Elafin, an elastase-specific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosis
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Inhaled hypertonic saline for cystic fibrosis: Reviewing the potential evidence for modulation of neutrophil signalling and functionThe Role of Serine Proteases and Antiproteases in the Cystic Fibrosis LungNeutrophil plasticity enables the development of pathological microenvironments: implications for cystic fibrosis airway diseaseRaised trappin2/elafin protein in cervico-vaginal fluid is a potential predictor of cervical shortening and spontaneous preterm birth.Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production.Pulmonary proteases in the cystic fibrosis lung induce interleukin 8 expression from bronchial epithelial cells via a heme/meprin/epidermal growth factor receptor/Toll-like receptor pathway.Alpha-1 proteinase inhibitors for the treatment of alpha-1 antitrypsin deficiency: safety, tolerability, and patient outcomes.Potential of anti-inflammatory treatment for cystic fibrosis lung disease.A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.Protease inhibitor levels in periodontal health and disease.Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases.Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation.Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary diseaseDifferent responses to mechanical injury in neonatal and adult ovine articular cartilageProteases and antiproteases in chronic neutrophilic lung disease - relevance to drug discovery.Secretory leukocyte protease inhibitor and elafin/trappin-2: versatile mucosal antimicrobials and regulators of immunity.The cystic fibrosis neutrophil: a specialized yet potentially defective cell.The role of proteases, endoplasmic reticulum stress and SERPINA1 heterozygosity in lung disease and α-1 anti-trypsin deficiency.War and peace between WAP and HIV: role of SLPI, trappin-2, elafin and ps20 in susceptibility to HIV infection.SLPI and elafin: multifunctional antiproteases of the WFDC family.Proteases, cystic fibrosis and the epithelial sodium channel (ENaC).Alarm Anti-protease Trappin-2 Negatively Correlates With Proinflammatory Cytokines in Patients With Periodontitis.Antiproteases as therapeutics to target inflammation in cystic fibrosis.A secretory leukocyte protease inhibitor variant with improved activity against lung infection.Differential effects of periopathogens on host protease inhibitors SLPI, elafin, SCCA1, and SCCA2.Elafin expression in mucosa of fallopian tubes is altered by hydrosalpinx.Neutrophil elastase in bronchiectasis.α1-Antitrypsin deficiency.Airway Epithelium Dysfunction in Cystic Fibrosis and COPD.The impact of alpha-1 antitrypsin augmentation therapy on neutrophil-driven respiratory disease in deficient individuals.
P2860
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P2860
Elafin, an elastase-specific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosis
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Elafin, an elastase-specific i ...... dividuals with cystic fibrosis
@en
type
label
Elafin, an elastase-specific i ...... dividuals with cystic fibrosis
@en
prefLabel
Elafin, an elastase-specific i ...... dividuals with cystic fibrosis
@en
P2093
P2860
P50
P356
P1476
Elafin, an elastase-specific i ...... dividuals with cystic fibrosis
@en
P2093
Marcus W Butler
Nicolas Guyot
Noel G McElvaney
Rodney L Levine
Shane J O'Neill
P2860
P304
32377-32385
P356
10.1074/JBC.M803707200
P407
P577
2008-09-17T00:00:00Z