The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization
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1.92 Angstrom Zinc-Free APOBEC3F Catalytic Domain Crystal StructureCytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization.Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity.Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulationNatural Polymorphisms and Oligomerization of Human APOBEC3H Contribute to Single-stranded DNA Scanning Ability.Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.Functional requirements of AID's higher order structures and their interaction with RNA-binding proteinsStructural analysis of the activation-induced deoxycytidine deaminase required in immunoglobulin diversificationNuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity.Crystal structures of APOBEC3G N-domain alone and its complex with DNA.Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.A Novel Regulator of Activation-Induced Cytidine Deaminase/APOBECs in Immunity and Cancer: Schrödinger's CATalytic Pocket.Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancer.Structural and functional assessment of APOBEC3G macromolecular complexes.The APOBEC Protein Family: United by Structure, Divergent in Function.Functions and Malfunctions of Mammalian DNA-Cytosine DeaminasesRNA binding to APOBEC deaminases; Not simply a substrate for C to U editing.Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression.Zinc enhancement of cytidine deaminase activity highlights a potential allosteric role of loop-3 in regulating APOBEC3 enzymes.Conservation and Innovation of APOBEC3A Restriction Functions during Primate Evolution.Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA.Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B.Human Papillomavirus 16 E7 Stabilizes APOBEC3A Protein by Inhibiting Cullin 2-dependent Protein Degradation.Mechanisms for targeted, purposeful mutation revealed in an APOBEC-DNA complex.Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H.Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment.A fluorescent reporter for quantification and enrichment of DNA editing by APOBEC-Cas9 or cleavage by Cas9 in living cells.Crystal structure of the catalytic domain of HIV-1 restriction factor APOBEC3G in complex with ssDNA.Substrate sequence selectivity of APOBEC3A implicates intra-DNA interactions.The rabbit as an orthologous small animal model for APOBEC3A oncogenesis.Modeling the Embrace of a Mutator: APOBEC Selection of Nucleic Acid Ligands
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P2860
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization
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2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization
@en
type
label
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization
@en
prefLabel
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization
@en
P2093
P2860
P1433
P1476
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization
@en
P2093
Brian A Kelch
Celia A Schiffer
Ellen A Nalivaika
Mohan Somasundaran
Nese Kurt-Yilmaz
Sean P Ryder
Shivender M D Shandilya
Takahide Kouno
Tania V Silvas
P2860
P304
P356
10.1016/J.STR.2015.03.016
P577
2015-04-23T00:00:00Z