BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact. - Wikidata - awgldk - TriplyDB

BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact.

BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact.

http://www.wikidata.org/entity/Q36926846

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Targeted approaches to induce immune tolerance for Pompe disease therapy B cells with regulatory properties in transplantation tolerance Resolve, revise, and relax: the 3 Rs of B cell repertoire adjustment CD73 expression is dynamically regulated in the germinal center and bone marrow plasma cells are diminished in its absence Protective antiviral antibody responses in a mouse model of influenza virus infection require TACI BAFF mediates splenic B cell response and antibody production in experimental Chagas disease.VNAR single-domain antibodies specific for BAFF inhibit B cell development by molecular mimicry B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction.APRIL mediates peritoneal B-1 cell homeostasis.B cells and humoral immunity in atherosclerosis Effect of long-term belimumab treatment on B cells in systemic lupus erythematosus: extension of a phase II, double-blind, placebo-controlled, dose-ranging study.Lupus nephritis: lessons from murine models B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals.Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.B-lymphocyte homeostasis and BLyS-directed immunotherapy in transplantation.Germinal center selection and the development of memory B and plasma cells.A role for IL-27p28 as an antagonist of gp130-mediated signaling.B-1a lymphocytes attenuate insulin resistance B cell activating factor (BAFF) and a proliferation inducing ligand (APRIL) mediate CD40-independent help by memory CD4 T cells.Cellular competition independent of BAFF/B lymphocyte stimulator results in low frequency of an autoreactive clonotype in mature polyclonal B cell compartments Cutting edge: Hierarchy of maturity of murine memory B cell subsets.Immunoglobulin secretion by B1 cells: differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells.A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice Universal expression and dual function of the atypical chemokine receptor D6 on innate-like B cells in mice.Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease B lymphocyte stimulator levels in systemic lupus erythematosus: higher circulating levels in African American patients and increased production after influenza vaccination in patients with low baseline levels.BAFF blockade prevents anti-drug antibody formation in a mouse model of Pompe disease Adaptive Immunity and Antigen-Specific Activation in Obesity-Associated Insulin Resistance.Dispensability of APRIL to the development of systemic lupus erythematosus in NZM 2328 mice.Meningeal Infiltration of the Spinal Cord by Non-Classically Activated B Cells is Associated with Chronic Disease Course in a Spontaneous B Cell-Dependent Model of CNS Autoimmune Disease Rational clinical trial design for antibody mediated renal allograft injury.Chronic inflammation and aging: DNA damage tips the balance.Cellular Dynamics of Memory B Cell Populations: IgM+ and IgG+ Memory B Cells Persist Indefinitely as Quiescent Cells.Inhibition of B cell activating factor (BAFF) in the management of systemic lupus erythematosus (SLE).B-cell activating factor targeted therapy and lupus.Development of systemic lupus erythematosus in NZM 2328 mice in the absence of any single BAFF receptor.HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life.BAFF- and APRIL-dependent maintenance of antibody titers after immunization with T-dependent antigen and CD1d-binding ligand.The role of B lymphocyte stimulator (BLyS) in systemic lupus erythematosus.B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans.

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P2860

BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact.

http://www.wikidata.org/entity/Q36926846

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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BLyS inhibition eliminates pri ...... uired humoral immunity intact.

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BLyS inhibition eliminates pri ...... uired humoral immunity intact.

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PNAS.0807841105

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

BLyS inhibition eliminates pri ...... uired humoral immunity intact.

@en

P2093

Chris Ward

http://www.w3.org/2001/XMLSchema#string

Jean L Scholz

http://www.w3.org/2001/XMLSchema#string

Jenni E Crowley

http://www.w3.org/2001/XMLSchema#string

Juli P Miller

http://www.w3.org/2001/XMLSchema#string

Mark J Shlomchik

http://www.w3.org/2001/XMLSchema#string

Mary M Tomayko

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Michael P Cancro

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Natalie Steinel

http://www.w3.org/2001/XMLSchema#string

Patrick J O'Neill

http://www.w3.org/2001/XMLSchema#string

Radhika Goenka

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P2860

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency

Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells

BCMA is essential for the survival of long-lived bone marrow plasma cells

Cellular origin of human B-cell lymphomas.

B cell development in mice that lack one or both immunoglobulin kappa light chain genes.

Naive and memory B cells in T-cell-dependent and T-independent responses.

Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities

Autoreactivity in human IgG+ memory B cells.

The biochemistry and biology of BAFF, APRIL and their receptors.

P304

15517-15522

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scholarly article

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10.1073/PNAS.0807841105

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P407

P433

40

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P478

105

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P577

2008-10-01T00:00:00Z

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235614284

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18832171

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2563088

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