Developmental regulation of alpha-fetoprotein genes in transgenic mice.
about
An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unitraf regulates the postnatal repression of the mouse alpha-fetoprotein gene at the posttranscriptional levelMouse alpha-fetoprotein gene 5' regulatory elements are required for postnatal regulation by raf and RifThe endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages.Enzymatic engineering of the porcine genome with transposons and recombinases.Transgenic rabbits with lymphocytic leukemia induced by the c-myc oncogene fused with the immunoglobulin heavy chain enhancer.A milk protein gene promoter directs the expression of human tissue plasminogen activator cDNA to the mammary gland in transgenic miceTranscription factor interactions and chromatin modifications associated with p53-mediated, developmental repression of the alpha-fetoprotein gene.Separate cis-regulatory elements confer expression of phosphoenolpyruvate carboxykinase (GTP) gene in different cell linesDevelopmental and transformation-sensitive expression of the Sparc gene on mouse chromosome 11Regulated expression of the Ren-2 gene in transgenic mice derived from parental strains carrying only the Ren-1 geneExpression of the murine apolipoprotein E gene is coupled to the differentiated state of F9 embryonal carcinoma cells.Specific sets of DNase I-hypersensitive sites are associated with the potential and overt expression of the rat albumin and alpha-fetoprotein genes.An enhancer responsible for activating transcription at the midblastula transition in Xenopus developmentTissue-specific expression of the human type II collagen gene in mice.Methylation of the alphafetoprotein gene in cell populations isolated from rat livers during carcinogenesis.Developmental and tissue-specific expression directed by the alpha 2 type I collagen promoter in transgenic mice.Tg(Afp-GFP) expression marks primitive and definitive endoderm lineages during mouse development.Multiple positive and negative elements regulate human brain creatine kinase gene expressionDifferential requirements for cellular enhancers in stem and differentiated cells.Tissue-specific expression of the rat beta-casein gene in transgenic mice.Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice.alpha-Fetoprotein gene sequences mediating Afr2 regulation during liver regeneration.Rat glycine methyltransferase. Complete amino acid sequence deduced from a cDNA clone and characterization of the genomic DNA.c-Ha-ras down regulates the alpha-fetoprotein gene but not the albumin gene in human hepatoma cells.Tissue-specific and insulin-dependent expression of a pancreatic amylase gene in transgenic mice.Albumin and alpha-fetoprotein gene transcription in rat hepatoma cell lines is correlated with specific DNA hypomethylation and altered chromatin structure in the 5' region.A Mup promoter-thymidine kinase reporter gene shows relaxed tissue-specific expression and confers male sterility upon transgenic mice.Interaction of a hepatoma-specific nuclear factor with transcription-regulatory sequences of the human alpha-fetoprotein and albumin genes.Multiple regulatory elements in the intergenic region between the alpha-fetoprotein and albumin genesEstrogen regulation of the avian transferrin gene in transgenic mice.A foreign dihydrofolate reductase gene in transgenic mice acts as a dominant mutationTissue-specific and developmentally regulated expression of a chimeric actin-globin gene in transgenic mice.The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice.Promoter and enhancer elements from the rat elastase I gene function independently of each other and of heterologous enhancersProviral sequences that restrict retroviral expression in mouse embryonal carcinoma cellsIntroduction of genes into the germ line of animals.Leukemia inhibitory factor is expressed by the preimplantation uterus and selectively blocks primitive ectoderm formation in vitroTransgenic regulation in laboratory animals.Cell type-specific negative regulatory element in the control region of the rat alpha-fetoprotein gene.
P2860
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P2860
Developmental regulation of alpha-fetoprotein genes in transgenic mice.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
1985年论文
@zh
1985年论文
@zh-cn
name
Developmental regulation of alpha-fetoprotein genes in transgenic mice.
@en
type
label
Developmental regulation of alpha-fetoprotein genes in transgenic mice.
@en
prefLabel
Developmental regulation of alpha-fetoprotein genes in transgenic mice.
@en
P2093
P2860
P356
P1476
Developmental regulation of alpha-fetoprotein genes in transgenic mice.
@en
P2093
R E Hammer
R Krumlauf
R L Brinster
S M Tilghman
P2860
P304
P356
10.1128/MCB.5.7.1639
P407
P577
1985-07-01T00:00:00Z