell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separasePlk1-mediated phosphorylation of Topors regulates p53 stabilityPreclinical Childhood Sarcoma Models: Drug Efficacy Biomarker Identification and ValidationPolo-like kinase 1, on the rise from cell cycle regulation to prostate cancer developmentThe LMO2 oncogene regulates DNA replication in hematopoietic cellsHBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by GemininHBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic developmentJNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stressHistone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancersGCN5 is a positive regulator of origins of DNA replication in Saccharomyces cerevisiae.Polo-box domain: a versatile mediator of polo-like kinase function.Regulatory functional territory of PLK-1 and their substrates beyond mitosis.SCF(FBXW7α) modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stabilityPolo-like kinase 1 activated by the hepatitis B virus X protein attenuates both the DNA damage checkpoint and DNA repair resulting in partial polyploidyInhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease.Plk1 phosphorylation of Orc2 promotes DNA replication under conditions of stressAnalysis of model replication origins in Drosophila reveals new aspects of the chromatin landscape and its relationship to origin activity and the prereplicative complexPolo-like Kinase 1 (Plk1) Up-regulates Telomerase Activity by Affecting Human Telomerase Reverse Transcriptase (hTERT) Stability.Polo-like kinase 1 (Plk1): an Unexpected Player in DNA Replication.DNA sequence templates adjacent nucleosome and ORC sites at gene amplification origins in Drosophila.Mumps Virus Nucleoprotein Enhances Phosphorylation of the Phosphoprotein by Polo-Like Kinase 1.SCF(Fbxw15) mediates histone acetyltransferase binding to origin recognition complex (HBO1) ubiquitin-proteasomal degradation to regulate cell proliferation.FOXM1 participates in PLK1-regulated cell cycle progression in renal cell cancer cells.Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.Plk1 phosphorylation of orc2 and hbo1 contributes to gemcitabine resistance in pancreatic cancer.Hbo1 is a cyclin E/CDK2 substrate that enriches breast cancer stem-like cells.Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation.The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models.The substrates of Plk1, beyond the functions in mitosis.Show me your license, please: deregulation of centriole duplication mechanisms that promote amplification.The role of polo-like kinase 1 in carcinogenesis: cause or consequence?Polo-like kinases: structural variations lead to multiple functions.Understanding the Polo Kinase machine.Lmo2 (LIM-Domain-Only 2) Modulates Sphk1 (Sphingosine Kinase) and Promotes Endothelial Cell Migration.Plk1 inhibition enhances the efficacy of gemcitabine in human pancreatic cancer.Low-dose arsenic-mediated metabolic shift is associated with activation of Polo-like kinase 1 (Plk1).Plk1 Inhibitors in Cancer Therapy: From Laboratory to Clinics.Plk1 inhibition enhances the efficacy of androgen signaling blockade in castration-resistant prostate cancer.
P2860
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P2860
Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing.
@en
type
label
Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing.
@en
prefLabel
Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing.
@en
P2860
P356
P1476
Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing.
@en
P2093
Xiaoqi Liu
Zhao-Qiu Wu
P2860
P304
P356
10.1073/PNAS.0712063105
P407
P577
2008-02-04T00:00:00Z