about
Possible role of ABO system in age-related diseases and longevity: a narrative reviewDeficiency in Poly(ADP-ribose) Polymerase-1 (PARP-1) Accelerates Aging and Spontaneous Carcinogenesis in MiceEpigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in healthLithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cellsModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesThe H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescenceA selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiencyLinking functional decline of telomeres, mitochondria and stem cells during ageingChallenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?Aging-Induced Stem Cell Mutations as Drivers for Disease and CancerIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesS6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage responseBioactive Nutrients and Nutrigenomics in Age-Related Diseases.The yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence.Centrosome misorientation reduces stem cell division during ageing.Lymphotoxin-alpha polymorphisms and presence of cancer in 1,536 consecutive autopsy casesIt's all about balance: p53 and agingTissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.Senescent cells: a novel therapeutic target for aging and age-related diseasesGene expression changes with age in skin, adipose tissue, blood and brain.p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo.Bladder cancer in the elderly: clinical outcomes, basic mechanisms, and future research direction.Removing all obstacles: a critical role for p53 in promoting tissue renewalMechanisms underlying the anti-aging and anti-tumor effects of lithocholic bile acidCirculating MicroRNAs as easy-to-measure aging biomarkers in older breast cancer patients: correlation with chronological age but not with fitness/frailty status.Telomeres in cancer and ageing.Reconvene and reconnect the antioxidant hypothesis in human health and disease.Polμ deficiency increases resistance to oxidative damage and delays liver aging.Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection?53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.Age-related increase in IL-17 activates pro-inflammatory signaling in prostate cells.Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy.E2F1 and p53 transcription factors as accessory factors for nucleotide excision repair.Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations.How does suppression of IGF-1 signaling by DNA damage affect aging and longevity?Aging by epigenetics--a consequence of chromatin damage?Immunity, ageing and cancer.Signal transduction of fertilization in frog eggs and anti-apoptotic mechanism in human cancer cells: common and specific functions of membrane microdomains.Mitochondria-mediated energy adaption in cancer: the H(+)-ATP synthase-geared switch of metabolism in human tumors.Impact of aging on the biology of breast cancer.
P2860
Q21093222-A19FFE8F-0653-4DCF-BF1D-D198E4AC2944Q21342802-6A0193E4-366C-4462-85C3-729F095626FCQ24604190-B20E44D6-CDFE-4833-A8AE-F2E5A127AC3FQ24617423-6BBE15AD-AC02-4A4B-BEC1-974ABC4D2DE2Q24644033-69B1E2A4-056F-4C8B-95D1-AFC47D598DF4Q28245403-9D55320D-DCEF-4206-AD9E-41AB3E37C69EQ28256846-B64B8A11-DFD0-421B-BF1C-5F49A93B106AQ28277689-536852DE-1C78-4785-BDAB-67EE9CDB8EBEQ28383732-CE8A3B6D-9C8D-41E0-8EA5-2C00D179E56CQ28384025-13A10CB4-948A-44DD-BD82-854421D23D06Q28388335-6C994C9B-C832-455A-831D-7A11C3767C1CQ28509658-4C04132A-958D-4CAB-B26B-892370D232E7Q30239072-A8B64D57-8274-4D80-8F88-15976DD97D00Q30426400-803DE791-DBA1-4FF8-87C6-A5E41DABC030Q30488902-83647EF3-C889-46A2-A016-3E5FC4B855EBQ33359870-1069432F-ED37-43B1-ACA7-7E224EDECBD4Q33627910-897AFAED-2456-4CCE-9E07-48674474FD0DQ33661151-0E45B4F6-F68A-4899-81C4-D635A6573729Q33732761-89DEDB33-F384-4C76-A7D2-59F081578DDCQ33742819-4EA28E1E-377D-4231-8797-8D01750A68C6Q33809750-7684FFA9-6E65-4C07-9F9E-859786FBD17FQ34215285-1395B18E-3488-4ADA-8E1D-AD32F0DE3CC4Q34306322-E58CAFC7-BEA4-4B8F-BB25-11F0ADF75CC2Q34358930-740CBF7B-116F-43BF-A074-7D1211832C84Q34380210-12B33CA4-6AC3-48D6-9CF9-886054C34B3EQ34402746-EF6F50E2-3881-4A3E-96B4-EF2E438CB152Q34405837-6F611CB8-2914-4FEF-99E0-7CBF707CB8E6Q35137565-BF3D6D72-9355-4938-9190-12A15C942B4FQ35188247-876E09B9-2DA8-43C8-B736-F77CC98801CEQ35283684-57F026F2-D065-40B0-A40D-9C029030E533Q35538312-17581B69-BDD6-4A14-80B0-092DD07DFC23Q36288310-9E28CC67-EF07-438D-91B3-8417E708921EQ36396607-088BB96D-39B5-4B29-8072-6B21A7D6C9A3Q36446664-8E4A0FE2-EAC2-47CE-A587-748DEE484EC4Q36676675-16609910-09BD-4496-819D-C69464EDAB45Q36766079-D9E02F2F-5723-479C-AD5D-B71978A56BEDQ36930979-7D701ABA-9D6D-4E79-8B56-8162D4AC6E08Q36944110-8B348B62-9655-4877-910D-510AC37F521AQ36953477-E40252E6-21E6-4D4F-B872-42112F2B7C4CQ36976234-D2750A7D-A158-485D-B506-91E4DAEAFCE8
P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Cancer and ageing: convergent and divergent mechanisms.
@en
type
label
Cancer and ageing: convergent and divergent mechanisms.
@en
prefLabel
Cancer and ageing: convergent and divergent mechanisms.
@en
P356
P1476
Cancer and ageing: convergent and divergent mechanisms.
@en
P2888
P304
P356
10.1038/NRM2242
P577
2007-09-01T00:00:00Z
P5875
P6179
1033612140