Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs. - Wikidata - awgldk - TriplyDB

Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs.

Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs.

http://www.wikidata.org/entity/Q36969808

about

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data Antibiotics in malaria therapy: which antibiotics except tetracyclines and macrolides may be used against malaria?New developments in anti-malarial target candidate and product profiles A New Set of Chemical Starting Points with Plasmodium falciparum Transmission-Blocking Potential for Antimalarial Drug Discovery Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum.An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmission Perforin-like protein PPLP2 permeabilizes the red blood cell membrane during egress of Plasmodium falciparum gametocytes A novel multiple-stage antimalarial agent that inhibits protein synthesis Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen Developing transmission-blocking strategies for malaria control.Evaluation of Plasmodium falciparum gametocyte detection in different patient material.A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs Effect of fluorescent dyes on in vitro-differentiated, late-stage Plasmodium falciparum gametocytes.Lead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations.Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria Antimalarial iron chelator FBS0701 blocks transmission by Plasmodium falciparum gametocyte activation inhibition.Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans Synthesis and evaluation of the antiplasmodial activity of tryptanthrin derivatives.Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation.Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination.Potent Ex Vivo Activity of Naphthoquine and Methylene Blue against Drug-Resistant Clinical Isolates of Plasmodium falciparum and Plasmodium vivax.Plasmodium transmission blocking activities of Vernonia amygdalina extracts and isolated compounds.Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds Gametocyte Clearance Kinetics Determined by Quantitative Magnetic Fractionation in Melanesian Children with Uncomplicated Malaria Treated with Artemisinin Combination Therapy.A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes.Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum Gametocytes.Single low dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission after artemether-lumefantrine in children with asymptomatic infection: a randomised, double-blind, placebo-controlled trial.Inclusion of gametocyte parameters in anti-malarial drug efficacy studies: filling a neglected gap needed for malaria elimination In Vitro Activities of Primaquine-Schizonticide Combinations on Asexual Blood Stages and Gametocytes of Plasmodium falciparum The Nonartemisinin Sesquiterpene Lactones Parthenin and Parthenolide Block Plasmodium falciparum Sexual Stage Transmission.Transmission-Blocking Potential of MEFAS, a Hybrid Compound Derived from Artesunate and Mefloquine Piperaquine Monotherapy of Drug-Susceptible Plasmodium falciparum Infection Results in Rapid Clearance of Parasitemia but Is Followed by the Appearance of Gametocytemia.A novel validated assay to support the discovery of new anti-malarial gametocytocidal agents.Malaria parasite clearance.New insight-guided approaches to detect, cure, prevent and eliminate malaria.Use of quantitative pharmacology tools to improve malaria treatments.Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.

P2860

Q27644391-AC4F80D7-C255-4C71-A180-0F273F0D13F7 Q28068072-130109E2-3E78-482D-B058-2BA3D828EEE9 Q28076750-FD4659FF-81EE-43B2-882C-6674894CC93F Q28468598-0C6615D6-C2A7-4100-B6E3-020C9BE97A9D Q28547546-8A33CCD0-BCE4-41EB-99A8-5D20E020E00A Q28554466-B0DDA8D6-80F6-4F46-A833-8FDB6C553D81 Q28649962-98748AF8-CC0F-41B2-A478-6314F020D36D Q30039505-76C8AD04-1BA1-49C9-94B3-5EA8542B51D6 Q30041353-092564FC-6C0F-483F-B317-92757727A082 Q30044020-AF2520FF-04C5-4943-9CFE-0E8C36F2EFBB Q33720859-39EF2996-1F6E-4551-A48C-AE6886BB52C3 Q33880789-5C87C8AF-3073-4EE6-8C93-F83D58917B38 Q34523425-86F48F4F-1FEE-4CA3-89E5-98EB423BDEA9 Q34597517-E1DD17A6-7747-477E-A913-DDEAC5076E81 Q34597823-720834D6-776C-4E52-B709-7DC25BADE0E6 Q34922792-EF062C9E-B7D8-41B6-8440-2A9328BFE379 Q34968407-EF905058-7C60-4858-873B-434655CA00D0 Q35076873-D9824EF7-F9DE-4325-ADB7-15DDC18427F6 Q35105899-D6DB57BF-B00B-475B-B25E-D9343E4C9BAA Q35563920-35B1B775-188C-4D4A-BA1B-985DBB79DB9B Q35584827-AEAF89E2-63FA-4CA8-A38C-411C3BC5EF59 Q35666885-1D815F63-3CA8-45CD-B8D7-82E03EA0FF9B Q35701564-8B8257E4-2D6F-43C3-A021-81F7BF44F01B Q35712615-ECA20114-5268-480D-BEBC-B4C1C8AB58DD Q35730764-92DD9F35-2C76-4F61-A3A1-B4ADD40B4DD4 Q35836828-A5F483AA-767A-4E8A-BC4F-A147ADA4B013 Q35860086-C13BF83D-AB19-4AD0-A65F-E2734518CBF4 Q35873837-A210780D-9E87-4A94-8959-F6CCAC6672A8 Q35898587-5B0DBEFA-54A4-4746-89E4-615861252559 Q35948587-CEA9541E-ACAF-4967-BB5E-BC2975D84AB6 Q36198846-52F24C81-BA03-4540-AB9D-26A677B094E2 Q36290632-CFC8863B-8B63-400F-AA8F-DBC0F74D82A4 Q36730061-CD38AA4D-C54A-4125-AC3E-E70BF676E5D1 Q36887899-85B696C3-AD31-45C5-B747-8106E26E640D Q37003081-EB7EBD4A-A33D-4561-8395-14F71D3DA813 Q37119522-4AB6283A-2468-4016-BA48-83E676ACEFBF Q37663369-3487BE07-5C29-42E3-A3FB-D5479EDD7DB4 Q38260909-C06A44BE-05E2-44E3-B403-0ECD2DE36935 Q38664529-502F59A2-6751-46D6-9745-DBF1BE24040C Q38911151-5A26CB1D-864A-4C30-BB9E-E8FDDE799852

P2860

Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs.

http://www.wikidata.org/entity/Q36969808

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Male and female Plasmodium fal ...... sponses to antimalarial drugs.

@en

type

label

Male and female Plasmodium fal ...... sponses to antimalarial drugs.

@en

prefLabel

Male and female Plasmodium fal ...... sponses to antimalarial drugs.

@en

P1433

Q36969808-7439D0DD-CAED-4AE1-8E96-59779FEDA610

P1476

Q36969808-82C002D1-F3BD-4F40-9BC7-EE0C97AF2A07

P2093

Q36969808-0012D7F6-0B68-40EA-B06B-40513E180F8A

Q36969808-813050FA-0353-428F-9840-BB44BE2E5F71

Q36969808-C0BC36AA-4F85-41F3-A894-DBEE710E1F8F

Q36969808-C4DB53DA-8D73-4A30-AE6E-DCB753E0E572

Q36969808-E090D062-5069-4993-AB0A-D98598392568

Q36969808-FF882419-2CBE-4955-8DE7-C706D26EFBEC

P2860

Q36969808-0228430E-0661-4652-898E-4E752D090F7D

Q36969808-0312C338-504F-46A7-9EFD-9F8217B5F147

Q36969808-03D2298B-9075-4FBE-AF64-1DDCEE4470A8

Q36969808-03E99383-F3CC-438D-A0E4-F28E103EFC42

Q36969808-13B22165-97D0-4641-9718-0067B1E01DC3

Q36969808-205F763A-E6A5-4248-8A54-EEF3A74DBBFB

Q36969808-2AFFCBD9-66A1-4C24-8671-12B36B8EFE3E

Q36969808-2D558826-126E-483D-9D87-870359B9918D

Q36969808-2F1C3955-BA1E-400D-A0FB-1509482EE884

Q36969808-33E369A6-EABD-40F0-806F-2B402DC8256A

P304

Q36969808-C4347795-86A7-4E8E-B860-69A2A4E7605F

P31

Q36969808-D7586F02-D8F9-4F9C-85B9-FB4DAD69CBD2

P356

Q36969808-9F7D1EDF-D3E0-44C8-A3A2-723D6CDDE8AB

P407

Q36969808-A1FA6230-0D98-4611-99EA-8E550122FEE1

P433

Q36969808-8137BBBC-D76A-4595-915C-DF3A022AB241

P478

Q36969808-882281DF-9D6B-4A6C-AB8C-B68FEC7C344C

P50

Q36969808-6D715C62-21F3-48F7-9116-57396D687BA0

Q36969808-BF7A8AC1-1B96-4E9A-AD7B-771537DBC867

P577

Q36969808-9A3DADC4-E030-4876-A114-7710E1EF0D40

P698

Q36969808-265AF72B-86E5-4164-B7B5-6A9741CB7703

P921

Q36969808-1C1A373C-BBD0-4600-9D25-F7EA9B9D32AD

Q36969808-534BC876-33A0-49A1-BAD1-F514754411A9

P932

Q36969808-7184B798-02F6-4FE1-8C33-C4F764007DE4

P356

P1433

Antimicrobial Agents and Chemotherapy

P1476

Male and female Plasmodium fal ...... sponses to antimalarial drugs.

@en

P2093

Esperanza Herreros

http://www.w3.org/2001/XMLSchema#string

Jöel Lelièvre

http://www.w3.org/2001/XMLSchema#string

María José López-Barragán

http://www.w3.org/2001/XMLSchema#string

Robert E Sinden

http://www.w3.org/2001/XMLSchema#string

Sara Marques

http://www.w3.org/2001/XMLSchema#string

Ursula Straschil

http://www.w3.org/2001/XMLSchema#string

P2860

Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: a randomised controlled trial

Interactions of methylene blue with human disulfide reductases and their orthologues from Plasmodium falciparum

Thiostrepton and derivatives exhibit antimalarial and gametocytocidal activity by dually targeting parasite proteasome and apicoplast

Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito

Promiscuous expression of α-tubulin II in maturing male and female Plasmodium falciparum gametocytes

The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites

Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence "transmission blocking" assay

Egress of Plasmodium berghei gametes from their host erythrocyte is mediated by the MDV-1/PEG3 protein

A central role for P48/45 in malaria parasite male gamete fertility

A research agenda to underpin malaria eradication.

P304

3268-3274

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/AAC.00325-13

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

57

http://www.w3.org/2001/XMLSchema#string

P50

P577

2013-04-29T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23629698

http://www.w3.org/2001/XMLSchema#string

P921

Plasmodium falciparum

P932

3697345

http://www.w3.org/2001/XMLSchema#string