Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion. - Wikidata - awgldk - TriplyDB

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.

http://www.wikidata.org/entity/Q36954381

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Identification of a polymorphism in the RING finger of human Bmi-1 that causes its degradation by the ubiquitin-proteasome system Adult lung stem cells and their contribution to lung tumourigenesis Epigenetics of lung cancer Polycomb group protein Bmi1 is required for growth of RAF driven non-small-cell lung cancer Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis Ubiquitination and degradation of ribonucleotide reductase M1 by the polycomb group proteins RNF2 and Bmi1 and cellular response to gemcitabine Commentary: Sca-1 and Cells of the Lung: A matter of Different Sorts CTIP2 expression in human head and neck squamous cell carcinoma is linked to poorly differentiated tumor status.Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression.CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells Tissue-specific p19Arf regulation dictates the response to oncogenic K-ras.c-Myc regulates self-renewal in bronchoalveolar stem cells.Methylation and silencing of miRNA-124 by EVI1 and self-renewal exhaustion of hematopoietic stem cells in murine myelodysplastic syndrome.Matrix metalloproteinase-10 promotes Kras-mediated bronchio-alveolar stem cell expansion and lung cancer formation Lung cancer: developmental networks gone awry?Primitive origins of prostate cancer: in vivo evidence for prostate-regenerating cells and prostate cancer-initiating cells The side population in human lung cancer cell line NCI-H460 is enriched in stem-like cancer cells.Bmi1 is required for hepatic progenitor cell expansion and liver tumor development.Polycomb genes expression as a predictor of poor clinical outcome in children with medulloblastoma.Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.Validation of Bmi1 as a therapeutic target of hepatocellular carcinoma in mice.Chromatin regulatory mechanisms in pluripotency.Lung progenitors from lambs can differentiate into specialized alveolar or bronchiolar epithelial cells.Isolation of alveolar epithelial type II progenitor cells from adult human lungs.The microRNA miR-34a inhibits non-small cell lung cancer (NSCLC) growth and the CD44hi stem-like NSCLC cells Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci.Nuclear-encoded cytochrome c oxidase subunit 4 regulates BMI1 expression and determines proliferative capacity of high-grade gliomas The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development Tumor oncogenotypes and lung cancer stem cell identity.Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.Bmi-1: At the crossroads of physiological and pathological biology.Cardiac Bmi1(+) cells contribute to myocardial renewal in the murine adult heart Bmi1 is required for regeneration of the exocrine pancreas in mice BMI1, ALDH1A1, and CD133 Transcripts Connect Epithelial-Mesenchymal Transition to Cancer Stem Cells in Lung Carcinoma BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance KLF4 regulates adult lung tumor-initiating cells and represses K-Ras-mediated lung cancer.Epigenetics of pluripotent cells.Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis Cancer vaccines: Looking to the future.Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment.

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P2860

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.

http://www.wikidata.org/entity/Q36954381

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.

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type

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Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.

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prefLabel

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.

@en

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Carla F Kim

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Jacqueline A Lees

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Jennifer Shepard Dovey

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Sima J Zacharek

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P2860

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways.

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

Cancer statistics, 2007

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

Identification of bronchioalveolar stem cells in normal lung and lung cancer

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

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105

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