Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration.
about
Molecular mechanisms of biological aging in intervertebral discsGlucocorticoids induce senescence in primary human tenocytes by inhibition of sirtuin 1 and activation of the p53/p21 pathway: in vivo and in vitro evidence.In vivo experimental intervertebral disc degeneration induced by bleomycin in the rhesus monkeyConstitutive expression of cathepsin K in the human intervertebral disc: new insight into disc extracellular matrix remodeling via cathepsin K and receptor activator of nuclear factor-κB ligand.Caveolin-1, cellular senescence and age-related diseases.Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus FibrosusIncreased caveolin-1 in intervertebral disc degeneration facilitates repairLeptin changes differentiation fate and induces senescence in chondrogenic progenitor cellsGene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies.Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways.An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue.High Glucose-Induced Oxidative Stress Mediates Apoptosis and Extracellular Matrix Metabolic Imbalances Possibly via p38 MAPK Activation in Rat Nucleus Pulposus Cells.Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytesMMTV promoter-regulated caveolin-1 overexpression yields defective parenchymal epithelia in multiple exocrine organs of transgenic mice.17beta-estradiol Attenuates TNF-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway.Understanding the native nucleus pulposus cell phenotype has important implications for intervertebral disc regeneration strategies.Development of an intact intervertebral disc organ culture system in which degeneration can be induced as a prelude to studying repair potential.Comparison of Oxygen Consumption Rates of Nondegenerate and Degenerate Human IVD Cells.A role for TNFα in intervertebral disc degeneration: a non-recoverable catabolic shift.High-magnitude compression accelerates the premature senescence of nucleus pulposus cells via the p38 MAPK-ROS pathway.Potential of co-culture of nucleus pulposus mesenchymal stem cells and nucleus pulposus cells in hyperosmotic microenvironment for intervertebral disc regeneration.Caveolin‑1 regulates oxidative stress‑induced senescence in nucleus pulposus cells primarily via the p53/p21 signaling pathway in vitro.Inflammatory cytokines induce caveolin-1/β-catenin signalling in rat nucleus pulposus cell apoptosis through the p38 MAPK pathway.Activation of the cannabinoid receptor 1 by ACEA suppresses senescence in human primary chondrocytes through sirt1 activation.Apoptosis, senescence, and autophagy in rat nucleus pulposus cells: Implications for diabetic intervertebral disc degeneration.Isolation and identification of stem cells from degenerated human intervertebral discs and their migration characteristics.Safety of intradiscal injection and biocompatibility of polyester amide microspheres in a canine model predisposed to intervertebral disc degeneration.
P2860
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P2860
Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Caveolin-1 expression and stre ...... ervertebral disc degeneration.
@en
type
label
Caveolin-1 expression and stre ...... ervertebral disc degeneration.
@en
prefLabel
Caveolin-1 expression and stre ...... ervertebral disc degeneration.
@en
P2860
P356
P1476
Caveolin-1 expression and stre ...... tervertebral disc degeneration
@en
P2093
Judith Alison Hoyland
Sarah Kathleen Heathfield
P2860
P2888
P356
10.1186/AR2468
P577
2008-08-05T00:00:00Z
P5875
P6179
1009197026