Folding of conotoxins: formation of the native disulfide bridges during chemical synthesis and biosynthesis of Conus peptides.
about
Structure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activityThe NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathwaysDistinct Disulfide Isomers of μ-Conotoxins KIIIA and KIIIB Block Voltage-Gated Sodium ChannelsA synthetic combinatorial strategy for developing alpha-conotoxin analogs as potent alpha7 nicotinic acetylcholine receptor antagonists.Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins.Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels.A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domainA novel approach for in vivo screening of toxins using the Drosophila Giant Fiber circuit.Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.High yield production and refolding of the double-knot toxin, an activator of TRPV1 channels.Conantokin-P, an unusual conantokin with a long disulfide loopIdentification and Characterization of a Novel Family of Cysteine-Rich Peptides (MgCRP-I) from Mytilus galloprovincialis.Analgesic conotoxins: block and G protein-coupled receptor modulation of N-type (Ca(V) 2.2) calcium channels.Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides.NMR-based mapping of disulfide bridges in cysteine-rich peptides: application to the mu-conotoxin SxIIIAIntegrating the discovery pipeline for novel compounds targeting ion channels.Disulfide cross-linking influences symbiotic activities of nodule peptide NCR247.Optimal cleavage and oxidative folding of α-conotoxin TxIB as a therapeutic candidate peptideOn the importance of oxidative folding in the evolution of conotoxins: cysteine codon preservation through gene duplication and adaptation.Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds.Synthetic α-conotoxin mutants as probes for studying nicotinic acetylcholine receptors and in the development of novel drug leads.Glycosylation of conotoxins.Spider venomics: implications for drug discovery.Efficient oxidative folding and site-specific labeling of human hepcidin to study its interaction with receptor ferroportin.Site-specific effects of diselenide bridges on the oxidative folding of a cystine knot peptide, omega-selenoconotoxin GVIA.Integrated oxidative folding of cysteine/selenocysteine containing peptides: improving chemical synthesis of conotoxins.Oxidative Folding of Conopeptides Modified by Conus Protein Disulfide Isomerase.Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer.The Structure-Forming Juncture in Oxidative Protein Folding: What Happens in the ER?Chemistry and Enzymology of Disulfide Cross-Linking in Proteins.Stabilization of the cysteine-rich conotoxin MrIA by using a 1,2,3-triazole as a disulfide bond mimetic.Insights into the Folding of Disulfide-Rich μ-Conotoxins
P2860
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P2860
Folding of conotoxins: formation of the native disulfide bridges during chemical synthesis and biosynthesis of Conus peptides.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Folding of conotoxins: formati ...... iosynthesis of Conus peptides.
@en
type
label
Folding of conotoxins: formati ...... iosynthesis of Conus peptides.
@en
prefLabel
Folding of conotoxins: formati ...... iosynthesis of Conus peptides.
@en
P356
P1476
Folding of conotoxins: formati ...... iosynthesis of Conus peptides.
@en
P2093
Baldomero M Olivera
Grzegorz Bulaj
P304
P356
10.1089/ARS.2007.1856
P577
2008-01-01T00:00:00Z