CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology. - Wikidata - awgldk - TriplyDB

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.

http://www.wikidata.org/entity/Q36990425

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Decreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretase Genes associated with Alzheimer's disease: an overview and current status Myeloid Dendritic Cells are Potential Players in Human Neurodegenerative Diseases Alzheimer's Disease: Mechanism and Approach to Cell Therapy Genetics ignite focus on microglial inflammation in Alzheimer's disease TREM2 in CNS homeostasis and neurodegenerative disease Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans Integration of multiscale dendritic spine structure and function data into systems biology models Mechanisms Underlying the Selection and Function of Macrophage-Specific Enhancers Late-Onset Alzheimer's Disease Genes and the Potentially Implicated Pathways Stem Cell Therapy: A Prospective Treatment for Alzheimer's Disease Microglia communication: Parallels between aging and Alzheimer's disease Alzheimer's disease: Unique markers for diagnosis & new treatment modalities APOE-modulated Aβ-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective Neuroinflammation in Alzheimer's disease Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data Mining Human-specific derived alleles of CD33 and other genes protect against postreproductive cognitive decline Regulation of microglial survival and proliferation in health and diseases.Microglia as a critical player in both developmental and late-life CNS pathologies.Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease.YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer's disease and other tauopathies.Ontogeny and functions of central nervous system macrophages.Siglec-mediated regulation of immune cell function in disease.SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration.Prostaglandin J2: a potential target for halting inflammation-induced neurodegeneration.Epigenomics of Alzheimer's disease.Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex The evolving biology of microglia in Alzheimer's disease.Association of Alzheimer's disease GWAS loci with MRI markers of brain aging Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease.APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages Effect of APOE and CD33 on Cognitive Decline.A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation.

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CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.

http://www.wikidata.org/entity/Q36990425

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2013 nî lūn-bûn

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2013年の論文

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2013年论文

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2013年论文

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2013年论文

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name

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.

@en

type

label

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.

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prefLabel

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.

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P1433

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Nature Neuroscience

P1476

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.

@en

P2093

Alina Von Korff

http://www.w3.org/2001/XMLSchema#string

Alzheimer Disease Neuroimaging Initiative

http://www.w3.org/2001/XMLSchema#string

Anna Tang

http://www.w3.org/2001/XMLSchema#string

Brendan T Keenan

http://www.w3.org/2001/XMLSchema#string

Denis A Evans

http://www.w3.org/2001/XMLSchema#string

Elizabeth M Bradshaw

http://www.w3.org/2001/XMLSchema#string

Julie A Schneider

http://www.w3.org/2001/XMLSchema#string

Keith Johnson

http://www.w3.org/2001/XMLSchema#string

Laura L Rosenkrantz

http://www.w3.org/2001/XMLSchema#string

Lori B Chibnik

http://www.w3.org/2001/XMLSchema#string

P2860

Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

“Mini-mental state”

Testing the right target and right drug at the right stage

Principal components analysis corrects for stratification in genome-wide association studies

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

GenePattern 2.0

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

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P304

848-850

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scholarly article

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10.1038/NN.3435

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P407

P433

7

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P478

16

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P50

David A Bennett

P577

2013-05-23T00:00:00Z

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262043301

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23708142

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P921

Alzheimer's disease

P932

3703870

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