about
An emerging treatment option for glaucoma: Rho kinase inhibitorsRegulation of vascular reactivity in scleroderma: new insights into Raynaud's phenomenonIdentification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damageEarly brain injury, an evolving frontier in subarachnoid hemorrhage researchROCKs as immunomodulators of strokeMetabolic actions of Rho-kinase in periphery and brainThe Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosisPyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2)Pathobiology of wound healing after glaucoma filtration surgeryRho kinase inhibition rescues the endothelial cell cerebral cavernous malformation phenotype.Identification of potential small molecule binding pockets on Rho family GTPasesDistinct signaling mechanisms regulate migration in unconfined versus confined spacesLow intensity pulsed ultrasound (LIPUS) influences the multilineage differentiation of mesenchymal stem and progenitor cell lines through ROCK-Cot/Tpl2-MEK-ERK signaling pathwayChronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA.New approaches to the treatment of pulmonary hypertension: from bench to bedside.Innovative approaches to the therapy of fibrosisCellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.Increased finger skin vasoreactivity and stimulated vasomotion associated with simvastatin therapy in systemic sclerosis hypercholesterolemic patients.Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium.Activation of RhoA-ROCK-BMP signaling reprograms adult human corneal endothelial cells.Maturation and long-term hypoxia-induced acclimatization responses in PKC-mediated signaling pathways in ovine cerebral arterial contractility.RhoA/Rho-kinase and vascular diseases: what is the link?Distinct mesenchymal alterations in N-cadherin and E-cadherin positive primary renal epithelial cellsROCK inhibitor (Y-27632) disrupts somitogenesis in chick embryos.Aberrant ROCK activation promotes the development of type I diabetes in NOD miceRole of the Rho pathway in regulating valvular interstitial cell phenotype and nodule formation.microRNA-124 inhibits migration and invasion by down-regulating ROCK1 in glioma.Transgenic plants as low-cost platform for chemotherapeutic drugs screening"Venopathy" at work: recasting neointimal hyperplasia in a new light.Rho-kinase inhibition attenuates calcium-induced contraction in β-escin but not Triton X-100 permeabilized rabbit femoral arteryRho kinase as a therapeutic target in cardiovascular disease.Staphylococcus aureus protein A mediates invasion across airway epithelial cells through activation of RhoA GTPase signaling and proteolytic activity.RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock.Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation diseaseIncreased leukocyte Rho-associated coiled-coil containing protein kinase activity predicts the presence and severity of coronary vasospastic angina.The selectivity and promiscuity of brain-neuroregenerative inhibitors between ROCK1 and ROCK2 isoforms: An integration of SB-QSSR modelling, QM/MM analysis and in vitro kinase assay.IL-4 Causes Hyperpermeability of Vascular Endothelial Cells through Wnt5A Signaling.Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Rho kinase (ROCK) inhibitors.
@en
type
label
Rho kinase (ROCK) inhibitors.
@en
prefLabel
Rho kinase (ROCK) inhibitors.
@en
P2093
P2860
P1476
Rho kinase (ROCK) inhibitors.
@en
P2093
James K Liao
Kensuke Noma
Minoru Seto
P2860
P356
10.1097/FJC.0B013E318070D1BD
P407
P577
2007-07-01T00:00:00Z