The ATM substrate KAP1 controls DNA repair in heterochromatin: regulation by HP1 proteins and serine 473/824 phosphorylation - Wikidata - awgldk - TriplyDB

The ATM substrate KAP1 controls DNA repair in heterochromatin: regulation by HP1 proteins and serine 473/824 phosphorylation

The ATM substrate KAP1 controls DNA repair in heterochromatin: regulation by HP1 proteins and serine 473/824 phosphorylation

http://www.wikidata.org/entity/Q36972711

about

TRIM28 as a novel transcriptional elongation factor KAPtain in charge of multiple missions: Emerging roles of KAP1 Distinct phosphatases antagonize the p53 response in different phases of the cell cycle Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium HP1α mediates defective heterochromatin repair and accelerates senescence in Zmpste24-deficient cells.SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age.TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release.A KAP1 phosphorylation switch controls MyoD function during skeletal muscle differentiation.High levels of KAP1 expression are associated with aggressive clinical features in ovarian cancer Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase Chloroquine triggers Epstein-Barr virus replication through phosphorylation of KAP1/TRIM28 in Burkitt lymphoma cells Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model.Expression of KAP1 in epithelial ovarian cancer and its correlation with drug-resistance SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response.RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence.RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner Phosphorylation of KRAB-associated protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by nuclear tyrosine kinases inhibits the association of KAP1 and heterochromatin protein 1α (HP1α) with heterochromatin Interplay between Epigenetics and Genetics in Cancer.Activation of ATR-Chk1 pathway facilitates EBV-mediated transformation of primary tonsillar B-cells.The heterochromatic barrier to DNA double strand break repair: how to get the entry visa.The γH2AX DNA damage assay from a drop of blood.CCAR2/DBC1 is required for Chk2-dependent KAP1 phosphorylation and repair of DNA damage.Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway.The ATM inhibitor KU55933 sensitizes radioresistant bladder cancer cells with DAB2IP gene defect.mESC-based in vitro differentiation models to study vascular response and functionality following genotoxic insults.Function of heterochromatin protein 1 during DNA repair.Kruppel-associated Box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1β (HP1-β) mobilization and DNA repair in heterochromatin.Early age decline in DNA repair capacity in the liver: in depth profile of differential gene expression.Polyphenic trait promotes liver cancer in a model of epigenetic instability in mice.The complexity of TRIM28 contribution to cancer.And yet, it moves: nuclear and chromatin dynamics of a heterochromatic double-strand break.Potential Roles of Intrinsic Disorder in Maternal-Effect Proteins Involved in the Maintenance of DNA Methylation.Zbtb1 Safeguards Genome Integrity and Prevents p53-Mediated Apoptosis in Proliferating Lymphoid Progenitors Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivity A Novel HSP90 Inhibitor-Drug Conjugate to SN38 Is Highly Effective in Small Cell Lung Cancer.Preferential localization of γH2AX foci in euchromatin of retina rod cells after DNA damage induction.Heterochromatin and DNA damage repair: Use different histone variants and relax.KRAB-ZFP repressors enforce quiescence of oncogenic human herpesviruses.

P2860

Q26796250-6B3B22F6-0FB7-4041-8258-4A961E8EAC94 Q26822740-9370ED79-8E79-4F9A-BEEA-6AE65752B35C Q30578888-D3384C11-7A8C-408E-93D0-FADC37F7D502 Q30584877-E8C4A86B-1584-46D7-8A67-567EF60090F1 Q33728360-3F397D25-A3D9-4FC0-AA24-9611D9A4CA05 Q34289997-BD4606BD-B1BD-4816-866F-C33B6FB16E95 Q34307694-51DD360A-3624-497A-9B6C-B9984E81DB41 Q34465548-F31E91D5-F7B7-4A0B-868B-2DDE7B4BC73F Q35016445-9C7E8257-4C00-4DB0-879F-11E71733BDFA Q35260579-8BF11E7C-299D-46B8-B09F-5A984895B9B6 Q35532757-FC92D2FC-4622-490D-882F-961B780B4F02 Q36278928-EB2BFA38-ACB9-48B0-B959-DE66CFD0834E Q36294186-45DB0DE4-E0FE-49D1-AF11-B5730BEDF92B Q36358029-A57020D7-998B-4CE0-89FA-68C991D44D54 Q36411484-DEE4C8C5-6295-4701-9DA8-35CD7A5A1CF0 Q36478017-A8C8D507-77D3-4A69-A1B1-242AF1209AEB Q36798615-D9D2595F-F2E5-49FF-AF98-3D174A871654 Q36838400-8F83FB00-55CA-41F3-AB69-6E9C98F614C6 Q36929141-A41909EA-09EF-4E00-A6D0-90FD63633C98 Q37500876-CF3262E1-3221-4209-908E-13E1A8001717 Q37701620-488B1ABB-0C76-44B8-A562-99C07C2D15F8 Q38056496-899F8B7A-9C82-497F-A551-8E5B38C6B9DA Q38774044-E4366DA7-B799-494F-A38D-48C2C49F545A Q38855040-D8E0DD31-259A-495D-90F4-EFE47B600CE6 Q38869405-68FAF780-DDF3-4F59-B567-7C5DC1112278 Q38920371-222339B4-6787-4548-AFCC-5AD32AA9365E Q38927821-4923C79B-A73F-47D6-9793-DE6F467EDF60 Q39150008-AF287A70-2BA4-49D6-9CEF-921A9CA925F0 Q39328119-FC2DC166-B5B9-4E20-AF31-E7C289188B41 Q40027813-234E01EA-DAD9-49E2-AB94-4B1FCC88FCC5 Q40267153-9807B823-A677-49D0-912F-9A19B637E181 Q41542786-883F7876-B690-46AA-9A12-76A146471B33 Q41568442-250F7821-C59F-44C1-A03D-5DBC41342ADA Q41660989-D09C6339-0833-490B-8FC4-EE7F0DEA088B Q42147670-8045A46C-D85E-4126-BE12-6810C3BF4B14 Q42285151-4D95A375-4546-4CAB-897C-87D22CE717D3 Q42382771-E8751874-DF5A-484A-9014-BF1B5DA2EFFB Q45306835-F348DBCF-C322-4E97-A216-72702C4DA432 Q47595474-F3AFF839-223D-4957-A051-29C376EC8153 Q52563014-2FC67206-AA1B-4DA8-8F35-2D654C822F98

P2860

The ATM substrate KAP1 controls DNA repair in heterochromatin: regulation by HP1 proteins and serine 473/824 phosphorylation

http://www.wikidata.org/entity/Q36972711

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

The ATM substrate KAP1 control ...... serine 473/824 phosphorylation

@en

type

label

The ATM substrate KAP1 control ...... serine 473/824 phosphorylation

@en

prefLabel

The ATM substrate KAP1 control ...... serine 473/824 phosphorylation

@en

P1433

Q36972711-F36C9F80-CB7A-492C-949B-8958655B5336

P1476

Q36972711-321B9FE8-BC96-4189-B51C-D244FA885F83

P2093

Q36972711-02644C31-6032-4B79-AA41-522E7148C0DA

Q36972711-2AD69179-82CE-4B3C-906A-B95C2CDCB1A6

Q36972711-3F2682B5-0F2B-4664-B669-E0DD3738E43C

Q36972711-60499573-F6B8-43D3-9670-2B613AC9E389

Q36972711-7AFC41EE-A606-4752-BA4C-12E71E6117DB

Q36972711-892CEDA1-E61C-40C3-BB5B-0ADFCF13D486

Q36972711-DF8B075D-0BA2-49F6-8A75-51497D1071D3

Q36972711-E65CC96F-DE5E-4630-9579-7FF4595003C8

Q36972711-EC0EF204-D4BA-4E27-B20F-4DDAFAB8A551

P2860

Q36972711-038AD27A-02A9-4A68-8C3E-8FE97BC912E9

Q36972711-0A79C9E5-6825-4F9F-9BC9-0DBD756EED80

Q36972711-10694EBE-B2BB-4149-93CB-E41BE117A04A

Q36972711-1A22AE1A-B31E-4404-BC4A-B52EC35B5429

Q36972711-1E547421-7D5D-48E4-B3C8-F3F20EFF5099

Q36972711-1FCC622A-300F-428F-BB96-66E471D8E471

Q36972711-24493302-DE10-445B-B9BA-E5B06C6ACD99

Q36972711-295E9A63-3648-4C31-A5F6-C7F8DD5C20FF

Q36972711-2A18E7E9-6026-441F-9139-1EEF36DE102E

Q36972711-30CA80CC-7729-41C6-8DA1-265509F2FBAC

P304

Q36972711-F6A482D1-FBD8-48F7-B084-CF12F617160B

P31

Q36972711-5F5151A2-C99B-40AF-9282-A56D3063BCE5

P356

Q36972711-B17A3476-2414-4D27-A9B0-085D349DEAB5

P433

Q36972711-54EA0B2A-0B53-4D57-9F96-973353A64025

P478

Q36972711-E2C3A805-7CA2-488F-9F74-CE2EA775CEAD

P577

Q36972711-E93AFC25-32E0-481A-853E-701E571322BF

P698

Q36972711-33270BBB-CDDF-48E7-9FE2-B9430DF6969D

P921

Q36972711-2C15D62E-CEBE-4EBA-8524-B6083387924E

P932

Q36972711-24CCD3D8-1A81-4315-BE64-BC5612DB1676

P356

1541-7786.MCR-11-0134

P1433

Molecular Cancer Research

P1476

The ATM substrate KAP1 control ...... serine 473/824 phosphorylation

@en

P2093

Alexey V Ivanov

http://www.w3.org/2001/XMLSchema#string

Andrea Corsinotti

http://www.w3.org/2001/XMLSchema#string

David White

http://www.w3.org/2001/XMLSchema#string

Didier Trono

http://www.w3.org/2001/XMLSchema#string

Frank J Rauscher

http://www.w3.org/2001/XMLSchema#string

Hongzhuang Peng

http://www.w3.org/2001/XMLSchema#string

Ilona U Rafalska-Metcalf

http://www.w3.org/2001/XMLSchema#string

Sheng-Chung Lee

http://www.w3.org/2001/XMLSchema#string

Susan M Janicki

http://www.w3.org/2001/XMLSchema#string

P2860

KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing.

HP1gamma associates with euchromatin and heterochromatin in mammalian nuclei and chromosomes

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing

KAP-1, a novel corepressor for the highly conserved KRAB repression domain

KAP1, a novel substrate for PIKK family members, colocalizes with numerous damage response factors at DNA lesions

Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family

Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential

Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention

P304

401-414

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1158/1541-7786.MCR-11-0134

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

10

http://www.w3.org/2001/XMLSchema#string

P577

2011-12-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

22205726

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

4894472

http://www.w3.org/2001/XMLSchema#string