Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products
about
The G11 gene located in the major histocompatibility complex encodes a novel nuclear serine/threonine protein kinaseThe complete coding sequence of arg defines the Abelson subfamily of cytoplasmic tyrosine kinasesNuclear and cytoplasmic location of the FER tyrosine kinaseProfiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.Characterization of a novel member of the DOK family that binds and modulates Abl signalingActivation of murine c-abl protooncogene: effect of a point mutation on oncogenic activationMechanism of activation of the human trk oncogeneThe PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activityProduction of high-titer helper-free retroviruses by transient transfectionEvidence for regulation of the human ABL tyrosine kinase by a cellular inhibitorBCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.Molecular mechanisms of cancer.Subcellular distribution of p210(BCR-ABL) in CML cell lines and primary CD34+ CML cells.Deletion of an N-terminal regulatory domain of the c-abl tyrosine kinase activates its oncogenic potentialN-terminal mutations activate the leukemogenic potential of the myristoylated form of c-ablFrequent generation of oncogenes by in vitro recombination of TRK protooncogene sequences.Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein.Signaling by ABL oncogenes through cyclin D1.Localization of preferential sites of rearrangement within the BCR gene in Philadelphia chromosome-positive acute lymphoblastic leukemiaThe ltk receptor tyrosine kinase is expressed in pre-B lymphocytes and cerebral neurons and uses a non-AUG translational initiatorStimulation of p53 DNA binding by c-Abl requires the p53 C terminus and tetramerization.Identification and biochemical characterization of p70TRK, product of the human TRK oncogene.Cell lines and peripheral blood leukocytes derived from individuals with chronic myelogenous leukemia display virtually identical proteins phosphorylated on tyrosine residuesAptameric inhibition of p210bcr-abl tyrosine kinase autophosphorylation by oligodeoxynucleotides of defined sequence and backbone structureThe biology of chronic myelogenous leukemia:mouse models and cell adhesion.Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies.Chronic myeloid leukemia: pathophysiology, diagnostic parameters, and current treatment concepts.Variable expression of the translocated c-abl oncogene in Philadelphia-chromosome-positive B-lymphoid cell lines from chronic myelogenous leukemia patientsExpression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias.PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia.Diverging fates of cells of origin in acute and chronic leukaemia.Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl.Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia.SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence.Tyrosine kinase inhibitor AG1024 exerts antileukaemic effects on STI571-resistant Bcr-Abl expressing cells and decreases AKT phosphorylation.Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells.Temperature-sensitive mutants of Abelson murine leukemia virus deficient in protein tyrosine kinase activity.The 5' noncoding region of the human leukemia-associated oncogene BCR/ABL is a potent inhibitor of in vitro translation.Monoclonal antibodies specific for v-abl- and c-abl-encoded molecules.Molecular analysis of the Philadelphia chromosome.
P2860
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P2860
Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
1985年论文
@zh
1985年论文
@zh-cn
name
Detection of c-abl tyrosine ki ...... and altered abl gene products
@en
type
label
Detection of c-abl tyrosine ki ...... and altered abl gene products
@en
prefLabel
Detection of c-abl tyrosine ki ...... and altered abl gene products
@en
P2860
P356
P1476
Detection of c-abl tyrosine ki ...... and altered abl gene products
@en
P2093
J B Konopka
P2860
P304
P356
10.1128/MCB.5.11.3116
P407
P577
1985-11-01T00:00:00Z