Dual function of pancreatic endoplasmic reticulum kinase in tumor cell growth arrest and survival.
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Inhibition of eIF2alpha dephosphorylation inhibits ErbB2-induced deregulation of mammary acinar morphogenesisPERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy.PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damageInduction of apoptosis coupled to endoplasmic reticulum stress in human prostate cancer cells by n-butylidenephthalide.Diet-induced unresolved ER stress hinders KRAS-driven lung tumorigenesis.ERK1/2 and p38α/β signaling in tumor cell quiescence: opportunities to control dormant residual disease.Pancreatic endoplasmic reticulum kinase activation promotes medulloblastoma cell migration and invasion through induction of vascular endothelial growth factor AInduction of Apoptosis Coupled to Endoplasmic Reticulum Stress through Regulation of CHOP and JNK in Bone Marrow Mesenchymal Stem Cells from Patients with Systemic Lupus ErythematosusCell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapyOLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation.CD147 induces UPR to inhibit apoptosis and chemosensitivity by increasing the transcription of Bip in hepatocellular carcinoma.Microenvironments dictating tumor cell dormancyRegulation of autophagy during ECM detachment is linked to a selective inhibition of mTORC1 by PERKRegulation of tumor cell dormancy by tissue microenvironments and autophagy.Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis.Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer targetPERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Premalignant Granule Cell Precursor Apoptosis.The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapiesComputational identification of a p38SAPK-regulated transcription factor network required for tumor cell quiescenceInhibition of eIF2alpha dephosphorylation maximizes bortezomib efficiency and eliminates quiescent multiple myeloma cells surviving proteasome inhibitor therapyDual role of the integrated stress response in medulloblastoma tumorigenesis.Cellular and animal indispensable amino acid limitation responses and health promotion. Can the two be linked? A critical review.Molecular pathways: the PERKs and pitfalls of targeting the unfolded protein response in cancer.A stressful microenvironment: opposing effects of the endoplasmic reticulum stress response in the suppression and enhancement of adaptive tumor immunity.Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments.Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).Endoplasmic reticulum stress sensitizes cells to DNA damage-induced apoptosis through p53-dependent suppression of p21(CDKN1A).Development of transgenic mice expressing a conditionally active form of the eIF2α kinase PKR.Involvement of autophagy in the procedure of endoplasmic reticulum stress introduced apoptosis in bone marrow mesenchymal stem cells from nonobese diabetic mice.Tumor cell dormancy as an adaptive cell stress response mechanism.Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulum.Helicobacter pylori and Gastric Cancer: Adaptive Cellular Mechanisms Involved in Disease Progression.A deregulated integrated stress response promotes interferon-γ-induced medulloblastoma.NMT1 inhibition modulates breast cancer progression through stress-triggered JNK pathway
P2860
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P2860
Dual function of pancreatic endoplasmic reticulum kinase in tumor cell growth arrest and survival.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Dual function of pancreatic en ...... ll growth arrest and survival.
@en
type
label
Dual function of pancreatic en ...... ll growth arrest and survival.
@en
prefLabel
Dual function of pancreatic en ...... ll growth arrest and survival.
@en
P2860
P50
P1433
P1476
Dual function of pancreatic en ...... ell growth arrest and survival
@en
P2093
Aparna C Ranganathan
Shishir Ojha
P2860
P304
P356
10.1158/0008-5472.CAN-07-6215
P407
P577
2008-05-01T00:00:00Z