Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia - Wikidata - awgldk - TriplyDB

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

http://www.wikidata.org/entity/Q36980230

about

Peroxisome proliferator activated receptors at the crossroad of obesity, diabetes, and pancreatic cancer Notch Signaling in Pancreatic Development Developmental Pathways Direct Pancreatic Cancer Initiation from Its Cellular Origin Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract Mouse models of pancreatic cancer Molecular mechanism underlying lymphatic metastasis in pancreatic cancer Genetically engineered mouse models of pancreatic adenocarcinoma From fly wings to targeted cancer therapies: a centennial for notch signaling Pancreatic ductal cells in development, regeneration, and neoplasia Control of cell identity in pancreas development and regeneration Human correlates of provocative questions in pancreatic pathology Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineage Silencing Mist1 Gene Expression Is Essential for Recovery from Acute Pancreatitis Met receptor tyrosine kinase signaling induces secretion of the angiogenic chemokine interleukin-8/CXCL8 in pancreatic cancer A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas Utilizing past and present mouse systems to engineer more relevant pancreatic cancer models Regulation of Cellular Identity in Cancer Activated K-ras and INK4a/Arf deficiency cooperate during the development of pancreatic cancer by activation of Notch and NF-κB signaling pathways Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia Exocrine pancreatic carcinogenesis and autotaxin expression Leptin-Notch signaling axis is involved in pancreatic cancer progression Focused ultrasound-mediated drug delivery to pancreatic cancer in a mouse model.Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer.Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation.Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice.Loss of the acinar-restricted transcription factor Mist1 accelerates Kras-induced pancreatic intraepithelial neoplasia.Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity.Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model.The secret origins and surprising fates of pancreas tumors Basal but not luminal mammary epithelial cells require PI3K/mTOR signaling for Ras-driven overgrowth.KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.Identification of novel targets of CSL-dependent Notch signaling in hematopoiesis Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma.Adult cell plasticity in vivo: de-differentiation and transdifferentiation are back in style.Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras.PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia.PTEN loss accelerates KrasG12D-induced pancreatic cancer development Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models

P2860

Q26764921-0B11C43F-E80C-459D-B429-6069B29859F5 Q26771258-5E6BA36C-76BD-4504-8D82-9349BB3759CE Q26774942-85B5A975-F5D1-4C56-9608-0D908AF33B60 Q26801731-5D1B56AB-4F5A-4113-9636-C05FD543B709 Q26860574-B463E3BF-9024-4992-AC7A-AAF897F34DB2 Q26999345-0176D45B-0F70-4FE3-8574-EAB060E6CD91 Q27002973-A022617D-4B06-47DC-B8C9-E8C9C89E594C Q27004534-26655C56-0C15-43C0-88AD-3348B4447C69 Q27006729-F715B49D-BBC3-4443-B2BE-95D65C2CDCF4 Q27021239-406561DA-830D-41DD-9818-4D3DE1C9F1F8 Q27023576-38907B22-A0E6-4E04-941D-38DCD2B2B8E2 Q27312357-3AC42F85-6059-4A59-B0E1-6AF44705AD0A Q27334054-2C9D973A-4892-4409-B080-86008AC600F8 Q27334957-1A98CC96-CADB-4A1C-95FA-901BB19A3993 Q28082890-7837AA5E-0C26-4031-8C29-EE7553080405 Q28083091-2BDF0AF3-EC0F-4933-9C7A-B10BF4D210DC Q28086849-0009BB30-D41C-4FF4-A921-529BCB49A4BB Q28478427-A7FB284E-DEC5-45DB-AF0F-46154DFC7506 Q28480889-1D7BFD6E-6140-40FF-81FE-B05EF6E95136 Q28482954-0F04C0A6-6858-4F29-B332-AF414C3FA4F6 Q30396675-29DE7624-BD3D-4AE1-85D5-5BEF0D4EFDF0 Q30422901-0A4CA8A4-16B5-4166-949B-DF056D2358DD Q30581795-ED66B1F4-E379-4FE5-839D-B70F0F20F4C3 Q30620697-257152A7-FA80-4C50-B71A-B0EDB3870725 Q33486497-31451D7C-F070-4206-915F-7C02EA8260C1 Q33604913-6FC0DD3D-58E8-460B-A964-0DADC277E7D0 Q33754775-F3705558-2D2F-41DF-9B74-C18FA09D7FEF Q33767473-D98B1CFF-76B7-4424-A0E3-2380913C6320 Q33818230-7AB2C4B0-8C9E-49C4-B62B-4F35E3915D24 Q33827679-A8988B52-B53A-4C81-B0A7-5548A2298435 Q33832727-B90B978E-1C08-4FC0-B80F-D80004FBFA40 Q33858490-5B883EB1-C802-4347-BFB4-9258A7DFA234 Q33921337-F9497BBD-9A38-4B41-B307-B03CADD07BFD Q33976991-4B9981BF-6643-404A-BDCA-7142789A9B7F Q34046479-49D7947E-F539-45AE-9082-F9A800A2ACDB Q34068002-5A6DA88E-7DBA-4BA0-9721-B911E60AD30C Q34082522-DBCEF04F-7612-4F60-B0C6-DFDD78142152 Q34101017-F5FF89B5-3B2B-43A9-B1A6-649E0E35054D Q34134396-3E824EEA-8384-447F-AE84-D36B9DEA4C68 Q34201623-CC33E6D4-8474-407C-BFD3-9B0ADCE53B5C

P2860

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

http://www.wikidata.org/entity/Q36980230

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

@en

type

label

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

@en

prefLabel

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

@en

P1433

Q36980230-42071550-6EA0-4752-971E-E71508742376

P1476

Q36980230-24D7AF99-4332-4B87-98EC-CABAAB2429ED

P2093

Q36980230-0AA59FCA-46AE-424D-991A-CCEDF99B493A

Q36980230-3E2CFF4B-5EC6-4484-A5E9-DC9283A6AC56

Q36980230-5C399CB7-0E31-4E3D-A1B5-E09927D76C36

Q36980230-B1D2C543-B99B-4D1A-8A0B-D5D91A082FC7

Q36980230-EF77400F-4979-4C91-8138-6A2B025407E5

Q36980230-F599068A-F57F-44A5-B3DF-43DC1A287416

Q36980230-FD7104DF-68F4-4A9F-90B2-DAB6F7646209

P2860

Q36980230-08F11465-790F-4784-A693-5AFEA6BC7C1B

Q36980230-107CDAB6-3890-4418-A5B9-CF559245A164

Q36980230-14B121F7-4B84-441E-87EE-A382E3B558E7

Q36980230-1BAD5888-3E1F-4526-9599-B80E6EEDA00E

Q36980230-1CED8B95-F088-4908-B855-C47E2F2AFAFC

Q36980230-2D598004-6148-4770-9982-D2664395A388

Q36980230-3486D15F-7536-46A5-A62C-4B16D3FF1D0C

Q36980230-3BBF943C-80C7-43E9-9892-F9BAC82617BB

Q36980230-6227C46B-6A75-4F6B-920E-BA414B9A1B56

Q36980230-6B13F7AA-8448-4699-A4E9-D6ED69616D85

P304

Q36980230-35573E84-ADB3-4DE8-BE10-B261AFAFCFD2

P31

Q36980230-EA374182-5B3F-4A42-A5B3-5AF809D59229

P356

Q36980230-C04ED2E1-EA18-49B8-88FB-580F478E6FE3

P407

Q36980230-2196EA64-2F76-44C4-86DB-B63F2CA2EA53

P433

Q36980230-7ADF0204-50A1-4C6A-97E9-D5658F72A366

P478

Q36980230-F705EB19-B9DC-46C9-9EE0-C5B2E644E50D

P577

Q36980230-AC4D04F2-33C4-4EF6-914A-C4FD1979F417

P5875

Q36980230-306F71B9-A73D-4BB8-B710-C6A5D095426B

P698

Q36980230-1537FC03-23EC-4AA4-8747-197DD19D166D

P932

Q36980230-EA820044-2168-4CF6-897A-AC8E50FE06BC

P356

PNAS.0810111105

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

@en

P2093

Andrew B Curtis

http://www.w3.org/2001/XMLSchema#string

Benjamin E Illum

http://www.w3.org/2001/XMLSchema#string

Jean-Paul De La O

http://www.w3.org/2001/XMLSchema#string

Jessica L Goodman

http://www.w3.org/2001/XMLSchema#string

L Charles Murtaugh

http://www.w3.org/2001/XMLSchema#string

Lyska L Emerson

http://www.w3.org/2001/XMLSchema#string

Scott C Froebe

http://www.w3.org/2001/XMLSchema#string

P2860

Notch signaling controls multiple steps of pancreatic differentiation

Beta-catenin is essential for pancreatic acinar but not islet development

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

Pancreatic cancer.

A PCR primer bank for quantitative gene expression analysis.

Gene regulatory factors in pancreatic development.

Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.

The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia

Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia.

P304

18907-18912

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0810111105

http://www.w3.org/2001/XMLSchema#string

P407

P433

48

http://www.w3.org/2001/XMLSchema#string

P478

105

http://www.w3.org/2001/XMLSchema#string

P577

2008-11-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23492775

http://www.w3.org/2001/XMLSchema#string

P698

19028876

http://www.w3.org/2001/XMLSchema#string

P932

2585942

http://www.w3.org/2001/XMLSchema#string