about
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separasePolo-like kinase 1, on the rise from cell cycle regulation to prostate cancer developmentTimeless links replication termination to mitotic kinase activationElevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway.Pre-RC Protein MCM7 depletion promotes mitotic exit by Inhibiting CDK1 activity.BRCA2 coordinates the activities of cell-cycle kinases to promote genome stabilitySCF(FBXW7α) modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stabilityMinichromosome maintenance helicase activity is controlled by N- and C-terminal motifs and requires the ATPase domain helix-2 insert.Regulation of the final stage of mitosis by components of the pre-replicative complex and a polo kinase.Plk1 phosphorylation of Orc2 promotes DNA replication under conditions of stressProteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate.Polo-like kinase 1 (Plk1): an Unexpected Player in DNA Replication.Plx1 is required for chromosomal DNA replication under stressful conditionsRole for Plk1 phosphorylation of Hbo1 in regulation of replication licensing.Polo-like kinase 1 is essential for early embryonic development and tumor suppression.Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation.Centrosomal protein FOR20 is essential for S-phase progression by recruiting Plk1 to centrosomes.The substrates of Plk1, beyond the functions in mitosis.RNAi-mediated knockdown of MCM7 gene on CML cells and its therapeutic potential for leukemia.Phospho-Bcl-x(L)(Ser62) plays a key role at DNA damage-induced G(2) checkpoint.Polo-like kinase 1 (PLK1)-dependent phosphorylation of methylenetetrahydrofolate reductase (MTHFR) regulates replication via histone methylation.GAK is phosphorylated by c-Src and translocated from the centrosome to chromatin at the end of telophase.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Interaction of chromatin-associated Plk1 and Mcm7
@ast
Interaction of chromatin-associated Plk1 and Mcm7
@en
Interaction of chromatin-associated Plk1 and Mcm7
@en-gb
Interaction of chromatin-associated Plk1 and Mcm7
@nl
type
label
Interaction of chromatin-associated Plk1 and Mcm7
@ast
Interaction of chromatin-associated Plk1 and Mcm7
@en
Interaction of chromatin-associated Plk1 and Mcm7
@en-gb
Interaction of chromatin-associated Plk1 and Mcm7
@nl
prefLabel
Interaction of chromatin-associated Plk1 and Mcm7
@ast
Interaction of chromatin-associated Plk1 and Mcm7
@en
Interaction of chromatin-associated Plk1 and Mcm7
@en-gb
Interaction of chromatin-associated Plk1 and Mcm7
@nl
P356
P1476
Interaction of chromatin-associated Plk1 and Mcm7
@en
P2093
David F Stern
Lyuben Tsvetkov
P304
P356
10.1074/JBC.M413514200
P407
P577
2005-03-25T00:00:00Z