Desensitization of the neurokinin-1 receptor (NK1-R) in neurons: effects of substance P on the distribution of NK1-R, Galphaq/11, G-protein receptor kinase-2/3, and beta-arrestin-1/2 - Wikidata - awgldk - TriplyDB

Desensitization of the neurokinin-1 receptor (NK1-R) in neurons: effects of substance P on the distribution of NK1-R, Galphaq/11, G-protein receptor kinase-2/3, and beta-arrestin-1/2

Desensitization of the neurokinin-1 receptor (NK1-R) in neurons: effects of substance P on the distribution of NK1-R, Galphaq/11, G-protein receptor kinase-2/3, and beta-arrestin-1/2

http://www.wikidata.org/entity/Q36902032

about

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2 Neurokinin-1 receptor desensitization to consecutive microdialysis infusions of substance P in human skin Endothelin-converting enzyme-1 regulates trafficking and signalling of the neurokinin 1 receptor in endosomes of myenteric neurones Endothelin-converting enzyme 1 promotes re-sensitization of neurokinin 1 receptor-dependent neurogenic inflammation G-protein coupled receptor kinases as modulators of G-protein signalling.Heterologous regulation of trafficking and signaling of G protein-coupled receptors: beta-arrestin-dependent interactions between neurokinin receptors.Neutral endopeptidase (EC 3.4.24.11) terminates colitis by degrading substance P Cortical nNOS neurons co-express the NK1 receptor and are depolarized by Substance P in multiple mammalian species.G Protein-Coupled Receptor Trafficking and Signalling in the Enteric Nervous System: The Past, Present and Future.Divergent β-arrestin-dependent signaling events are dependent upon sequences within G-protein-coupled receptor C termini An indirect role for oncomir-519b in the expression of truncated neurokinin-1 in breast cancer cells.The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complex Endosomal endothelin-converting enzyme-1: a regulator of beta-arrestin-dependent ERK signaling.Bradykinin-induced internalization of the human B2 receptor requires phosphorylation of three serine and two threonine residues at its carboxyl tail.Neuropeptide substance P and the immune response.Ubiquitin-dependent down-regulation of the neurokinin-1 receptor.Constitutive ERK1/2 activation by a chimeric neurokinin 1 receptor-beta-arrestin1 fusion protein. Probing the composition and function of the G protein-coupled receptor "signalsome".Recycling and resensitization of the neurokinin 1 receptor. Influence of agonist concentration and Rab GTPases.Clathrin-mediated endocytosis of m3 muscarinic receptors. Roles for Gbetagamma and tubulin.Human substance P receptor lacking the C-terminal domain remains competent to desensitize and internalize.Protein kinase C-mediated desensitization of the neurokinin 1 receptor.Heterologous inhibition of G protein-coupled receptor endocytosis mediated by receptor-specific trafficking of beta-arrestins.Subcellular compartmentalization of activation and desensitization of responses mediated by NK2 neurokinin receptors.Trafficking of proteinase-activated receptor-2 and beta-arrestin-1 tagged with green fluorescent protein. beta-Arrestin-dependent endocytosis of a proteinase receptor.Real-time visualization of the cellular redistribution of G protein-coupled receptor kinase 2 and beta-arrestin 2 during homologous desensitization of the substance P receptor.Thrombin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and -2.Deletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A.The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis.Stimulation of proteinase-activated receptor 2 excites jejunal afferent nerves in anaesthetised rats.Prevention of ginsenoside-induced desensitization of Ca2+-activated Cl- current by microinjection of inositol hexakisphosphate in Xenopus laevis oocytes: involvement of GRK2 and beta-arrestin I.Dynamin and Rab5a-dependent trafficking and signaling of the neurokinin 1 receptor.Activation of neurokinin 3 receptor increases Na(v)1.9 current in enteric neurons.NK-1 receptor desensitization and neutral endopeptidase terminate SP-induced pancreatic plasma extravasation.Involvement of Ca2+ signaling in tachykinin-mediated contractile responses in swine trachea.A Chitosan-Based Liposome Formulation Enhances the In Vitro Wound Healing Efficacy of Substance P Neuropeptide.Development of a BRET2 screening assay using beta-arrestin 2 mutants.Sleep-inducing effect of substance P-cholera toxin A subunit in mice.Ultrastructural localization of beta-arrestin-1 and -2 in rat lumbar spinal cord.Patent highlights August-September 2017.Evidence for a role of caveolin-1 in neurokinin-1 receptor plasma-membrane localization, efficient signaling, and interaction with β-arrestin 2

P2860

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P2860

Desensitization of the neurokinin-1 receptor (NK1-R) in neurons: effects of substance P on the distribution of NK1-R, Galphaq/11, G-protein receptor kinase-2/3, and beta-arrestin-1/2

http://www.wikidata.org/entity/Q36902032

description

1998 nî lūn-bûn

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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1998年论文

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1998年论文

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name

Desensitization of the neuroki ...... ase-2/3, and beta-arrestin-1/2

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type

label

Desensitization of the neuroki ...... ase-2/3, and beta-arrestin-1/2

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Desensitization of the neuroki ...... ase-2/3, and beta-arrestin-1/2

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Desensitization of the neuroki ...... ase-2/3, and beta-arrestin-1/2

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C U Corvera

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P2860

beta-Arrestin: a protein that regulates beta-adrenergic receptor function

Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptor

A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation

Beta-adrenergic receptor kinase: primary structure delineates a multigene family

Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family

Role of phosphorylation in agonist-promoted beta 2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by beta ARK1

Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells

Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family

The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain

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