Human sperm devoid of PLC, zeta 1 fail to induce Ca(2+) release and are unable to initiate the first step of embryo development
about
Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation.A recurrent deletion of DPY19L2 causes infertility in man by blocking sperm head elongation and acrosome formationPhosphoinositides: tiny lipids with giant impact on cell regulationPLCζ or PAWP: revisiting the putative mammalian sperm factor that triggers egg activation and embryogenesisUnderstanding fertilization through intracytoplasmic sperm injection (ICSI)Involvement of opsins in mammalian sperm thermotaxisHomozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWPNovel regulation of PLCζ activity via its XY-linkerOocyte activation, phospholipase C zeta and human infertility.Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca(2+) oscillations required for mammalian oocyte activation"This is where it all started" - the pivotal role of PLCζ within the sophisticated process of mammalian reproduction: a systemic review.Protein phospholipase C Zeta1 expression in patients with failed ICSI but with normal sperm parametersPortrait of an oocyte: our obscure origin.Complete globozoospermia associated with PLCζ deficiency treated with calcium ionophore and ICSI results in pregnancyInositol 1,4,5-trisphosphate receptor 1 degradation in mouse eggs and impact on [Ca2+]i oscillationsThe testicular and epididymal expression profile of PLCζ in mouse and human does not support its role as a sperm-borne oocyte activating factor.Role of gonadotropin regulated testicular RNA helicase (GRTH/Ddx25) on polysomal associated mRNAs in mouse testis.Sperm-specific post-acrosomal WW-domain binding protein (PAWP) does not cause Ca2+ release in mouse oocytes.A novel culture system for mouse spermatid maturation which produces elongating spermatids capable of inducing calcium oscillation during fertilization and embryonic development.Paternal RNA contributions in the Caenorhabditis elegans zygote.PLCz functional haplotypes modulating promoter transcriptional activity are associated with semen quality traits in Chinese Holstein bulls.Ca2+ signaling during mammalian fertilization: requirements, players, and adaptations.Mutations of the aurora kinase C gene causing macrozoospermia are the most frequent genetic cause of male infertility in Algerian men.Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation.Phospholipase Cζ binding to PtdIns(4,5)P2 requires the XY-linker regionComparative testicular transcriptome of wild type and globozoospermic Dpy19l2 knock out miceMale infertility-linked point mutation disrupts the Ca2+ oscillation-inducing and PIP(2) hydrolysis activity of sperm PLCζ.Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes.Is PAWP the "real" sperm factor?Re: Is PAWP the 'real' sperm factor?A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertilityHealthy twin live-birth after ionophore treatment in a case of theophylline-resistant Kartagener syndromePLCζ disruption with complete fertilization failure in normozoospermia.Oocyte activation and phospholipase C zeta (PLCζ): diagnostic and therapeutic implications for assisted reproductive technology.Rescue of failed oocyte activation after ICSI in a mouse model of male factor infertility by recombinant phospholipase CζPhospholipase C-zeta deficiency as a cause for repetitive oocyte fertilization failure during ovarian stimulation for in vitro fertilization with ICSI: a case reportComplementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction.Sperm Oxidative Stress Is Detrimental to Embryo Development: A Dose-Dependent Study Model and a New and More Sensitive Oxidative Status Evaluation.Signal transduction in mammalian oocytes during fertilization.Essential Role of the EF-hand Domain in Targeting Sperm Phospholipase Cζ to Membrane Phosphatidylinositol 4,5-Bisphosphate (PIP2).
P2860
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P2860
Human sperm devoid of PLC, zeta 1 fail to induce Ca(2+) release and are unable to initiate the first step of embryo development
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Human sperm devoid of PLC, zet ...... rst step of embryo development
@en
type
label
Human sperm devoid of PLC, zet ...... rst step of embryo development
@en
prefLabel
Human sperm devoid of PLC, zet ...... rst step of embryo development
@en
P2093
P2860
P356
P1476
Human sperm devoid of PLC, zet ...... rst step of embryo development
@en
P2093
Ana Maria Salicioni
Daniel Grow
Hoi Chang Lee
Jesse Mager
John Parrington
Jose B Cibelli
Kevin Coward
Myung-Sik Yoo
Pablo E Visconti
Rafael A Fissore
P2860
P304
P356
10.1172/JCI36942
P407
P577
2008-10-16T00:00:00Z