Lessons from the first comprehensive molecular characterization of cell cycle control in rodent insulinoma cell lines
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Development, growth and maintenance of β-cell mass: models are also part of the storyEpoxypukalide induces proliferation and protects against cytokine-mediated apoptosis in primary cultures of pancreatic β-cellsmRNA expression analysis of cell cycle genes in islets of pregnant miceIslet biology, the CDKN2A/B locus and type 2 diabetes risk.Cytoplasmic-nuclear trafficking of G1/S cell cycle molecules and adult human β-cell replication: a revised model of human β-cell G1/S controlActivated FoxM1 attenuates streptozotocin-mediated β-cell death.Inhibition of fatty acid metabolism reduces human myeloma cells proliferation.Cyclin C stimulates β-cell proliferation in rat and human pancreatic β-cellsInhibition of Id1 augments insulin secretion and protects against high-fat diet-induced glucose intolerance.cMyc is a principal upstream driver of beta-cell proliferation in rat insulinoma cell lines and is an effective mediator of human beta-cell replication.ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.Human β-cell proliferation and intracellular signaling: driving in the dark without a road map.Overexpression of hepatocyte nuclear factor-4α initiates cell cycle entry, but is not sufficient to promote β-cell expansion in human isletsA high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.High-throughput Functional Genomics Identifies Regulators of Primary Human Beta Cell Proliferation.Enhanced beta cell proliferation in mice overexpressing a constitutively active form of Akt and one allele of p21Cip.TGF-β Signaling Regulates Pancreatic β-Cell Proliferation through Control of Cell Cycle Regulator p27 Expression.Early and Late G1/S Cyclins and Cdks Act Complementarily to Enhance Authentic Human β-Cell Proliferation and Expansion.Insulin receptor-overexpressing β-cells ameliorate hyperglycemia in diabetic rats through Wnt signaling activationAssembly, activation, and substrate specificity of cyclin D1/Cdk2 complexes.The retinoblastoma protein and its homolog p130 regulate the G1/S transition in pancreatic beta-cells.Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin ReceptorNutrition-/diet-induced changes in gene expression in pancreatic β-cells.Diabetes mellitus--advances and challenges in human β-cell proliferation.Cell cycle-related metabolism and mitochondrial dynamics in a replication-competent pancreatic beta-cell line.A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform.Generation of Insulin-Producing Cells From Human-Induced Pluripotent Stem Cells Using a Stepwise Differentiation Protocol Optimized With Platelet-Rich Plasma.Crosstalk Between Activated Myofibroblasts and β Cells in Injured Mouse Pancreas.Selective inhibition of 12-lipoxygenase protects islets and beta cells from inflammatory cytokine-mediated beta cell dysfunction.Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia.Mechanisms of action of islet neogenesis-associated protein: comparison of the full-length recombinant protein and a bioactive peptide.Betacellulin ameliorates hyperglycemia in obese diabetic db/db mice.Overexpression of E2F3 promotes proliferation of functional human β cells without induction of apoptosis.Dynamics of glucose and insulin concentration connected to the β-cell cycle: model development and analysis.Agaricus bisporus lectins mediates islet β-cell proliferation through regulation of cell cycle proteins.Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation.
P2860
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P2860
Lessons from the first comprehensive molecular characterization of cell cycle control in rodent insulinoma cell lines
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Lessons from the first compreh ...... n rodent insulinoma cell lines
@en
type
label
Lessons from the first compreh ...... n rodent insulinoma cell lines
@en
prefLabel
Lessons from the first compreh ...... n rodent insulinoma cell lines
@en
P2093
P2860
P356
P1433
P1476
Lessons from the first compreh ...... n rodent insulinoma cell lines
@en
P2093
Andrew F Stewart
Brian Sicari
Donald K Scott
George Harb
Karen Selk
Karen Takane
Nathalie Fiaschi-Taesch
Pili Zhang
Rupangi Vasavada
P2860
P304
P356
10.2337/DB08-0393
P407
P577
2008-07-23T00:00:00Z